There is new evidence that the new coronavirus originated in nature

the outbreak of neo-crown pneumonia, researchers around the world have raced to investigate and analyze and scientific research. In addition to studying how to prevent and treat patients with neo-coronary pneumonia, a large part of the research focuses on how the new coronavirus is produced, when and where it first appears, when it begins to spread from person to person, whether the virus comes from bats, whether there is an intermediate host before it is transmitted to humans, and why the new coronavirus can spread so quickly from person to person. More than half a year has passed since then, and there is no consensus among the scientific community on these issues. Recently, Russian scientists may be interested in studying some of these issues.
Panchin
a biologist at russia's Institute for the Transfer of Information, after analyzing a large number of mutations in the genome of the new coronavirus, came to the important conclusion that the new coronavirus originated in nature.
Panchin, a professor of research, published his findings in the American Journal of Peer Review Science. Russia's Tass news agency (hereinafter referred to as Russia's Tass news agency) and the News Agency and other media also reported on this.
Panchin compared the accumulation of mutations in the genomes of new coronavirus, SARS virus and common cold viruses to study the probability of relative mutations in genes after these viruses infect humans, OTS reported. After comparing the genomes of more than 1,000 new coronavirus, more than 200 SARS viruses and more than 40 common cold viruses, as well as genes of similar animal coronavirus, the researchers found that 1,000 to 2,000 genetic mutations exist in the genomes of all human infections, meaning that genetic mutations occur largely after a person has been infected with the virus.
researchers have further found that the new coronavirus has a very significant characteristic, which does not exist in other coronavirus. There are many abnormal mutations in the genome of the new coronavirus, which cause the genetic ostrich (G) molecule to be replaced by uracil (U), one of the four "letters" that make up the RNA and DNA strands. The proportion of mutations in the genome of the new coronavirus is close to 15%, which is almost 10 times the genetic mutation of the new coronavirus before it infects people.Alexander Panchin,
Reconsumed, said: "We found that the proportion of ostrich mutations into uracils in the new coronavirus genome increased almost tenfold after the virus spread to humans, a feature that is barely visible in the genomes of SARS virus pathogens and does not have such characteristics in the cold virus genome." The
also found that the number of ostriches replaced by uracils before and after other coronavirus infections in humans was largely the same, said Alexander Panchin, a professor at the University of The United States. This unique feature of the new coronavirus also exists in virus genes in the United States, China and other countries, he said.
Based on this characteristic of the new coronavirus, Alexander Panchin suggests that long ago, the new coronavirus infected bats, but the cells of bats protected themselves well, and that the virus mutated less in bats, and bat cells and new coronavirus symbated; After the coronavirus infects people, the human tissue does not have the protective characteristics to deal with the virus, the human body may have a high level of oxidative stress response, resulting in the destruction of many of the genes of ostrich, the mutation of the gene began to accumulate, accumulated to a certain extent the nature of the change, the virus became aggressive.
Panchin, a professor at the University of New China, said the findings showed that the new coronavirus originated in nature.
, according to the World Health Organization statistics, the cumulative number of confirmed cases of new crown pneumonia has exceeded 19 million, the cumulative number of deaths more than 700,000, the epidemic is still spreading rapidly around the world. It is urgent for countries around the world to improve their ability to prevent and treat new coronavirus, and scientists around the world still have a long way to go in the face of the traceability of new coronavirus.
(Science and Technology Daily Moscow, August 10th)