Thyroid: The efficacy of radioactive iodine in patients with hyperthyroidism in elderly subclinical hyperthyroidism 巯 long-term use of methamphetone.

Recently, a study published in Thyroid, a authoritative journal in the field of thyroid disease, compared the effectiveness and safety of radioiodine (RAI) and long-term methyl methyl (MMI) in the treatment of subclinical hyperthyroidism in the elderly.
the researchers selected 83 patients with hyperthyroidism aged 65 from 306 subclinical hyperthyroidism patients.
, 41 and 42 patients were randomly treated with RAI or long-term MMI in this randomized parallel trial.
in the RAI and MMI groups, 3 and 4 patients were excluded due to side effects, other treatment options and no follow-up, and 35 and 36 patients in the two groups completed 60 months of follow-up, respectively.
after 60 months of treatment with a fixed dose of 15 mCi RAI, 23 (66%) patients became hypothyroid patients and 12 (34%) patients had normal thyroid function.
in the MMI group, the starting dose was 10 mg per day, which was reduced to 4.9?1.0, 4.3?1.0, 4.4?1.4, 4.3?1.8 and 3.7?1.3 mg after 1, 2, 3 years of continuous MMI treatment, respectively.
the end of the study, 34 (94%) patients had normal thyroid function and 2 patients with dispersive goiter developed spontaneous hypothyroidism.
the first four months of treatment, both groups experienced minor adverse events.
no deaths or serious side effects were observed during the 60 months of follow-up.
, RAI and long-term low-dose MMI therapy are effective and safe for elderly patients with subclinical hyperthyroidism.
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