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On March 15 , 2022 , PNAS , the Proceedings of the National Academy of Sciences, published online the research paper Global genomic instability caused by reduced expression of DNA polymerase ε in yeast in which Zhang Ke , a distinguished researcher at the Institute of Microbiology, School of Life Sciences, Zhejiang University, is the first author .
The replication of eukaryotic genome requires at least three core DNA polymerases , Polα , Polε and Polδ .