The use of multiple antibiotics in patients with bacterial infections may promote the spread of drug resistance

The report, by researchers at the Hebrew University and Shaare Zedek Medical Center, suggests that the use of multiple antibiotics in patients with bacterial infections may promote the spread of drug resistanceresearchers looked at the treatment of a patient with Staphylococcus aureus in his bloodAt first, the doctor treated the patient with vancomycinWhen vancomycin does not relieve the condition, the doctor adds lifupine to the treatmentEight days later, doctors treated dattomycin instead of vancomycinin the process, the researchers took blood samples from patients to determine the effectiveness of the treatment, which allowed them to individually test the level stoais of microorganisms in the bloodIt was found that dattomycin killed bacteria more slowly after combining the drug, which meant that the bacteria were evolving resistance to dattomycinThe same was observed by the researchers while testing for other types of bacterial infectionsbased on this, the researchers believe that combining antibiotics with patients can make bacteria resistant to drugs that are still in effectAccording to a 2014 World Health Organization report, 10 million people worldwide will die each year from antibiotic-resistant infections each yearWhile researchers have been looking for ways to address bacterial resistance, it is important to take care not to overuse antibiotics to avoid more serious consequences:[1] Study suggests giving infected patients combinations of antibiotics may promote resistance[2] Effect of tolerance on the evolution of antibiotic resistance under drug combinations:? The consequences of overuse of antibiotics may be worse than you think