The world's first human challenge trial to infect healthy people with the new coronavirus has been approved

The trial is understood to recruit 90 adult volunteers between the ages of 18 and 30 who have no new coronary history or symptoms, no potential health conditions and known adverse risk factors for new coronavirus infections such as heart disease, diabetes or obesity.
These volunteers will be exposed to the new coronavirus in specialized isolation facilities, designed to help researchers understand how the body responds to the virus, how the virus is transmitted, the minimum number of viruses needed to cause infection, etc., thereby accelerating the understanding of the new corona vaccine, treatment methods, etc., the trial is expected to start within one month.
Also, before conducting the trial, volunteers must pass a health risk test and undergo a 17-day quarantine before they can participate in the challenge trial, during which they are closely monitored by experts and health care providers, and the volunteers undergo two new coronavirus tests after completing the trial, and only volunteers with negative results can leave the test site.
more than 12 months of follow-up after the trial ended, and the volunteers were not paid, but would be compensated about 4,500 pounds (about 40,000 yuan).
the trial, which was funded by the UK government for 33.6 million pounds ($300 million), was carried out by Imperial College London, the UK government's vaccine task force and clinical trial research firm hVIVO.
The Human Challenge Trials" help clinical researchers determine which vaccines are most likely to be successful, and allow scientists to compare the efficacy of candidate vaccines by testing them side by side to determine which is more effective, imperial college London said.
"Our top priority is to keep volunteers safe, and my team has been conducting more than 10 years of human challenge research using other respiratory viruses, none of which are completely risk-free, but human challenge partners work to ensure that risk is minimized."
," says Chris Chiu, professor of infectious diseases at Imperial College London. Peter Openshaw, co-researcher of the
Human Challenge Trials and director of the Human Challenge Alliance at Imperial College London, said: "Volunteers who deliberately infect healthy people with known human pathogens are by no means indispication, and such studies can undoubtedly go a long way in identifying the mechanisms of a disease, even those that have been studied so much.
" Although the study is to better understand the new crown, the study has caused great controversy, the Washington Post reported on the 17th, let healthy people infected with a potentially deadly virus, even in a controlled environment is really necessary? In response, the head of the UK's vaccine working group said: "The UK has some safe and effective vaccines, but it is vital that we continue to develop new vaccines and treatments for the new coronavirus.
"Considering that high doses of the virus can lead to serious consequences, the researchers said they would infect volunteers at the 20th possible dose, triggering virus replication with reduced symptoms."
To date, there have been nearly 110 million confirmed cases of new crown pneumonia and more than 2.43 million deaths worldwide, including more than 27 million confirmed cases in the United States and 490,540 deaths, according to real-time data on global outbreaks at Johns Hopkins University in the United States. India was followed by India with 10950201 confirmed cases and 156,014 deaths, followed by Brazil with 997,8747 confirmed cases, followed by the United Kingdom with 408,3092 confirmed cases and more than 110,000 deaths.