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A new study of genetic data from more than 400,000 British adults, published today in Communications Biology, shows a clear association between genetic markers of walking speed and biological age
A causal link between walking speed and leukocyte telomere length (LTL) - biological age A marker of , a lifetime of brisk walking can make a person 16 years younger than their biological age in middle age
That said, the researchers found that faster walking was associated with longer telomeres, not activity levels
Telomeres are "caps" at the end of each chromosome that contain repeats of noncoding DNA that protect chromosomes from damage, much like the caps at the ends of shoelaces prevent shoelaces from unraveling
While the relationship between telomere length and disease is not fully understood, the progressive growth of senescent cells is thought to be responsible for a range of symptoms associated with aging in people
The physical, mental, social and health benefits of walking are well documented, and this study is the first to compare genetic data with participants' self-reported walking speed, actual exercise intensity measurements from wearable activity-tracking devices
"Previous studies on the relationship between walking speed, physical activity and telomere length have been inconsistent and lack high-quality data
Using the UK Biobank, researchers at the University of Leicester have previously demonstrated that just 10 minutes of brisk walking a day can increase life expectancy, with fast walkers living 20 years longer than slow walkers
"Having a slower walking pace is an easy way to identify people at higher risk for chronic disease, unhealthy, aging, and activity intensity may play an important role in optimizing interventions
Tom Yates, the paper's senior author, added: "While we have previously shown that walking speed is a strong predictor of fitness, it was not certain that walking briskly actually leads to better health
Related paper information: https://doi.
