UK develops vaccine for hypertension

scientists at Protherics, a British pharmaceutical company, have developed a vaccine that suppresseshigh blood pressure, better thandrugs that have side effectsReported that the company has successfully conducted human experiments, and plans to improve the formula for further testing, is expected to be available within five yearsPatients do not have to take drugs for life
the Daily Mail of London reported that protherics, a high blood pressure vaccine developed by Protherics in Cheshire, north-west England, uses a protein from the common shell "cap bet" to attack angiotensin secreted by the liver, which causes arteries to contract and, in turn, lead to higher blood pressureReported that the high blood pressure vaccine will stimulate the body's immune system to attack the hormoneThe vaccine will make it easier for patients to control high blood pressureUntil now, patients have had to rely on taking medications to control high blood pressure, which can cause various side effects and often prompt them to give up taking the drugThe report quoted researcher Andrew Heath as saying: "Vaccination in this way can save thousands of patients from life-threatening complications such asheart
attacks or strokes." "At the same time, the vaccine can help young people with a family history ofheartto control blood pressure to reduce the risk of heart attack."The high blood pressure vaccine requires only three doses, one dose added every six months Protherics, which is expected to go on sale within five years, plans to test it with a new formula that stimulates the immune system 10 times better than the original formula At that time, patients with high blood pressure can be given three consecutive injections in the initial stage of use of the needle, each time at intervals of one or two weeks, after which every six months or a year to ensure that blood pressure is normal Side effects are smaller than oral medicine
Protherics is known to report fewer side effects, but one in ten of the participants complained of short-term discomfort such as influenza Today, some oral medications also use the principle of inhibiting the production of angiotensin to treat high blood pressure, but many patients with hypertension are giving up taking the drug every day because the effect of feeling that the effect of the blood pressure reduction is not obvious Others stopped taking the drug because they didn't want to put up with the side effects of these oral medications For example, "beta-receptor blockers" in such drugs can cause fatigue
, cold , nausea
, diarrhea, and so on Patients taking the drug still cannot completely avoid the risk of stroke British physicians generally welcomed the success of the antihypertensive vaccine Professor McGregor, of the British Blood Pressure Association, said: "High blood pressure is the most important cause of death from heart attacks and strokes in the UK If you have to take a blood pressure control drug , have to take for life, is difficult for some patients to do , find other ways or better ways to try to lower blood pressure without causing side effects , is bound to be extremely popular Dr Mike Nupton, of the British Heart Foundation, said: "In Western European , 1 /
5 or more of heart disease has a history of hypertension, and the antihypertensive vaccine is a way to treat it, but further research is needed "
" Protherics expects the antihypertensive needle to generate 1
20 billion pounds (
$2
3.9 billion a year) in annual revenue s
pent on the drug-lowering needle for clinical use The price of the antihypertensive vaccine is not yet known, but it is estimated that it will not be much more expensive than the usual oral antihypertensive drug that costs only a few cents a day Currently, Swiss company Cytos Bio is also developing a vaccine that fights high blood pressure by stimulating the body's immune system (
reprinted from Guangzhou Daily)