Theory-Mechanism-Clinical, multi-target intervention of Jinlida granule has significant effect on diabetes

Epidemiological data shows that there are currently more than 100 million diabetic patients in my country, which is the first in the world.

Aiming at the prevention and treatment of diabetes and its complications, the collateral disease theory constructed by Academician Wu Yiling puts forward the viewpoint of treating diabetes from the "spleen" and developed the patented Chinese medicine Jinlida Granules, which adds safe and effective treatment options to the clinic.

Theoretical advantages, "Tongs the spleen and collaterals, moves the spleen and fluids" is the treatment principle throughout the management of type 2 diabetes

Traditional Chinese medicine has a long history of preventing and treating type 2 diabetes.

As an innovative Chinese medicine developed under the guidance of the theory of collateral disease, Jinlida Granules perfectly fits the theory of treating diabetes from the "spleen".

On the basis of Jinlida granule "Yunpijin" combined with Tongxinluo capsule "Tongpiluo" treatment, it can further improve the islet microcirculation and reduce systemic vascular complications.

Professor Chen emphasized that Chinese medicine treatment of diabetes can make up for the insufficiency of western medicine in the prevention and treatment of diabetes-related symptoms and microvascular complications.

Combining western medicines such as metformin with Jinlida granules can benefit more diabetic patients

In the current treatment of type 2 diabetes, metformin is the first choice for drug treatment.

The combined treatment program can lower blood sugar from different aspects, and has a better effect than metformin alone.

In 2015, an evidence-based study led by academician Tong Xiaolin of the Chinese Academy of Sciences included 192 patients with type 2 diabetes who were treated with metformin for 3 months with poor blood sugar control.

From "regulation" to "ping", Jinlida granules play a multi-pronged role in lowering blood sugar

On the basis of the first two speakers, Professor Ren Wei combined with the pathogenesis of type 2 diabetes to further analyze the mechanism of Jinlida granule in reducing blood sugar.

Professor Ren Wei introduced that the occurrence and development of type 2 diabetes involves many factors, and Jinlida granules mainly improve insulin sensitivity and pancreatic β-cell secretion, while regulating blood sugar hormones to achieve blood sugar regulation.

A series of basic studies have shown that in improving insulin resistance, Jinlida granules can: ①Relieve glycotoxicity and improve insulin resistance; ②Reduce triglyceride levels, reduce the secretion of inflammatory factors in adipocytes, and promote the secretion of adiponectin to improve insulin resistance; ③Improve liver function, reduce liver fat accumulation, and slow down the occurrence and development of non-alcoholic fatty liver.

In addition to the above effects, Jinlida Granules can also regulate the level of somatostatin, adrenaline and corticosterone and other blood glucose-increasing hormones to achieve a balance between it and insulin, and exert a systemic effect from "regulation" to "ping", which is effective Lower blood sugar.

Focusing on the elderly, Jinlida particles help individualized management of elderly diabetic patients

With the aging of our country's population, the management of elderly diabetic patients is a key topic of clinical concern.

Professor Zhu pointed out that elderly diabetic patients have the clinical characteristics of large blood glucose fluctuations, high risk of hypoglycemia, many complications, multi-drug combination, and type 2 diabetes as the main morbid population.

The above-mentioned RCT stratification analysis led by Academician Tong Xiaolin showed that Jinlida Granules has a better anti-diabetic effect on elderly diabetic patients, at the same time it can also reduce the TCM syndrome score, and significantly improve the symptoms of dry mouth and thirst.

Another study showed that combined use of Jinlida granules on the basis of insulin aspart 30 injection and metformin can improve blood sugar fluctuations, make blood sugar more stable, and do not increase the occurrence of hypoglycemia events.
For patients with prediabetes, a study evaluating the effect of Jinlida granules on the prognosis of elderly patients with coronary heart disease and impaired glucose tolerance showed that Jinlida granules can effectively reduce the incidence of cardiovascular events in patients.

In conclusion, Professor Zhu Danping pointed out that for the special group of elderly type 2 diabetes patients, individualized blood glucose management is very important, including setting individualized blood glucose control goals and individualized drug treatments.
The addition of traditional Chinese medicine is beneficial Better patient management.

Conclusion

With the continuous development of research and the deepening of understanding, the treatment of diabetes with Chinese medicine has been recognized more and more.
With the treatment of diabetes with Chinese medicine written into my country's guidelines, integrated traditional Chinese and Western medicine has become the mainstream strategy for diabetes prevention and treatment.
Based on sufficient evidence-based medical evidence, Jinlida Granules guided by collateral disease theory, as a Chinese patent medicine for diabetes treatment recommended by my country's Type 2 Diabetes Prevention and Control Guidelines, can exert systemic effects on multiple targets and bring multiple benefits to patients.
It is undoubtedly clinical A good weapon for diabetes management.
(Source: China Medical Tribune)

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