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.
Five years after the diagnosis of type 2 diabetes, what is the proportion of diabetic retinopathy, and what are the risk factors and protective factors? Recently, a study published in the journal Diabetes care aims to evaluate the occurrence of proliferative diabetic retinopathy (PDR), traction retinal detachment (TRD) and neovascular glaucoma (NVG) in patients 5 years after the diagnosis of type 2 diabetes Rate and risk factors
.
Scholars from the University of Southern California, Keck School of Medicine in Los Angeles, William S.
Gange and other scholars analyzed the data of newly diagnosed type 2 diabetes patients ≥18 years old from the 2007-2015 US National Business Claims Database
.
Calculate the incidence of PDR, TRD and NVG 5 years after the diagnosis of type 2 diabetes, and use multivariate logistic regression analysis to test different variables
.
Five years after the diagnosis of type 2 diabetes, 1.
74% of patients developed PDR.
Five years after the initial diagnosis of type 2 diabetes, 1.
74% (1249 of 71,817 patients) of patients developed PDR, 0.
25% of patients developed TRD, and 0.
14% Of patients developed NVG
.
➤Risk factors: insulin use (OR 3.
59, 95%CI 3.
16-4.
08), maximum HbA1c> 9% (OR 2.
10, 95%CI 1.
54-2.
69), kidney disease (OR 2.
68, 95%CI 2.
09-3.
42), Peripheral circulatory disorders (OR 1.
88, 95%CI 1.
25-2.
83), neurological diseases (OR 1.
62, 95%CI 1.
24-2.
11), older age at diagnosis (65-74 years old, OR 1.
62, 95%CI 1.
28-2.
03) It was determined as a risk factor for PDR after 5 years
.
➤Protection factors: younger age at diagnosis (18-23 years old, OR 0.
46, 95%CI 0.
29-0.
74), medical insurance (OR 0.
60, 95%CI 0.
70-0.
76), obesity (OR 0.
72, 95%CI 0.
59-0.
87) and smoking (OR 0.
84, 95% CI 0.
70-1.
00) were identified as protective factors
.
Research Implications Some patients with type 2 diabetes develop PDR and other neovascular sequelae within the first 5 years after being diagnosed with type 2 diabetes
.
Intensified screening and early intervention may benefit these patients
.
Yimaitong compiled and compiled from: William S.
Gange, Jennifer Lopez, Benjamin Y.
Xu, et al.
Epidemiology/Health Services Research Incidence of Proliferative Diabetic Retinopathy and Other Neovascular Sequelae at 5 Years Following Diagnosis of Type 2 Diabetes[J].
Diabetes Care 2021 Nov; 44(11): 2518-2526.
https://doi.
org/10.
2337/dc21-0228
.
Five years after the diagnosis of type 2 diabetes, what is the proportion of diabetic retinopathy, and what are the risk factors and protective factors? Recently, a study published in the journal Diabetes care aims to evaluate the occurrence of proliferative diabetic retinopathy (PDR), traction retinal detachment (TRD) and neovascular glaucoma (NVG) in patients 5 years after the diagnosis of type 2 diabetes Rate and risk factors
.
Scholars from the University of Southern California, Keck School of Medicine in Los Angeles, William S.
Gange and other scholars analyzed the data of newly diagnosed type 2 diabetes patients ≥18 years old from the 2007-2015 US National Business Claims Database
.
Calculate the incidence of PDR, TRD and NVG 5 years after the diagnosis of type 2 diabetes, and use multivariate logistic regression analysis to test different variables
.
Five years after the diagnosis of type 2 diabetes, 1.
74% of patients developed PDR.
Five years after the initial diagnosis of type 2 diabetes, 1.
74% (1249 of 71,817 patients) of patients developed PDR, 0.
25% of patients developed TRD, and 0.
14% Of patients developed NVG
.
➤Risk factors: insulin use (OR 3.
59, 95%CI 3.
16-4.
08), maximum HbA1c> 9% (OR 2.
10, 95%CI 1.
54-2.
69), kidney disease (OR 2.
68, 95%CI 2.
09-3.
42), Peripheral circulatory disorders (OR 1.
88, 95%CI 1.
25-2.
83), neurological diseases (OR 1.
62, 95%CI 1.
24-2.
11), older age at diagnosis (65-74 years old, OR 1.
62, 95%CI 1.
28-2.
03) It was determined as a risk factor for PDR after 5 years
.
➤Protection factors: younger age at diagnosis (18-23 years old, OR 0.
46, 95%CI 0.
29-0.
74), medical insurance (OR 0.
60, 95%CI 0.
70-0.
76), obesity (OR 0.
72, 95%CI 0.
59-0.
87) and smoking (OR 0.
84, 95% CI 0.
70-1.
00) were identified as protective factors
.
Research Implications Some patients with type 2 diabetes develop PDR and other neovascular sequelae within the first 5 years after being diagnosed with type 2 diabetes
.
Intensified screening and early intervention may benefit these patients
.
Yimaitong compiled and compiled from: William S.
Gange, Jennifer Lopez, Benjamin Y.
Xu, et al.
Epidemiology/Health Services Research Incidence of Proliferative Diabetic Retinopathy and Other Neovascular Sequelae at 5 Years Following Diagnosis of Type 2 Diabetes[J].
Diabetes Care 2021 Nov; 44(11): 2518-2526.
https://doi.
org/10.
2337/dc21-0228
