Vitamin D3 and calcium supplementation did not reduce the risk of cancer in older women

In the United States, about 40% of people will be diagnosed with cancer at some point in their lives Research shows that low-dose vitamin D may increase the risk of cancer, so researchers are also studying whether vitamin D can reduce the risk of cancer Vitamin D3 and calcium supplementation did not reduce the risk of cancer in postmenopausal women four years later than placebo, according to a new study published in JAMA Dr Joan Lappe and colleagues from the Department of nursing and pharmacy of Clayton University randomly divided 2303 women over 55 years old (average age 65 years old) into treatment group (n = 11562000iu / D vitamin D3 and 150 mg / D calcium) and placebo group (n = 1147) for 4 years Researchers examined the proportion of people in the trial (http:// who had various cancers (including non melanoma skin cancer) A total of 109 new cancer cases were found, including 45 cases (3.89%) in the treatment group (vitamin D3 + calcium) and 64 cases (5.58%) in the placebo group The 4 year incidence rate of treatment group and placebo group was 0.042 and 0.060 respectively, and there was no significant difference in incidence rate of breast cancer between two groups Serious treatment-related side effects included kidney stones (16 in the treatment group, 10 in the placebo group) and elevated blood calcium levels (6 in the treatment group, 2 in the placebo group) One of the explanations for the difference between the two groups of patients in all cancer incidence rate is that the baseline vitamin D level of the two groups is higher than the average American population.