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    Home > Active Ingredient News > Infection > Use this kind of antibiotics for lung infections, never use this kind of cough medicine!

    Use this kind of antibiotics for lung infections, never use this kind of cough medicine!

    • Last Update: 2021-10-23
    • Source: Internet
    • Author: User
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    *Only for medical professionals to read for reference.
    For new drugs, please read the instructions more.
    Foreword, you have not found out that there are often some magical knowledge points hidden in the drug instructions.
    Antibiotics and cough suppressants are commonly used drugs in respiratory medicine.
    If a patient with lung infection is using linezolid to fight the infection, and the patient coughs frequently, the doctor will give dextromethorphan to relieve the cough, can it? If there is a medical dispute, can the doctor retreat or lose the underwear? 1 The love-hate relationship between linezolid and dextromethorphan and the contraindications of linezolid mentioned in the column: Unless the patient's signs and/or symptoms of serotonin syndrome are closely observed, linezolid should not be used for carcinoid Syndrome patients and/or patients using any of the following drugs: serotonin reuptake inhibitors, tricyclic antidepressants, serotonin 5-HT1 receptor agonists (triptan drugs), pethidine Or buspirone
    .

    Oh, I suddenly discovered that when using linezolid to fight infection, even the painkiller pethidine can't be used casually
    .

    Closer to home, many friends may be puzzled, you have said so much, there is a hammer relationship with cough medicine! Not in a hurry, many new drug instructions are comparable to long-length martial arts novels, and it is not easy to understand without three or five years of internal strength! Research over the years has found that the cough suppressant dextromethorphan can exert a serotonergic effect by promoting the release of serotonin and inhibiting its reabsorption
    .

    Linezolid is a reversible, non-selective monoamine oxidase inhibitor
    .

    Therefore, linezolid has potential interactions with adrenergic and serotonin-like drugs
    .

    When linezolid is used in combination with serotonin drugs, symptoms and signs of serotonin syndrome may occur, such as cognitive impairment, high fever, hyperreflexia, and ataxia
    .

    The cough suppressant dextromethorphan has a serotonergic effect.
    Combining it with linezolid may cause serotonin syndrome and should not be used in combination
    .

    Someone may say that the instructions cannot be used without clear writing.
    However, the instructions say: Unless the patient's signs and/or symptoms of serotonin syndrome are closely observed, linezolid should not be used for serotonin drugs.
    Patient
    .

    Can you guarantee that you have time to observe patients closely all day long? You don't write medical records anymore? Are you discharged from the hospital? Also, other cough medicines are safer, why don't you use them? Wait for a bunch of boring questions
    .

    In fact, when dextromethorphan and linezolid are used in combination, serotonin syndrome generally does not occur.
    The instructions say: healthy volunteers have conducted research on potential drug interactions between linezolid and dextromethorphan
    .

    Volunteers were given dextromethorphan (two doses, 20 mg each time, 4 hours apart), with or without linezolid
    .

    The effects of serotonin syndrome (fuzziness, extreme excitement, restlessness, tremor, flushing, sweating, and increased body temperature) were not observed in normal blood pressure volunteers who received dextromethorphan and linezolid
    .

    Even so, it is not recommended to use the instructions, so for safety reasons, try to avoid using these two drugs together
    .

    2 When using levofloxacin to fight infection, you should not use antipyretics and occasionally see some magical instructions from some manufacturers: levofloxacin should be avoided in combination with non-steroidal anti-inflammatory drugs! Picture 1 I was taken aback at the time, the mandibular joint almost dislocated! What are non-steroidal anti-inflammatory drugs? The various antipyretic drugs we usually use, such as aspirin, ibuprofen, acetaminophen, loxoprofen, indomethacin, etc.
    , are all non-steroidal anti-inflammatory drugs! The patient is infected and has a fever.
    It is because of the use of levofloxacin to fight the infection, and even the anti-fever medicine must be avoided.
    Is it to die, or use hormones (steroidal anti-inflammatory drugs) to reduce fever? What the hell? Of course, everyone, don’t worry, many Chinese manuals, the same medicine, different manufacturers, the contraindications are different, and the precautions are different.

    .

    It can be used in conjunction with another manufacturer
    .

    There are also many manufacturers' instructions that do not state that levofloxacin cannot be used in conjunction with non-steroidal anti-inflammatory drugs
    .

    Many manuals like to write: Use this with caution, then use it with caution! This is also avoided, and that is also avoided! Why don't you delist? Summary: For new drugs, read more instructions
    .

    Of course, some manuals are written cautiously, this is also used with caution, and that is also used with caution! This is also avoided, and that is also avoided! There are pits everywhere! Strictly follow the instructions to administer the medicine.
    In case of complicated cases, the doctor may have no medicine available! Once the medicine is used, it will fall into the pit! In addition, the country is rectifying the entertainment industry, rectifying the chaos in education.
    .
    .
    Can you rectify all kinds of weird manuals? The Medical Doctor Station APP "Pandemic Updates" will take you the first time to understand the latest academic progress of the new crown epidemic
    .
    You can view it by pressing and holding the two-dimensional code of the picture below .

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