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Background: Patients with Graves disease are usually treated with radioactive iodine
.
There are still controversies as to whether the purpose of treatment should be normal thyroid function or hypothyroidism, and whether the treatment should be treated with standard levels of radioactivity or personalized treatment based on the absorbed radiation dose provided to the thyroid
Patients with Graves disease are usually treated with radioactive iodine
Results: A total of 1122 studies were included, 15 of which, including 2303 patients with Graves disease, were eligible for the meta-analysis
.
The radiation absorbed dose is closely related to the prognosis of non-hyperthyroidism and hypothyroidism (OR=1.
Table 150, 200, and 300 Gy irradiation for normal thyroid function, hypothyroidism and non-hyperthyroidism
.
.
Figure The proportion of people with non-hyperthyroidism, hypothyroidism, and normal thyroid function in patients with Graves disease during a median follow-up period of 12 months as a function of the absorbed radiation dose
.
The top number represents a total of 2303 patients, while the bottom two numbers represent a total of 1172 patients
Figure The proportion of people with non-hyperthyroidism, hypothyroidism, and normal thyroid function in patients with Graves disease during a median follow-up period of 12 months as a function of the absorbed radiation dose
The given radiation absorbed dose-response relationship can facilitate the individualized treatment plan for patients with Graves' disease treated with radioactive iodine
Taprogge J, Gape PM, Carnegie-Peake L,et al.
A systematic review and meta-analysis of the relationship between the radiation absorbed dose to the thyroid and response in patients treated with radioiodine for Graves' disease.
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