Top 10 Medical Innovations of 2021. What medical innovations will affect the world.

Cleveland Clinic recently announced its top 10 medical innovations for 2021, completing its 2020 Medical Innovation Summit.
fact, every year, near the end of the Health Innovation Summit, the Cleveland Clinic announces a list of medical innovations that could affect the world next year, a tradition that has been going on for 18 years.
this year, 10 medical innovations, including emerging gene therapy for blood diseases, new drugs for cystic fibrosis, and booming telemedicine, were on the list.
The following is the top 10 medical innovations of 2021, as expected: 1. Hemoglobin disease gene therapy hemoglobin disease is a genetic disease that affects the structure or production of hemoglobin molecules, which play an important role in transporting oxygen in the blood.
most common hemoglobin diseases include sickle cell disease and thalassemia, affecting 330,000 children and more than 100,000 sickle cell disease patients worldwide each year.
new study has led to an experimental gene therapy that gives people with the disease the potential to make functional hemoglobin molecules and prevent complications.
2. The new drug multiple sclerosis (MS), a new drug for primary multiple sclerosis, is one of the most common central neurodemic diseases.
immune system attacks fat-protected myelin, which covers nerve fibers, causing communication problems between the brain and other parts of the body, leading to autoimmune diseases of its demyelination.
about 15% of these MS patients have primary ongoing disease.
-based Roche Pharmaceuticals' Ocrelizumab is a new FDA-approved therapeutic monoclonal antibody with a new target and the first and only treatment for patients with primary progressive MS.
pacemaker devices connected to smartphones have traditionally been remotely monitored by pacemakers and defibrillators via bedside consoles and transmitted to doctors.
because many people lack understanding of this device and its functions, remote monitoring compliance is poor.
pacemaker devices connected to smartphones and tablets allow seamless access to patient life and secure and direct communication, enabling doctors to better track patients.
Cystic Fibrosis (CF), a new drug for cystic fibrosis, is an inherited endocrine gland disease that mainly affects the gastrointestinal tract and respiratory system.
the disease is caused by the defective cystic fibrosis transfilm conductivity regulator (CFTR) protein, a class of drugs called CFTR regulators that correct the protein's effects, but previously developed drugs are only effective for some people.
October 2019, the FDA approved Trikafta, a combination therapy for Vertex Pharmaceuticals, a fixed-dose combination of CFTR regulators and chlorine channel open agents that relieve patients with the most common CF gene mutation (F508 del), which is expected to account for 90 percent of the total patient population.
. Universal hepatitis C treatment was classified as a "silent epidemic" by the U.S. Centers for Disease Control and Prevention (CDC), and three scientists who discovered the disease recently won the Nobel Prize in Physiology or Medicine.
hepatitis C virus can lead to serious health problems such as liver failure, cirrhosis and liver cancer.
because there is no vaccine against the virus, patients can only use medication, the problem is that many drugs either have obvious side effects or are only effective for some patients.
2016, the first hepatitis C drug, Epclusa, was approved for sale, significantly improving the treatment of hepatitis C.
the drug effectively inhibits proteins that play a key role in HCV RNA replication, covering six genotypes of hepatitis C with an efficiency of more than 90%.
6. Bubble CPAP improves lung function in premature children, which usually requires special care.
For infants with infant respiratory distress syndrome (IRDS), doctors usually give them surfactants during mechanical ventilation, but this can cause long-term lung damage in premature babies and lead to the development of chronic lung disease.
The Baby Positive Pressure Respiratory Therapy System (b-CPAP) is a non-invasive breathing strategy that provides the newborn with continuous positive pressure in the air, helping them maintain lung volume during exhalation, minimizing physical trauma in premature babies and stimulating lung growth over long periods of use.
. Innovative practices and new policies have increased the use of telemedic services during the new crown pneumonia pandemic.
thanks to innovative practices and policy changes, more and more virtual care models and telemedicme are being implemented, medical services are accelerating, and the safety of health workers and community workers is guaranteed.
these changes open the floodgates for telemedicme and push for further widening of its path.
8. Vacuum-induced uterine fillers used for postpartum haemorrhage and post-natal bleeding are terrible complications after childbirth, and patients may need to take medications with dangerous side effects, undergo surgery for long-term discomfort, or even have their uterus removed and infertile in an emergency.
about 1 to 5 percent of pregnant women who give birth may face postpartum bleeding.
Previously, the use of airbag equipment to compress bleeding sites was a common non-surgical intervention, but the latest vacuum-induced uterine pressure plugters used negative pressure generated in the uterus to cause the bleeding chamber to collapse, more physiological than balloon compression, providing another minimally invasive way to deal with postpartum complications that could benefit more patients.
, the PARP inhibitor of prostate cancer, is a common male cancer, and about one in nine people will be diagnosed with prostate cancer in their lifetime.
, a pharmacological inhibitor used in cancer treatment, prevents tumor cells from repairing damaged DNA, thereby increasing tumor cell death, especially those with repair mechanism defects.
two PARP inhibitors, Rucaparib and Olaparib, have been shown to delay the progression of prostate cancer in men and were approved for use in May this year.
10. Migraine, an immunological migraine prevention drug, is the most common type of primary headache in clinical practice.
There has been a long history of using multi-purpose drugs such as blood pressure drugs, antidepressants, anti-epileptics and botulinum toxin injections to prevent migraines, but these are ineffective because they are not specifically targeted at migraines.
2018, a new drug to prevent migraines was introduced that works by blocking the activity of the calcitonin gene-associated peptide (CGRP) molecule, which surges during migraines.
February 2020, the FDA approved the first intravenous drug to prevent migraine, eptinezumab-jjmr, for preventive treatment of migraines in adults.
these new drugs are helping countless patients get back to normal life and work.
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