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    Home > Biochemistry News > Biotechnology News > What is the "Cholinesterase Activity Percentage"?

    What is the "Cholinesterase Activity Percentage"?

    • Last Update: 2020-10-21
    • Source: Internet
    • Author: User
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    : About cholinesterase, I use
    test paper
    method, reference value 20-80U, and today a big husband to give advice, said our report is not standardized! The percentage of cholinesterase activity should be reported, and what mild
    organic
    phosphorus pesticide poisoning is normal 50-7%, moderate poisoning is 30-50%, and severe poisoning is more than 30%. Chronic organophosphate pesticide poisoning whole blood cholinesterase activity is less than 50%. Wait a minute.
    what kind of reporting method is this, and how does the percentage come about?
    my personal opinion is that this is an older classification of the disease. Because I see in the "contemporary internal medicine" the disease classification is as follows:
    (1) mild poisoning: a short period of time exposure to a larger number of organophosphate pesticides, dizziness, headache, patience, vomiting, sweating, chest tightness, blurred vision, weakness and other symptoms, pupils tend to shrink.
    (2) Moderate poisoning: in addition to the more severe symptoms mentioned above, there are muscle beam tremors, narrowing of pupils, difficulty breathing, salivation, bowel pain, diarrhea, gait faltering, clear or blurred consciousness.
    (3) Heavy towel meaning: the extreme reduction of the needle-like, sweaty, respiratory de-secretion significantly increased, breathing difficulties, citrus, pulmonary edema, stool fire ban, convulsions, coma, respiratory paralysis and so on. Brain edema can occur in a small number of patients.
    would like to ask the teachers to answer.
    : Organophosphorus pesticide poisoning is a systemic disease caused by exposure to organophosphorus pesticides with reduced activity of cholinesterase, and the appearance of toxic toxaline, nicotine-like and central nervous system symptoms.
    1, diagnostic principle
    according to the short-term exposure to a large number of organophosphate occupational history, the corresponding clinical performance, combined with the whole blood cholinesterase activity decreased, reference to the working environment of labor health survey data and skin pollution, comprehensive analysis, excluding other diseases, can be diagnosed.
    2, diagnostic and grading standard
    2.1 observational object
    2.1.1 has mild toxic toxaline, nicotine-like symptoms or central nervous system symptoms, while the activity of whole blood cholinesterase is not less than 70%. 2.1.2 There was no clinical manifestation of significant poisoning, and the activity of whole blood cholinesterase was less than 70%.
    2.2 Acute mild poisoning
    After exposure to a relatively large number of organophosphate pesticides in a short period of time, dizziness, headache, nausea, vomiting, sweating, chest tightness, blurred vision, weakness and other symptoms may appear within 24 hours, the pupil may shrink. Whole blood cholinesterase activity is generally 50 to 70%.
    2.3 Acute moderate poisoning
    In addition to the more severe symptoms mentioned above, there are muscle beam tremors, shrinking pupils, mild breathing difficulties, salivation, abdominal pain, diarrhea, gait faltering, clear or blurred consciousness. Whole blood cholinesterase activity is generally 30 to 50%.
    2.4 Acute Severe Poisoning
    In addition to the above symptoms, one of the following conditions can be diagnosed as severe poisoning:
    a. pulmonary edema;
    b. coma;
    c. respiratory paralysis;
    d. cerebral edema;
    whole blood cholinesterase activity is generally less than 30%.
    2.5 late oncercological neuropathy
    2 to 3 weeks after the disappearance of acute severe poisoning symptoms, some cases can appear sensory, motor-type peripheral neuropathy, neuro-electromyogram examination shows neurogenic damage.
    .
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