What does folic acid know.

Guide: How pregnant and pregnant women should take folic acid!---- Some time ago, an aunt asked why she was taking antihypertensive drugs with folic acid, which was not taken by pregnant women (the patient was taking the antihypertensive drug for Malay acid inaprilic? So today we'll talk about folic acidUsually when it comes to folic acid, we immediately think that pregnant women and pregnant women need to supplement folic acidFolic acid is a water-soluble B vitamin that participates in DNA synthesis, amino acid synthesis and vitamin metabolismFolic acid plays an important role in neurodevelopment and maintenance of normal function of nerve cells, and is an important nutrient necessary for the human bodyThe lack of folate during pregnancy can lead to fetal malformations, including abrain, spina bifida, etcThe study shows that the lack of folic acid in the body in the early stages of pregnancy can cause abnormal development of the central nervous system and is an important risk factor for neural tube malformations, and the scientific and rational addition of folic acid in women during pregnancy can prevent the abnormalities of neural tubes in about 70% of infantsWomen should be given 0.4 mg of folic acid daily during the first 3 months of pregnancy and 3 months after pregnancyFolic acid should be taken under the guidance of a physician or pharmacist, do not increase the dose without authorization, taking too much may lead to zinc deficiencyBut folic acid is not exclusive to pregnant women and pregnant women, some high blood pressure patients also need to take folic acid, just like the aunt mentioned at the beginning of the articlePatients with h-type hypertension are characterized by elevated plasma homocysteine levels, and folic acid plays an important role in plasma homocysteine metabolismIn addition to helping to reduce the concentration of plasma homocysteine, folic acid may also have some effect on the control of blood pressureTherefore, for patients with h-type hypertension, it is recommended to combine antihypertensive drugs with folic acidFrom this point of view, we can also understand that the benefits of folic acid supplementation to the fetus, as described above, are also good for the health of pregnant women and can prevent high blood pressure in pregnancyAs mentioned earlier, folic acid is a very important vitamin in the body, so folic acid should also be supplemented with patients who take drugs that inhibit the synthesis of folic acid in the body, such as those taking methotrexateMethotrexate has been used for rheumatic immunology for decades and is a commondrug for the control of rhicopic spinitis, which plays an anti-inflammatory and immunosuppressive roleHowever, methotrexate inhibits the synthesis of folic acid, so it should be used when taking methotrexate Folic acid reduces the incidence of skin mucosal damage, gastrointestinal adverse reactions, and elevated transaminase caused by methotrexate How much folic acid needs to be added? Guangdong Pharmaceutical Association designated "rheumatic immune disease sybipharmaceutical specifications of the drug expert consensus (one) - rheumatoid arthritis" pointed out that the amount of methotrexate per week less than 15 mg, daily supplement 1 mg folic acid Folic acid supplementation is also needed in anemia patients with a large young red blood cell deficiency due to folate deficiency Folic acid plays an important role in maintaining human growth and development, but not much good, whether pregnant women or other groups must be under the guidance of a physician or pharmacist to correctly supplement folic acid Oh! Ref 1, Birth cohort study on the role of folate supplementation in pregnant women based on inflammatory mechanisms in infants, 2018, Tianjin Medical University Guo Shanchi, different doses of folic acid combined with inapuli treatment of H-hypertension, 2014, Central South University Zhang Xiaomei, Zhou Weihong, Fang Zhizhong Advances in clinical application of folic acid .J Tianjin Pharmacology, 2018,030 (003): 65-69 The Expert Committee on Rheumatism Immunodods of Guangdong Pharmaceutical Association, the Expert Consensus of The Drug Specification smedicine of rheumatic immune diseases (one) - rheumatoid arthritis Chinese Modern Applied Pharmacy, 2017 (3): 139-143.