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    Home > Active Ingredient News > Drugs Articles > What is the difference between a rotary evaporator and short-range distillation?

    What is the difference between a rotary evaporator and short-range distillation?

    • Last Update: 2020-05-28
    • Source: Internet
    • Author: User
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    rotary evaporatoris a device used to effectively remove solvents from the sample through decompression evaporationRotating evaporation and convenient use for the separation of low-boiling solvents (e.gC6 hydrocarbons) from compounds at room temperature and pressure that are solidHowever, if there is a small degree of co-evaporation (co-boiling behavior) and there is sufficient difference between the selected temperature and the boiling point under decompression, then careful application can also remove the solvent from the sample containing liquid compoundsuserotary evaporatorwhen you want to remove the solventThe liquid deposits the film on almost the entire surface of the flaskThe membrane allows for a large surface area and faster evaporation of liquidUse this method of removing large amounts of solvents when you want to remove large amounts of solventsshort-range distillation is commonly used for compounds that are unstable or purifyed at high temperaturesThe advantage is that the heating temperature under decompression can be much lower than the boiling point of the liquid at standard pressure, and the distillate fluid only takes a short distance before condensingA shorter path ensures that very few compounds are lost on the side of the deviceshort-range distillation is almost a rough distillation type, and the reason you don't want to use it is because it doesn't have good separation capacity and is slower than the rotary evaporatorIn other words, short-range distillation is cheaper and does not require a vacuum pump
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