What are the risk factors of lung cancer? Do you have the risk of lung cancer?

July 10, 2019 / BIOON / - 1.6 million people die of lung cancer every year But if you think these people are just old smokers, you're wrong A new Norwegian Greek study, published in the Lancet's Journal of electronic biomedicine, shows that even if you're younger, even if you don't smoke much, you may be at risk for lung cancer Photo source: http://cn.bing.com researchers from hunt research in Norway investigated 65000 Norwegians aged between 20 and 100, and followed them for 16 years to find out the most dangerous factors A large 2011 study in the United States showed that people who have smoked for more than 30 years can save lives with CT, but 70% of high-risk smokers are not included But CT scan is expensive and can't be used at will, because repeated small doses of radiation can cause damage over time Therefore, researchers want to develop a tool that can identify high-risk groups with high precision 94% of smokers, Oluf Dimitri r? E is an associate professor of clinical and molecular medicine, Tr? Senior oncologist, Department of oncology, Levanger hospital, ndelag county R? E came up with big data from hunt research in Norway to find the right combination of risk factors to predict lung cancer with high accuracy Hunt is a Nord Tr? Ndelag health study, Nord Tr? A large number of health data of most residents in ndelag County in 30 years The database contains information of nearly 120000 people R? E recruited an international research team to study the data After three years of research, the group found that 94% of patients diagnosed with lung cancer were smokers or smokers 6% of non-smokers did not find significant risk factors In addition, they found that 21% of lung cancer cases occurred in people under the age of 55 at the time of Hunter's investigation Of these cases, 36% smoked less than 20 cigarettes a day for less than 20 years Photo source: http://cn.bing.com seven risk factors the results of this study enable the team to determine who is more likely to develop lung cancer among smokers and smokers The researchers screened seven risk factors from 36 variables The team then created a risk calculation that allows you to calculate your risk of lung cancer within six and 16 years This online calculation method is named hunt lung cancer risk model Five of the risk factors are well known: age increases the length of time you smoke (based on the time you smoke 20 cigarettes a day) How many cigarettes a day do you smoke (several cigarettes a day for many years is more harmful than many cigarettes for several years) How long have you quit smoking (the risk will decrease over time) Body mass index (BMI); the lower the BMI, the higher the risk ）Two new factors were added: periodic daily cough (increased risk) How many hours a day are exposed to indoor smoke (increased risk) Fewer CT scans were needed and the team used these seven factors to see if they could predict lung cancer in 45000 people who answered the same questionnaire and were followed for 20 years They all participated in 10 Conor (Norwegian cohort) health studies When they matched people, the team was able to predict with nearly 88% accuracy who would develop lung cancer first Using the model, only 22% of smokers and those who have quit need CT scan to recognize up to 85% of lung cancer patients in the next six years "This method can reduce people's exposure to unnecessary CT scans and maximize the identification of real risk factors "R? E said "This is the first model that can accurately predict lung cancer in light smokers, young people and those who quit smoking years ago "Image source: http://cn.bing.com the United States has implemented CT scan screening for heavy smokers, but once a larger European study is completed, Europe may implement the screening Using this risk calculation method, the future screening of smokers will be more accurate Fortunately, very few people have lung cancer, even in high-risk groups In Hunt's study, those who had smoked had a smoking rate of about 2% over 16 years This data also reflects the fact that in the north, Tr? The population of ndelag is light smoker Usually not a heavy smoker It is important to find an alternative to early detection of lung cancer, and the team is currently working on developing a simple blood test that can be combined with a risk calculation method This can provide better results and further reduce the number of people who need to repeat CT scans [1] are you at risk for lung cancer? 【2】Maria Markaki et al A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types： A HUNT Study， EBioMedicine (2018) DOI： 10.1016/j.ebiom.2018.03.027