-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
University of Birmingham has found a new way to effectively kill cancer cells by destroying the "protective wall" around cancer cells.
The team led by the university's academics took samples of myelin-based inhibitory cells (MDSCs) from 200 newly diagnosed cancer patients, which emit a large number of chemical signals to shield tumor cells, prevent the immune system and immunotherapy from functioning, and prevent T-cells that kill tumor cells from being activated.
According to the report, published in E Biomedical, the team found that in many types of cancer, a protein called CD33 is present on the surface of MDSCs, and an antibody drug that has been used to treat acute myeloid leukemia can target CD33, eventually killing MDSCs and restoring T-cells' ability to attack tumor cells. Dr Francis Musai, of the University of Birmingham, one of the report's authors, said existing immunotherapy often failed to kill cancer cells effectively because the immune system often failed to reach them. Next, the team plans to test the effectiveness and safety of this approach through clinical trials. (Beijing Daily)