What are the quality requirements for dry particles

Quality requirements for dry granules 1 The content of the main drug shall be determined according to the test method of the finished tablet, and the content of the main drug shall meet the requirements 2 Water content: the water content of dry granules used for traditional Chinese medicine tablet pressing is generally 3% - 5%; the water content of chemical dry granules is 1% - 3%, but some varieties can be excluded 3 The tightness of dry granular material is suitable to be crushed into fine powder with rough feeling by light twisting of fingers It is easy to produce pockmarked surface when the particles are too hard and pressed; it is easy to break into fine powder when the loose particles are crushed, and it is easy to produce top crack when pressing 4 The particle size should be selected according to the weight and diameter of the sheet Large pieces can be pressed with larger particles or small particles, but small pieces must be pressed with smaller particles, otherwise it will cause large difference in sheet weight Tablet pressing particles should be composed of different layers of thickness The proportion of each layer of thickness particles and fine powder is related to drug properties, tablet shape size and mechanical properties In general, 20-30 mesh powder in dry granules should be 20% - 40% If the coarse powder is too much, the weight difference of the pressed tablets will be great, and the phenomenon of loose pieces, cracks, edge and corner hair defects and sticking and punching may be related to the excessive fine powder If you want to know more about granules, please log in our company: < or direct Pharmaceutical Technology Department: < for consultation, our factory will provide you with more professional services!