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5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)- is a new pharmaceutical compound that has recently been introduced in the market for the treatment of various diseases.
The compound is a synthetic derivative of imidazo[2,1-d][1,4]benzoxazepine, which has been shown to have potent antiviral and antiparasitic activities in in vitro and in vivo studies.
The upstream products of 5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)- are the raw materials and intermediates that are required for the synthesis of the compound.
These raw materials and intermediates are typically sourced from chemical suppliers or synthesized in-house by pharmaceutical companies.
The downstream products of 5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)- are the finished dosage forms that are sold to patients and healthcare providers.
These finished dosage forms include tablets, capsules, suspensions, and solutions that contain the active ingredient and other excipients.
In the chemical industry, the upstream and downstream products of 5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)- can be synthesized using various chemical reactions and processes.
The specific methods used will depend on the availability and cost of the raw materials, as well as the desired yield and purity of the final product.
One way to synthesize the upstream products of 5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)- is to use a sequence of reactions such as Suzuki-Miyaura coupling, hydroboration-oxidation, and Pd/C-mediated
