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    Home > Biochemistry News > Biotechnology News > Twist Bioscience launches 96-plex library preparation kit for low-depth, high-throughput next-generation sequencing

    Twist Bioscience launches 96-plex library preparation kit for low-depth, high-throughput next-generation sequencing

    • Last Update: 2022-01-25
    • Source: Internet
    • Author: User
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    Twist Bioscience today announced the launch of the Twist 96-Plex Library Prep Kit, an efficient and economical next-generation sequencing (NGS) prep kit
    .
    Recently, new approaches to sequencing-based genotyping (GBS) have unlocked the potential of NGS to not only improve data quality and yield, but also significantly improve laboratory processes and reduce sample preparation costs

    .

    Matt Huentelman, associate professor of neurogenomics at the Translational Genomics Institute (TGen), said: "Using the 96-plex library prep kit, we were able to identify a statistically significant inheritance in Westie lung disease that was previously missed by microarray technology.
    Association.

    Westie lung disease is a canine model of human idiopathic pulmonary fibrosis (IPF)
    .
    "

    Sri Kosuri, founder and CEO of Octant, commented: "We need a reliable, scalable, and low-touch method to verify complete plasmid sequences.
    .
    .
    ideally, one that does not require extensive human and Capital approach

    .
    We found the Twist 96-plex library prep kit!"

    From a time and cost perspective, library preparation is a major bottleneck in the sequencing pipeline
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    By pre-multiplexing up to 960 samples, combined with best-in-class enzymes and optimized oligonucleotide and buffer conditions, the Twist 96-plex library prep kit (formerly iGenomX's RIPTIDE) saves time in late-stage reactions required reagent volume and reduce manual processing time per sample

    .
    Compared to microarrays, the Twist 96-plex library preparation kit can bring more complete genetic information, improve the statistical power of genotyping studies, and allow researchers to obtain deeper biological Learn insights

    .

    "The genotyping enabled by the 96-plex library prep kit is a major advance over microarrays," said Associate Professor Ali Torkamani, Director of Genomics and Genome Informatics at the Scripps Translational Research Institute, part of the Scripps Research Institute
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    This approach provides markers across the genome at higher densities and at significantly lower cost

    .
    "

    Dr.
    Emily M.
    Leproust, CEO and Co-Founder of Twist Bioscience, said: "The Twist 96-plex Library Prep Kit includes a robust PCR-like workflow for ultra-high-throughput library construction, allowing customers to utilize low-volume sequencing data to complete high-quality genotyping across the entire genome

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    Following the acquisition of iGenomX, we 'Twistified' the product, which we believe will help customers conduct studies with hundreds to thousands of samples, whether Screening the traits of seeds is also to verify the sequence of plasmid colonies

    .

    About Twist Bioscience

    Twist Bioscience is a leading and fast-growing synthetic biology and genomics company developing disruptive DNA synthesis platforms to advance the industrialization of bioengineering
    .
    The platform's core patented technology enables a new way of making synthetic DNA by "writing" DNA on a silicon chip

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    Twist is leveraging its unique technology to manufacture a broad range of products based on synthetic DNA, including synthetic genes, next-generation sequencing (NGS) preparation tools, and antibody libraries for drug discovery and development

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    Twist is also pursuing longer-term opportunities in the digital storage of DNA data and the exploration of biologics

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    Twist's products are used in a wide range of industries including healthcare, industrial chemicals, agriculture and academic research

    .

    Legal Notice Regarding Forward-Looking Statements

    This press release contains forward-looking statements
    .
    All statements other than historical facts, including, but not limited to, expected cost savings resulting from the use of the Twist 96 Multiplex Library Prep Kit, are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and are a reflection of management Forward-looking statements of current beliefs and expectations

    .
    Such forward-looking statements involve known and unknown risks, uncertainties and other important factors that may cause Twist Bioscience's actual results, performance or achievements to be material to any future results, performance or achievements expressed or implied by the forward-looking statements sexual differences

    .
    These risks and uncertainties include risks and uncertainties in the ability to attract new customers and retain and increase sales to existing customers; rapidly changing technologies and extensive competition in the synthetic biology field may make products being developed by Twist Bioscience Obsolescence or uncompetitiveness; retention of employees of the acquired company, and Twist Bioscience's ability to successfully integrate the acquired company and realize the expected benefits, third parties accuse Twist Bioscience of infringing or seeking to invalidate patents or proprietary rights risks; and the risk that Twist Bioscience's proprietary rights may not be sufficient to protect its technology

    .
    For a further description of the risks and uncertainties that could cause actual results to differ from these forward-looking statements, as well as risks associated with Twist Bioscience's general business, please see Twist Bioscience's filing with the Securities and Exchange Commission on November 23, 2021 The risk factors listed in the Annual Report on 10-K and subsequent SEC filings

    .
    Any forward-looking statements contained in this press release speak only as of the date of this press release, and Twist Bioscience expressly disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise

    .


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