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    Home > Active Ingredient News > Drugs Articles > What is purified water distribution system

    What is purified water distribution system

    • Last Update: 2019-12-20
    • Source: Internet
    • Author: User
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    1、 What is the purified water distribution system? The pure water distribution system is usually composed of pure water storage tank, circulating pump, one or more circulating pipelines and different user points The disinfection method is ozone disinfection, so it needs to be equipped with double plate heat exchanger (cooling effect in summer) or ozone generator, UV lamp and other equipment The size of pure water storage tank should conform to the peak flow of pure water, which has a certain balance with the water production capacity of pure water machine The flow of circulating pump should be greater than the sum of peak flow and return flow Online relevant instruments detect the water quality, once the water quality is lower than the customer's requirements, an alarm can be given 2、 Precautions when selecting purified water distribution system When quoting the price, the distribution system generally does not include the workshop process pipeline system, mainly including the sanitary centrifugal pump, temperature, pressure, flow rate, frequency conversion UV, disinfection method and rack, etc when users select the appropriate distribution system, they need to provide the total length of the workshop pipeline, and the number of water points to facilitate the selection of the appropriate sanitary centrifugal pump power and head In the process of designing the purified water process pipeline in the early stage, first consult the purified water equipment supplier for the selection of process pipeline If the selection is too small, the total return water flow rate and pressure in the workshop will not be reached, and the head loss of the pure water pump will be large If the selection is too large, the power of the pure water pump will be increased, and the comprehensive investment cost will be increased Welcome to consult aitway (Wuhan) Environmental Protection Technology Co., Ltd III key points of purified water distribution system (1) Chinese Pharmacopoeia requires purified water as a sanitary and clean material, and the design and construction of its storage, distribution and transportation system shall be carried out in accordance with the standards of sanitary products (2) the pumps, valves, pipes and pipe joints used in the purified water distribution system in the whole purified water storage and transmission system shall be sanitary type, and the connection mode shall also be card type quick opening type There shall be no dead angle and ponding area in the purified water distribution system, and the average roughness Ra of the internal surface of the parts contacting the purified water shall be ≤ 0.4 μ M (3) Purified water should be recycled, and intermediate storage tank should not be set in the circuit to prevent microbial growth If the purified water needs to be heated or cooled during use, double tube plate heat exchanger should be used and installed as close to the use point as possible (4) In order to prevent the growth of microorganisms on the surface of purified water storage tank, pipeline and filter membrane, ozone generator, ultraviolet disinfection device and pasteurization device shall be set in the purified water transmission and distribution system to disinfect the purified water and monitor it to ensure that the purified water meets the GMP requirements during the distribution and transmission process (5) In the purified water distribution and transmission system, a gas water mixer is added to mix the ozone produced by the ozone (O3) generator with purified water evenly through the mixer, which circulates in the distribution system The purified water is sterilized by ozone (O3) Meanwhile, the trace ozone (O3) dissolved in purified water disinfects the inner wall, valves, pipe joints, etc of the pipeline during the circulation Effectively prevent the growth of microorganisms in the system 3 The disinfection and sterilization of purified water delivery and distribution system is an important means to control microbial pollution in water system The common methods include thermal disinfection, ultraviolet disinfection and chemical disinfection 1 Thermal disinfection method: thermal disinfection includes pure steam sterilization, pasteurization (double tube plate heat exchanger) and superheated water sterilization The ion exchange resin, reverse osmosis, electrodialysis, electric deionization and other devices in the main part of purified water system are generally not suitable for high-temperature disinfection, otherwise aging, crushing or damage will occur 2 UV disinfection is used for disinfection with UV wavelengths of 254nm and 185nm, respectively The UV in the area of 254 μ m in common wavelengths disinfects purified water It can reduce the formation rate of new colonies in the water system, but for plankton, it is only partially effective Through irradiation, it kills no more than 90% of the microorganisms in the water Therefore, its penetration is poor, so its quartz tube should be cleaned regularly 3 Chemical disinfection: there are many kinds of materials for chemical disinfection, including oxygen and chlorine Chlorine oxidants, sodium hypochlorite, calcium hypochlorite, chlorine dioxide, etc.; oxygen oxidants include ozone, hydrogen peroxide, potassium permanganate, etc Ozone is a strong oxidant, which has obvious effect on deodorization, decolorization, sterilization, phenol, cyanogen, iron, manganese and so on Considering the residual problem of chemical disinfection on purified water system, ozone disinfection has been widely used in purified water devices of domestic pharmaceutical plants Halide is an effective disinfectant, but it is difficult to be cleaned out from the water treatment system after use Moreover, only at a higher concentration, such as up to 300 million molecules, can it affect the biofilm But too high concentration of disinfectant will often produce corrosion to the equipment The advantages and disadvantages of both must be weighed when using 4、 The characteristics of purified water transportation and distribution system of our company The design concept of atway purified water distribution system is based on GMP, ISPE engineering guidelines and FDA specifications According to the actual needs of the site, the design is customized and optimized (1) the design and manufacture of purified water transportation and distribution system strictly comply with the requirements of GMP, cGMP and FDA in China; (2) the purified water transportation and distribution system is fully automatic controlled, color touch screen, one button start-up, easy to operate; (3) the purified water transportation and distribution system is integrated into modular design and assembly, convenient to operate, and small to occupy space (4) The purified water transmission and distribution system ensures that the loop is turbulent (flow rate is greater than 1 m / s), and maintains positive pressure in the loop to prevent microorganisms from staying, adhering and breeding on the pipe wall; (5) the purified water transmission and distribution system is designed to drain the whole system completely; (6) the number of vacations of purified water / injection water storage tank is considered in the design (7) The purified water transmission and distribution system monitors the temperature, pressure, flow, conductivity, etc on line, so as to know the operation status of the equipment at a glance; (8) the pump body of the purified water transmission and distribution system is controlled by frequency conversion, which is energy-saving and efficient; (9) the purified water transmission and distribution system of the purified water transmission and distribution system is sterilized periodically at 80 ℃ (10) The components, equipment, pipes and accessories of purified water transmission and distribution system adopt sanitary design; (11) all pipes of purified water transmission and distribution system adopt 316L stainless steel, no dead angle and sanitary chuck connection; (12) multi parameter recorder of purified water transmission and distribution system standard (13) The clean pipeline of the distribution system of purified water transmission and distribution system adopts full-automatic welding (single welding and double-sided forming process), passivation treatment after welding, providing internal mirror photos with test reports; (14) the purified water transmission and distribution system reasonably sets online test points and sampling points, which can meet the needs of maintenance and verification after the system is put into operation 5、 The application of purified water transportation and distribution system is mainly applied to the purified water, injection water pipeline distribution system, pure steam distribution system and clean compressed air pipeline distribution system in pharmaceutical production workshop
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