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Imatinib (Piperidine)-N-oxide, also known as Gleevec, is a widely used cancer medication that was first approved by the U.
S.
Food and Drug Administration (FDA) in 2001.
The drug is primarily used to treat various types of leukemia and other cancers, and has become an essential part of cancer treatment for many patients.
In the chemical industry, Imatinib (Piperidine)-N-oxide is an important compound that is used as an intermediate in the production of other chemicals and pharmaceuticals.
Upstream Products
The production of Imatinib (Piperidine)-N-oxide begins with the synthesis of precursor compounds, which are then transformed into the active ingredient through a series of chemical reactions.
One of the key intermediate compounds used in the production of Imatinib (Piperidine)-N-oxide is 2-Hydroxy-4-(3-hydroxyphenyl)-6-oxo-piperidine-1,4-dione.
This compound is synthesized through a multi-step reaction process that involves the condensation of several precursor compounds.
The synthesis of 2-Hydroxy-4-(3-hydroxyphenyl)-6-oxo-piperidine-1,4-dione is a complex and challenging process that requires the use of specialized equipment and a high level of expertise.
Another intermediate compound used in the production of Imatinib (Piperidine)-N-oxide is N-Hydroxy-4-((2S)-2-(4-((2S)-2-(difluoromethyl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl)amino)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-8-yl)amino)-2-oxo-1,3-oxazolidin-3-ylpyridin-2-ylamide.
This compound is synthesized through a series of reactions that involve the condensation of several precursor compounds, as well as the use of specialized reagents and conditions.
Downstream Products
The production of Imatinib (Piperidine)-N-oxide is a critical step in the manufacture of several pharmaceutical products and chemicals.
Some of the most important downstream products include:
- Cenicriviroc: This is a pharmaceutical drug that is used to treat chronic hepatitis B infection.
Cenicriviroc is synthesized from Imatinib (Piperidine)-N-oxide through a series of chemical reactions that involve the introduction of specific functional groups. - Pegaspargase: This is a drug that is used to treat cancer.
Pegaspargase is synthesized from Imatinib (Piperidine)-N-oxide through a multi-step reaction process that involves the introduction of specific functional groups. - Copanlisib: This is a pharmaceutical drug that is used to treat several types of cancer.
Copanlisib is synthesized from Imatinib (Piperidine)-N-oxide through a series of chemical reactions that involve the addition of specific functional groups.
Conclusion
In conclusion, Imatinib (Piperidine)-N-oxide is a critical intermediate compound in the production of several pharmaceutical products and chemicals.
The production of Imatinib (Piperidine)-N-oxide involves several complex steps, including the synthesis of precursor compounds and the introduction of specific functional groups.
These downstream products are used to treat a variety of medical conditions and diseases, making Imatinib (Piperidine)-N-oxide an essential compound in the pharmaceutical and chemical industries.
As research continues to advance, it is likely that new and improved methods for the production of Imatinib (Piperidine)-N-oxide and its downstream products will be developed, leading to even more effective treatments for cancer and other diseases.
