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Yimaitong compiles and organizes, please do not reprint without authorization
.
Introduction: When asked about the difference between type 1 diabetes and type 2 diabetes, "absolute beta cell deficiency", "lifelong insulin dependence", and "less than 5% of the total number of diabetic people" will be the answers of many people, but the number of 5% is not It cannot accurately describe the prevalence of type 1 diabetes, but it conceals the huge differences between different countries/regions, income levels, and age groups
.
On October 2nd, a worldwide research on type 1 diabetes was published in the journal Diabetologia (impact factor: 10.
122), which filled the gaps in the understanding of type 1 diabetes
.
Type 1 diabetes that has been "neglected" is behind the shortened life span of more than 10 years.
Diabetes is one of the four non-communicable diseases recognized by the WHO
.
Although it includes type 1 diabetes and type 2 diabetes, it has received more attention due to its large proportion of type 2 diabetes, the risk factors for various diseases and the greater burden it brings
.
Previous studies have estimated that type 1 diabetes accounts for about 5%-10% of overall diabetes, but this statement is usually based on data from the Nordic population (the incidence and prevalence of type 1 diabetes in this population is usually the highest in the world Of)
.
And the current data on the incidence and prevalence of type 1 diabetes is limited (especially for the adult population)
.
In short, compared with type 2 diabetes, type 1 diabetes has been overlooked to a certain extent
.
The emergence of insulin has saved hundreds of millions of patients with type 1 diabetes, but it does not mean that the health problems have been completely resolved
.
Research based on a large sample of European populations shows that the life expectancy of type 1 diabetes patients is compared with that of the general population: ➤Diagnosed at the age of 20: Reduced by about 11 years and 13 years for men and women; ➤Diagnosed before the age of 10: Reduced by about 14 years for men and women, respectively Years and 18 years
.
It is reasonable to speculate that patients living in low-income countries may be worse off due to the lack of access to the same medical care support
.
Type 1 diabetes accounts for about 2% of the total cases, and there are huge differences between countries, less than 1% in China.
The study analyzed the incidence/prevalence of type 1 diabetes in all age groups in the world in 2017, showing that type 1 diabetes is more important than diabetes worldwide The proportion of total cases ranges from less than 1% in some Pacific countries to more than 15% in Nordic countries, and there are huge differences between different countries/regions
.
In addition, although the proportion of patients with onset age <15 years old is the largest (42%), there are still up to 35.
0% and 17.
4% of type 1 diabetes patients who have the onset of type 1 diabetes between the ages of 15-39 and 40-64
.
As far as the status quo is concerned, 43% of type 1 diabetes patients are middle-aged (40-64 years old)
.
This item of data reminds us that for type 1 diabetes, the clinical focus cannot be limited to children/adolescents
.
The richer the country, the higher the incidence of type 1 diabetes? The study found that the estimated number of people with type 1 diabetes in 2017 was 234,710 (Table 1)
.
Although high-income countries (HICs) account for only 17% of the global population, the incidence of type 1 diabetes is as high as 49%.
The reasons behind this need to be analyzed in depth
.
Note: LAC, Latin America and the Caribbean; NA, North America Figure 1 Age distribution of new type 1 diabetes patients Table 1 Type 1 diabetes incidence/prevalence Note: LAC, Latin America and the Caribbean; NA, North America
.
In 2017, there were more than 9 million type 1 diabetes patients in the world, with the highest prevalence rate in North America and the lowest in Asia.
In 2017, the total number of patients with type 1 diabetes in the world is estimated to be 9,004,610 (Table 1), and the age is mainly concentrated in the middle-aged population between 40-64 years old.
➤0-14 age group: 6%; ➤15-39 age group: 35%; ➤40-64 age group: 43%; ➤≥65 age group: 16 %
.
Figure 2 The age distribution of existing type 1 diabetes patients (2017) In addition, although high-income countries (HICs) account for only 17% of the global population, the proportion of patients with type 1 diabetes is as high as 52%, with upper middle income Countries (UMICs), low-middle-income countries (LMICs) and low-income countries (LIC) accounted for 19%, 27%, and 2%, respectively
.
After standardizing age, the prevalence of type 1 diabetes in high-income countries, upper-middle-income countries, low-middle-income countries, and low-income countries are 3.
27/1000, 1.
77/1000, 0.
57/1000, and 0.
28/1000, respectively
.
Divided by country/region: After age standardization, the highest prevalence of type 1 diabetes is North America (4.
4/1000), followed by Oceania (3.
4/1000) and Europe (3.
0/1000), and the lowest is Africa (0.
8 /1000) and Asia (0.
6/1000)
.
The focus of type 1 diabetes should not be limited to children/adolescents.
The author pointed out that in contrast to the rapid increase in the number of type 2 diabetes, type 1 diabetes, which accounts for a relatively small proportion, is difficult to attract people's attention (this study estimates that there are about 9 million 1 Type-type diabetes patients, accounting for about 2% of the total cases of diabetes), but the loss of life span caused by the latter also requires attention
.
Although the clinic attaches great importance to the diagnosis and treatment of type 1 diabetes in children/adolescents, studies have found that up to 43% of patients are actually concentrated in the 40-64 age group.
"Does the attention need to be redistributed?" Maybe It is also a question that needs to be considered in the clinic
.
In addition, there are huge differences in the incidence and prevalence of type 1 diabetes between different countries/regions and income levels
.
The prevalence of type 1 diabetes in high-income countries is approximately 10 times that of low-income countries
.
The age-standardized prevalence rate is highest in North America (4.
4/1000) and lowest in Asia (0.
6/1000)
.
According to WHO, IDF and the results of this study, the proportion of type 1 diabetes in different populations varies greatly
.
For example, type 1 diabetes in China accounts for less than 1% of all diabetes, while in the United Kingdom and Finland, the proportions reach 8.
6% and 17%
.
In short, this study may help different countries to formulate medical and health care measures according to local conditions to better meet the needs of patients with type 1 diabetes at all stages of their life course
.
Yimaitong compiled and compiled from: Green, A.
,Hede,SM,Patterson,CC et al.
Type 1 diabetes in 2017: global estimates of incident and prevalent cases in children and adults.
Diabetologia (2021).
https://doi .
org/10.
1007/s00125-021-05571-8
.
Introduction: When asked about the difference between type 1 diabetes and type 2 diabetes, "absolute beta cell deficiency", "lifelong insulin dependence", and "less than 5% of the total number of diabetic people" will be the answers of many people, but the number of 5% is not It cannot accurately describe the prevalence of type 1 diabetes, but it conceals the huge differences between different countries/regions, income levels, and age groups
.
On October 2nd, a worldwide research on type 1 diabetes was published in the journal Diabetologia (impact factor: 10.
122), which filled the gaps in the understanding of type 1 diabetes
.
Type 1 diabetes that has been "neglected" is behind the shortened life span of more than 10 years.
Diabetes is one of the four non-communicable diseases recognized by the WHO
.
Although it includes type 1 diabetes and type 2 diabetes, it has received more attention due to its large proportion of type 2 diabetes, the risk factors for various diseases and the greater burden it brings
.
Previous studies have estimated that type 1 diabetes accounts for about 5%-10% of overall diabetes, but this statement is usually based on data from the Nordic population (the incidence and prevalence of type 1 diabetes in this population is usually the highest in the world Of)
.
And the current data on the incidence and prevalence of type 1 diabetes is limited (especially for the adult population)
.
In short, compared with type 2 diabetes, type 1 diabetes has been overlooked to a certain extent
.
The emergence of insulin has saved hundreds of millions of patients with type 1 diabetes, but it does not mean that the health problems have been completely resolved
.
Research based on a large sample of European populations shows that the life expectancy of type 1 diabetes patients is compared with that of the general population: ➤Diagnosed at the age of 20: Reduced by about 11 years and 13 years for men and women; ➤Diagnosed before the age of 10: Reduced by about 14 years for men and women, respectively Years and 18 years
.
It is reasonable to speculate that patients living in low-income countries may be worse off due to the lack of access to the same medical care support
.
Type 1 diabetes accounts for about 2% of the total cases, and there are huge differences between countries, less than 1% in China.
The study analyzed the incidence/prevalence of type 1 diabetes in all age groups in the world in 2017, showing that type 1 diabetes is more important than diabetes worldwide The proportion of total cases ranges from less than 1% in some Pacific countries to more than 15% in Nordic countries, and there are huge differences between different countries/regions
.
In addition, although the proportion of patients with onset age <15 years old is the largest (42%), there are still up to 35.
0% and 17.
4% of type 1 diabetes patients who have the onset of type 1 diabetes between the ages of 15-39 and 40-64
.
As far as the status quo is concerned, 43% of type 1 diabetes patients are middle-aged (40-64 years old)
.
This item of data reminds us that for type 1 diabetes, the clinical focus cannot be limited to children/adolescents
.
The richer the country, the higher the incidence of type 1 diabetes? The study found that the estimated number of people with type 1 diabetes in 2017 was 234,710 (Table 1)
.
Although high-income countries (HICs) account for only 17% of the global population, the incidence of type 1 diabetes is as high as 49%.
The reasons behind this need to be analyzed in depth
.
Note: LAC, Latin America and the Caribbean; NA, North America Figure 1 Age distribution of new type 1 diabetes patients Table 1 Type 1 diabetes incidence/prevalence Note: LAC, Latin America and the Caribbean; NA, North America
.
In 2017, there were more than 9 million type 1 diabetes patients in the world, with the highest prevalence rate in North America and the lowest in Asia.
In 2017, the total number of patients with type 1 diabetes in the world is estimated to be 9,004,610 (Table 1), and the age is mainly concentrated in the middle-aged population between 40-64 years old.
➤0-14 age group: 6%; ➤15-39 age group: 35%; ➤40-64 age group: 43%; ➤≥65 age group: 16 %
.
Figure 2 The age distribution of existing type 1 diabetes patients (2017) In addition, although high-income countries (HICs) account for only 17% of the global population, the proportion of patients with type 1 diabetes is as high as 52%, with upper middle income Countries (UMICs), low-middle-income countries (LMICs) and low-income countries (LIC) accounted for 19%, 27%, and 2%, respectively
.
After standardizing age, the prevalence of type 1 diabetes in high-income countries, upper-middle-income countries, low-middle-income countries, and low-income countries are 3.
27/1000, 1.
77/1000, 0.
57/1000, and 0.
28/1000, respectively
.
Divided by country/region: After age standardization, the highest prevalence of type 1 diabetes is North America (4.
4/1000), followed by Oceania (3.
4/1000) and Europe (3.
0/1000), and the lowest is Africa (0.
8 /1000) and Asia (0.
6/1000)
.
The focus of type 1 diabetes should not be limited to children/adolescents.
The author pointed out that in contrast to the rapid increase in the number of type 2 diabetes, type 1 diabetes, which accounts for a relatively small proportion, is difficult to attract people's attention (this study estimates that there are about 9 million 1 Type-type diabetes patients, accounting for about 2% of the total cases of diabetes), but the loss of life span caused by the latter also requires attention
.
Although the clinic attaches great importance to the diagnosis and treatment of type 1 diabetes in children/adolescents, studies have found that up to 43% of patients are actually concentrated in the 40-64 age group.
"Does the attention need to be redistributed?" Maybe It is also a question that needs to be considered in the clinic
.
In addition, there are huge differences in the incidence and prevalence of type 1 diabetes between different countries/regions and income levels
.
The prevalence of type 1 diabetes in high-income countries is approximately 10 times that of low-income countries
.
The age-standardized prevalence rate is highest in North America (4.
4/1000) and lowest in Asia (0.
6/1000)
.
According to WHO, IDF and the results of this study, the proportion of type 1 diabetes in different populations varies greatly
.
For example, type 1 diabetes in China accounts for less than 1% of all diabetes, while in the United Kingdom and Finland, the proportions reach 8.
6% and 17%
.
In short, this study may help different countries to formulate medical and health care measures according to local conditions to better meet the needs of patients with type 1 diabetes at all stages of their life course
.
Yimaitong compiled and compiled from: Green, A.
,Hede,SM,Patterson,CC et al.
Type 1 diabetes in 2017: global estimates of incident and prevalent cases in children and adults.
Diabetologia (2021).
https://doi .
org/10.
1007/s00125-021-05571-8