The new crown virus strain that caused the Nanjing epidemic was a delta mutant strain.
According to Bao Changjun, an expert from the Jiangsu Provincial Health Commission's New Coronary Pneumonia Prevention and Control Expert Group and director of the Jiangsu Provincial Center for Disease Control and Prevention, the transmission capacity of the Delta strain has been significantly enhanced, which has doubled the transmission capacity of other strains in the past.
According to information from the National Health and Medical Commission, the current domestic vaccination has exceeded 1.
The author units of the above-mentioned studies are China CDC and Chengdu CDC
Patient A is a 33-year-old Chinese male sailor who returned from India via Kathmandu, Nepal on April 26, 2021.
Patient B is a housewife.
Patient C, a male employee of a cement company, took a different flight from Patients A and B on May 9, 2021.
Epidemiological investigations showed that patient A arrived in Kathmandu, Nepal from New Delhi, India on April 19, patient B arrived in Kathmandu, Nepal from Uttar Pradesh, India on April 21, and patient C had worked in Kathmandu, Nepal before returning home
Patient A was vaccinated with Beijing Biotech's new coronavirus inactivated vaccine on January 25 and February 8, 2021, and patient C was vaccinated with Beijing Kexing's new coronavirus inactivated vaccine on October 19 and November 4, 2020 , Patient B is not vaccinated
On April 27 and May 11, the nasopharyngeal swab samples of 3 patients were sequenced with commercial kits to obtain whole genome sequences of 29858, 29732 and 29877bp in depth and more than 3000X in depth
Patients A, B, and C were transferred to the Chengdu Public Health Clinical Center for isolation treatment on April 26, May 3, and May 10, 2021.
During the isolation treatment of patients A, B, and C, the researchers found three differences between the vaccinated and unvaccinated patients
First, studies have shown that the time from being diagnosed with an infection to being positive for antibodies is shorter for vaccinated patients than for unvaccinated patients
First, studies have shown that the time from being diagnosed with an infection to being positive for antibodies is shorter for vaccinated patients than for unvaccinated patients
Second, the Ct value (Editor's note: the lower the Ct value, the more severe the infection) in the sample of unvaccinated patients seems to be lower than that of the vaccinated patients
Finally, the study also found that vaccinated patients have shorter hospital stays than unvaccinated patients
.
Patient A and patient C were discharged after 21 and 25 days of hospitalization, respectively, and patient B was discharged on June 7 after 36 days
.
Research shows that the vaccine still protects against the "Delta" strain
.
According to previous studies, among the confirmed cases, the proportion of people who have not been vaccinated and those who have not been vaccinated are severely ill or have a serious illness, which is significantly higher than that of people who have been vaccinated
.
Compared with unvaccinated cases, the time from diagnosis to antibody production in vaccinated cases is shorter, the CT value is higher, and the hospital stay is shorter
.
Therefore, experts call on people in other low-risk areas to get vaccinated as soon as possible
.
In the early morning of July 29, Zhang Wenhong, director of the Department of Infectious Diseases at Huashan Hospital affiliated to Fudan University, also posted a microblog to analyze the epidemic situation in Nanjing and the effectiveness of vaccines
.
Zhang Wenhong said that someone can be infected after being vaccinated.
Like this time in Nanjing and last time in Guangzhou, some people were infected after being vaccinated
.
But if there is no vaccine, the number of people infected may be even higher
.
In the end, how effective the vaccine is, ultimately requires real-world prevention and control data
.
This is true internationally, and domestically, it is no exception
.
At present, the vaccination rates in the UK and Israel are close to 70%.
After the recent liberalization, there has been a significant increase in the number of infections, but this increase in incidence no longer causes a run on medical resources, and the fatality rate of the disease has also increased from last year.
The highest 18% dropped to 0.
1% in the most recent week
.
This level is close to the case fatality rate of influenza
.
In the future, vaccination will still not be able to completely control the continuation and recurrence of the epidemic, but if the fatality rate drops to the level of influenza after full liberalization, then the serious consequences of the virus epidemic can be eliminated, or the "new crown" will be eliminated.
The hazard is reduced to the level of seasonal flu through vaccination and the establishment of population immunity in a short period of time
.
If human beings do not have a vaccine, they will learn to get along with such viruses through the gradual establishment of herd immunity, but it will take decades to pay a huge price
.
Zhang Wenhong said, is there any effect of China's vaccines? The recent continuous observation of the inactivated vaccine completed in Chile after the market is medically called a real-world study, and the data is published in the most famous international medical journal, the New England Journal
.
This is a harder test
.
Chile evaluated the protection of the Chinese population of inactivated vaccines from February 2 to May 1 this year.
The cohort includes 10.
2 million Chilean populations.
Among the population vaccinated with 2 doses, Chinese inactivated vaccines the effectiveness of the prevention of new infections crown was 65.
9%, the rate of hospitalization of patients with preventive protection force 8 7.
5 % (95% CI, 86.
7-88.
2), force protection prevention of ICU admission rate was 90.
3%, the protection force of death was 86.
3%
.
The results of Chile's vaccination show that China's inactivated vaccine is highly effective in preventing the severity of COVID-19, hospitalization and death
.
If the goal is to slow down the spread and reduce the fatality rate, it can afford a certain degree of protection, but as the goal of clearing and eradicating the epidemic, it may be a goal that the current vaccine cannot achieve
.
7.
5 Zhang Wenhong concluded, "These data can tell us that in the future, even if each of us is vaccinated, the new crown will still be epidemic, but the degree of epidemic will be reduced, and the mortality rate can be reduced
.
After the opening up, there will be people infected.
In the future, all countries will have to face it.
Yes, vaccines reduce the mortality rate and the spread of diseases, but it is very important that the citizens’ awareness of prevention and control and the strength of the national public health system (including hospitals and disease control) can finally achieve harmony with the virus
.
"
Focus on the new crown pneumonia epidemic
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