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The new coronavirus infection rate is high and continues to wreak havoc around the worldIn addition to not grouping, wearing masks and other protective means, the world is concerned about the development of vaccinesWhen will it be available? At what stage? Recently, the American Thoracic Association director of international affairs, the University of Southern California respiratory and critical care medicine Professor Joe Li online interview with the U.SEast-West Coast program "Rush Hour" to discuss the above issues, Joe said the vaccine is the equivalent of the most effective preventive drugsThe world is particularly concerned about vaccine development, especially in the United States and China, creating a competitive trendNo fewer than 50 pharmaceutical companies, large and small, are involved in vaccine developmentThere are three ideas for the development ofvaccine research:1.
2.
3, like drug research and development, vaccines to enter clinical use need to go through three phases of clinical trialsThe first phase is proven to be effective in the case of cell culture or animal testing, and the second phase is to be used in small-scale human sand to prove its safetyThe first two steps were achieved in order to enter the third phase of large-scale human trialsA vaccine is already under way in Phase III clinical trials in China and the United States, however, Joe pointed out that the uncertainty of the third phase of the trial is so great that it often takes 10 years for a drug to develop into a clinically used drug For example, the only drug currently considered (reluctantly) effective against the new coronavirus, Redsiwe, has failed two phase 3 trials in the Ebola and Moss virus pandemics Under the strict conditions of reality, whether the effect achieved in the laboratory can be seen in human use is not obvious Moreover, in large-scale applications in the human body, it may also produce unexpected side effects has strict standards for new crown vaccines, from development to clinical trials "The FDA requires that specific antibodies are produced after vaccination scored more than 50 percent of the time they are not vaccinated So there is still a long way to go before we can develop a vaccine that meets this target without serious side effects "
currently has more than 3 million confirmed cases of new coronavirus in the United States, making it the largest in the world On the question of how to avoid infection, Professor Qiao cited Chinese experience In the early days of the outbreak, nearly 3,000 health care workers in Wuhan were infected, paralysing the local medical system Subsequently, the national mobilization of support, more than 40,000 medical personnel retrograde Wuhan support, and ultimately medical staff were rarely infected How did you do that? is strict protection, including strict isolation of the disease area and personal protective equipment The basic mechanisms of isolation and personal protection rely on only physical barriers that prevent virus particles from reaching the skin and entering the respiratory tract The mechanism is simple, but it is very effective if strictly enforced ", for the common people, protection is to go out as little as possible, go out must wear a mask, go home after all the clothes on the street, take a bath, and then contact with family Joe said (
) the original title: Dr Xiao Wei in the United States, to develop a qualified and side-effect-free vaccine, there is still a long way to go.