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A recent study published in BMC Infectious Diseases (BMC Infectious Diseases) by researchers from the University of Veterinary Medicine in Hanover, Germany, and the German Defence Force confirmed that this is possible: trained detection dogs can distinguish between patients infected with the new coronavirus (SARS-CoV-2) and those who are not infected by identifying respiratory secretions.
specifically, the researchers collected saliva samples and trachea secretion samples from hospitalized COVID-19 patients who were diagnosed with SARS-CoV-2 positive by nasopharyngeal swabs.
negative control samples were taken from SARS-CoV-2-negative populations who had never had a history of COVID-19 and had no recent history of colds or infections.
the eight detection dogs involved in the study came from the German Defence Forces, and all samples from COVID-19 patients were inactivated with beta-propylene (BPL) to protect them and their trainers from infection during training.
week of training, the dogs were able to distinguish between new crown virus infections and those who were not infected.
on the second day of training, their average detection rate was only 50 per cent, but on the fifth day it increased to 70 per cent and on the seventh day it reached 81 per cent.
a total of 10,388 samples were presented in this controlled double-blind test.
the number of samples shown to each dog during training was 94% overall in a random sample of 1012.
157 correct positive samples and 792 correct negative samples.
total diagnostic sensitivity was 82.63% (95% CI: 82.02-83.24%) and specificity was 96.35% (95% CI: 96.31-96.39%).
8 detection dogs Diagnostic specificity and sensitivity of all detection dogs Compared to bacteria, viruses do not have their own metabolism, so through the host metabolism process, infected human cells release volatile organic compounds, which allow the specific smell of pathogens can be detected by dogs.
, dogs were not thought to be infected with SARS-COV-2.
but recent single infection reports show that dogs can also be infected with SARS-COV-2.
therefore, to use detection dogs as "biological detection weapons," researchers first need to address how to ensure that detection dogs are not infected with SARS-COV-2.
, the researchers say new strategies are being developed to safely display inactived samples.
summary, the study provided a new SARS-CoV-2 screening method, but the results are preliminary and further research is needed to obtain the suitability of the test method in the field.
If this method is enabled, SARS-CoV-2 detection dogs can provide effective and reliable infection detection techniques in a variety of public places and can be used as an alternative or supplement to conventional RT-PCR screening, which is bound to significantly save detection costs and improve detection efficiency.
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