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Eat some "sugar" and the tumor stops growing? It sounds incredible, but scientists have confirmed this in mice.
results were also published in Nature, a leading international journal.
body, almost every cell relies on a sugar molecule called glucose to "feed."
because cancer cells grow and reproduce rapidly, they need more energy, which means they are more dependent on glucose.
, how do cancer cells change if glucose is low? This is a question that many scientists are curious about.
Despite some studies that have found that limiting glucose can stop cancer cells from growing, researchers have never found a way to stop cancer from developing by limiting glucose without "starving" healthy cells.
fortunate, the sugar the body can use is not just glucose alone.
scientists at Cancer Research UK Beatson Research uk have been investigating how different types of sugar affect cancer cells.
, November 21st, in a new study published in the journal Nature, a team led by Professor Kevin Ryan reveals how a molecule called glycosalysis interferes with the energy supply of cancer cells.
. Preventing tumors from growing glycoucin and glucose belong to the same family and have similar molecular structures.
, professor Ryan and others wanted to know what would happen when the cells that grow in the lab were given mandarin.
studying the internal workings of different types of cancer cells, they found that glycosine does not prevent cells from absorbing glucose, but does.
based on this, scientists speculate that glucotose may interfere with the way cancer cells break down glucose, thereby "delaying" their growth.
, the researchers investigated how feeding meldonic sugar to cancer mice had an effect.
found that pancreatic, skin and lung cancer stopped growing when mice with cancer were given sugar supplements three times a week.
, feeding glycouchese supplements did not appear to have an effect on healthy cells in mice.
. In addition to being treated separately with glycoride, the study also found that when used with chemotherapy, glycoride can promote cancer cell death.
mice who received a combination of "glycoucine and chemotherapy" lived longer than those who were treated separately with "no treatment" or "chemotherapy or sugar". Professor
Ryan said: "Although chemotherapy or glycosis alone can make tumours smaller, when used together, the cancer effect is better and the life span of mice increases."
" 3. For human treatment, Professor Ryan stressed that while supplementation with glycoeol did not significantly affect the weight or health of mice, the study did not provide a detailed analysis of each tissue in the mice and was therefore not certain that glycosain was completely safe.
it's clear that patients can't be recommended for glycosine to fight cancer based on existing findings.
need to be clear that the use of glycodone against cancer has not been validated by clinical trials.
how glycoetorides will play in cancer patients remains to be known.
scientists say they will need to do more research in the lab before entering clinical trials, including investigating the role of glycosain in mice of other cancer types.
, however, while there is still a long way to go, if clinical trials are successful, glycosacanis is expected to help some cancer patients improve their outcomes in the future. Professor
Ryan speculates that for patients, there is little likelihood of direct treatment of cancer with glycoucing sugar, and more likely to supplement existing treatments.
Source: Biological Exploration.