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Among the transition elements, vanadium , chromium , manganese , iron , cobalt , nickel , copper , zinc , and molybdenum are trace elements necessary for life, and most of them are the fourth period elements (Table 16-2)
.
Table 16-2 The content of essential transition elements in human body
Iron is the transition element with the highest content in the human body.
The content in the human body is 4.
2~6.
Zinc is the active center of many enzymes and participates in various metabolic processes
.
For example, the synthesis and degradation of carbohydrates, lipids, proteins and nucleic acids; zinc is related to bone and intellectual development, and zinc deficiency may cause dwarfism; zinc coordination compounds play a buffering role in the pH control mechanism in the body; carbonic anhydride Enzymes can catalyze the reaction of CO 2 and H 2 O, so that CO 2 in the body can be discharged from the body in time
.
The content of cobalt in the human body is only 1 to 2 mg, concentrated in the liver, mainly in the form of vitamin B 12 and its derivatives, and has the function of treating anemia
.
Cobalt plays a role in organisms in coenzymes, promotes the maturation of red blood cells, participates in protein synthesis, hydrogen and methyl transfer, and participates in redox reactions
.
Copper contains 100-150mg in the human body, and more than a dozen enzymes have been found to contain copper
.
Iron absorption and utilization process requires plasma ceruloplasmin involved
.
Molybdenum participates in metabolism, can prevent the synthesis of nitrous acid and has anti-cancer effects
.
The active center of nitrogenase is Mo-Fe protein or Mo-Fe-S protein, which plays an extremely important role in the process of biological nitrogen fixation
.
Manganese is an activator of certain enzymes and a cofactor for respiratory enzymes in mitochondria
.
Nickel exists in the serum of humans and mammals
.
Studies on animals have shown that a lack of nickel will affect the absorption of iron and reduce the amount of hemoglobin and the number of red blood cells
.
Chromium is a cofactor of insulin, and insulin has the function of promoting sugar metabolism
.
Chromium inhibits the synthesis of cholesterol and fatty acids, affects the utilization of amino acids, and has the effect of preventing atherogenesis
.
Vanadium can promote tooth mineralization, prevent dental caries, and reduce the content of cholesterol in serum