The world's top pharmaceutical companies "Innovation Lab Top 10" released: Bayer, Pfizer, Novartis...

From computer-aided drug design to gene editing technology is popular, emerging technologies are subverting the pharmaceutical industry
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With the development of the pharmaceutical industry, pharmaceutical companies and scientific research institutions are striving to find the strength to keep themselves leading the industry, and pharmaceutical innovation laboratories (accelerators) have emerged
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In this regard, the editor counted the top 10 list of innovation laboratories under top pharmaceutical companies around the world .

1.
AstraZeneca open innovation

The open innovation team hopes to speed up the exploration of new medical solutions and solve patient problems through cooperation
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To date, AstraZeneca has carried out 250 collaborations in the fields of new molecular profiles, compounds, and preclinical research
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Through the CoSolve quarterly plan under the open innovation framework, participants can submit proposals related to drug development challenges.
Its goal is to create "an open and cooperative scientific community
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"

• The AstraZeneca incubator established at the BioHub Research Center in Boston provides laboratories and guidance for selected biomedical research startups
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• At BioVentureHub in Gothenburg, biotech startups and academic groups can collaborate with AstraZeneca employees and use AstraZeneca’s laboratory equipment and materials
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       Well-known projects : The innovation team has established a partnership with the Cancer Institute UK (CRUK) to authorize CRUK personnel to access its clinical information and discovered molecular information.
As a result, the AstraZeneca team has been given priority for any possible drug development direction The right to negotiate
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       In addition, the team also cooperates with BicycleTherapeutics, TheCrick Institute and Merck to conduct early research and development of new drugs
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       2.
AbbVie Innovation Center

       Established in 2015, located in the research park of the University of Illinois
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       The center is mainly composed of R&D IT experts and university students.
It is committed to allowing students to gain industry experience while collecting new ideas.
The current focus area is digital health wearable devices
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       3.
Bayer Innovation Plan

       Bayer's innovation plan mainly focuses on four areas: R&D, employee innovation, social innovation and open innovation.
By developing corresponding solutions, it will respond to global challenges in the fields of health, agriculture and nutrition
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       Bayer has approximately 16,000 scientists in R&D centers around the world
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The LifeHubs collaborative work network, which operates in places such as Berlin and Singapore, provides a cooperation platform for entrepreneurs engaged in health and nutrition projects

       In addition, Bayer also owns 5 CoLaborator research spaces, providing incubators, laboratories, internal research permissions, and cooperation opportunities for early-stage startups in the life sciences field
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       Well-known project : The Bayer G4A Digital Medical Accelerator Project provides assistance to start-up companies developing innovative medical and health solutions in terms of workplace, technical guidance, financial support, and cooperation opportunities
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There are currently more than 150 startup companies participating in the program, including xbird and ModernFertility

       4.
GlaxoSmithKline Innovation Lab

       In addition to the global R&D center, the British pharmaceutical giant GlaxoSmithKline (GSK) also operates a number of innovation laboratories, including the Warren Innovation Laboratory and the Digital Laboratory
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       At the Warren Innovation Lab in New Jersey, GlaxoSmithKline can collect feedback from customers who have tried over-the-counter drugs in its Consumer Sensory Lab and Shopper Science Lab
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       In the digital laboratory, a team of data scientists and engineers is committed to accelerating the adoption of emerging pharmaceutical technologies
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       Through its "open innovation" strategy, GlaxoSmithKline aims to "encourage innovation for diseases in developing countries
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"

• The open laboratory in Tres Cantos, Spain brings together scientists, experts and scholars through its resources and platforms to jointly study malaria, tuberculosis and other global health issues;

• In the StevenageBioscienceCatalyst campus, provide support for biotech start-up companies and help them realize the commercialization of technology through cooperation;

• The research and development of the open laboratory is to better study the variation of non-communicable diseases, including cancer and diabetes in Africa
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       Well-known project : The research team of the Warren Innovation Lab has developed an SSL e-commerce evaluation tool.
By embedding new images on the retailer's operating website, GlaxoSmithKline can monitor the shopping experience of shoppers on different versions of the website in real time
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       5.
Johnson & Johnson Innovation

       Since 1979, Johnson & Johnson’s mission of innovation has been to improve human health through innovation
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       Its four teams complement each other and work together to build a global network that aims to provide innovative and transformed medical and health solutions
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• The global innovation centers located in Boston, London, South San Francisco and Shanghai serve as regional centers to connect local entrepreneurs, scientists and new technologies;

• Provide an incubator for entrepreneurs in the medical and health field through JLABS;

• JJDC, its venture capital arm, has invested in multiple stages in the medical and health field;

• The subordinate Janssen Business Development Department is committed to cooperating with other entities or completing mergers and acquisitions
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       Well-known project : With the help of the JLABS incubator, Arcturus Therapeutics found a way to deliver RNA drugs to cells infected with hepatitis B virus
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       Since then, Arcturus has established a partnership with Johnson & Johnson's Janssen Business Development Department and signed a global license worth US$2 billion
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       JLABS recently launched the "Blue Knight" program in cooperation with the U.
S.
Biomedical Advanced Research and Development Administration (BARDA) to provide funding and guidance to target startups to help them develop solutions to the COVID-19 pandemic
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       6.
Medtronic Innovation Lab

       The Innovation Lab was established in 2015 and represents Medtronic's transformation towards the future
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In addition to developing medical equipment, the company also focuses on the development of digital solutions for chronic diseases

       As part of the "people-oriented" design concept, the core components of the laboratory are equipped with a 360-degree video projection screen to provide the team with an immersive experience and understand the needs of medical experts
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The laboratory equipment can also track the patient's experience, highlighting the challenges that patients need to face in their daily lives

       Well-known project : The laboratory cooperated with the humanitarian organization Alight, adhering to the "people-oriented" concept to formulate the Amandi Care Plan to provide assistance for better humanitarian relief work in Rwanda
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       7.
Merck Observation Data and Real World Evidence Center

       Large pharmaceutical companies often need to provide the true results and accurate data of their treatments.
For this reason, Merck created the Center for Observational Data and Real World Evidence (CORE) in 2014
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       The center unites Merck’s internal research groups, and cooperates with insurance companies and other external groups to collect the necessary data to track the efficacy and value of drugs
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These real-world evidence can be used to supplement trial data to show the results of treatment more comprehensively

       Well-known projects : In 2019, the Real World Data Exchange (RWDEx) cloud analysis platform was launched to promote the storage, management and sharing of real world data evidence within the company
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       8.
Novartis Microsoft AI Innovation Lab

       In 2019, Novartis cooperated with Microsoft to establish an AI Innovation Lab, integrating Novartis' database and research capabilities with Microsoft's AI solutions and data management expertise
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       The plan aims to:

• Use the Microsoft AI model to help the Novartis team gain more discoveries in the medical field from the data set;

• Use the power of AI to accelerate the exploration of "some of the most difficult computational problems in the field of life sciences"
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       In addition to the cooperation with Microsoft, Novartis has also launched NovartisBiome, a digital medical innovation accelerator worldwide, to jointly develop digital medical solutions with external partners, relying on Novartis' resources and clinical trial data
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       Known projects : the use of machine learning model is age-related macular degeneration (AMD) patients to develop individualized treatment programs; better administered to a patient using the guidance of the frequency data such as retinal scans of patients with AI model helps clinicians
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       9.
Pfizer Innovation Center for Treatment Field

       The therapeutic innovation center established by the pharmaceutical giant Pfizer in 2010 aims to promote drug development through cooperation with external researchers
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The innovation center’s laboratories are located in four cities in the United States, and through cooperation with external parties, “accelerate the transformation of concepts into feasible therapies”
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       10.
Roche pRED Innovation Center

       The pharmaceutical giant Roche has gathered 2,200 scientists and experts in 7 PRED innovation centers in cities such as Basel, Copenhagen and New York to achieve the ultimate innovation through cooperation and information sharing
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       In addition, Roche has an InnoLAB innovation laboratory that focuses on digital innovation
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       Well-known project : In January 2021, Roche cooperated with biotechnology company Ribometrix to develop small molecule drugs targeting RNA
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       According to the terms of the agreement, Roche will provide Ribometrix with US$25 million as start-up capital, and will pay more if certain milestones are achieved
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Prior to this, in April 2020, Roche had invested US$190 million in ArrakisTherapeutics and carried out similar cooperation
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       Editor in charge: Octagon

       Disclaimer: The opinions of this article only represent the author, not the position of Yaozhi.
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