Turn off the "switch" and eat more than fat

eat too oily, too sweet easy to make people fat, but "hold your mouth" and talk about how easy? How can you enjoy your food with confidence and keep fit? A new animal experiment conducted by German researchers has found that "turning off" a protein that regulates lipid metabolism can make mice eat less fat.
researchers at the Max Planck Institute in Germany and other institutions found that when mice gained weight through a high-fat diet, a certain length of ceramide molecules accumulated in the liver, which is synthesized by two proteins, ceramide synthase 5 and ceramide synthase 6. Ceramide is an intermediate metabolite of lipids that play an important role in biosynthesis and can promote cell metabolism.
experiments showed that if "off" ceramide synthase 6, so that it does not work, obese mice although continue to eat a high-fat diet, the liver did not have fat accumulation, weight also decreased, the body's sugar metabolism also improved;
further studies have found that ceramide synthase 6 regulates levels of ceramide in mitochondrials. Mitochondrials are a source of energy for cells. The researchers speculate that a high-fat, high-sugar diet is likely to lead to weight gain, possibly due to the volume of ceramide mitochondrials synthesized by ceramide synthase 6 and long-term inhibition of mitochondrial function.
mechanism may also apply to humans, but further research is needed, the researchers said. The findings have been published in the American journal Cell.