echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Antitumor Therapy > When advanced breast cancer is in remission, which treatment works?

    When advanced breast cancer is in remission, which treatment works?

    • Last Update: 2022-10-20
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com


    A team of medical researchers from the United Kingdom and the United States found that a patient with advanced breast cancer was in remission
    by taking cannabinoids and psilocybin while receiving standard chemotherapy.
    The case was published in a paper in the journal Pharmaceutical Science, Policy and Law, and the treatment case is described in detail below
    .


    Cannabinoids and psilocybin


    Cannabinoids are extracts of the narcotic drug cannabis, and psilocybin is a hallucinogenic alkaloid
    extracted from mushrooms.
    In some preclinical studies, cannabinoids and psilocybin have shown antiproliferative, apoptosis, and antiangiogenesis capabilities, but how these compounds work has not yet been elucidated
    .


    Figure 1.
    Potential anti-cancer mechanisms of cannabinoids


    Although there is currently limited clinical evidence for the use of medical cannabis products and hallucinogens for the treatment of cancer, they are safe and effective in reducing cancer-related symptoms and alleviating the side effects of chemotherapy, including anxiety, depression, pain, nausea and vomiting
    .
    There have also been individual reports of self-administered use of medical marijuana helping lung cancer patients to regress
    tumors.


    Did the patient with advanced breast cancer below benefit from these adjuvant treatments? Let's take a look
    .


    Hemp oil and magic mushrooms, do they really work?


    In 2018, a 49-year-old woman presents to the doctor
    because of an abnormality found in a self-examination.
    Imaging tests were performed to confirm invasive ductal carcinoma
    .
    The molecular immunohistochemistry results were ER+, PR-, HER2+, and the BRCA gene mutation was negative
    .
    The bones, liver, and lymph nodes are affected
    .
    Overall imaging findings indicate advanced breast cancer, and the overall treatment expectations are poor
    .


    Immediately after, the patient began standard chemotherapy with targeted drugs for HER2, including pastrozumab, trastuzumab, and docetaxel
    .
    In addition, she also adopted a ketogenic diet (for details on ketogenic diet, please refer to the article on cancer degree).

    In addition, the patient, under the guidance of a therapist, begins to ingest cannabinoids and psilocybinoid
    .


    Figure 2.
    Results of PET-CT imaging before the first round of treatment


    In January 2019, after a few months of overall treatment, tests revealed that all of the patient's tumors had disappeared, doctors speculated that chemotherapy and targeted drugs worked, and it was unclear
    what role the cannabinoids and psilocybin played.
    Since the tumor disappeared, to alleviate the adverse reactions, the patient stopped chemotherapy and chose to continue taking cannabinoids and psilocybin.


    Figure 3.
    PET-CT of bone metastases before and after treatment


    In August, the tumor did not recur and the patient reduced the cannabinoid dose by 50% and stopped psilocybinoid
    .


    In June 2020, a review found that the tumor had
    returned.
    The patient received chemotherapy again and continued to use cannabinoids and psilocybinoids
    .
    Until October 2021, the tumor was in a stable state
    .
    The patient's current condition has not been followed up and is unclear
    .


    revelation


    For the treatment of tumors, researchers are constantly exploring and trying to help patients fight
    the disease in various ways.
    Just like the treatment case selected by the degree of cancer, we currently cannot judge the role of cannabinoids and psilocybin in the treatment, but those treatments that have achieved excellent efficacy are not obtained in such exploration and clinical trials again and again? In future anti-cancer research, whether relevant drugs will be extracted from these substances to achieve miraculous therapeutic effects is something we can continue to pay attention to
    .


    In this case, when the patient is diagnosed and the disease relapses, chemotherapy and targeted therapy
    for HER2 are used first.
    Therefore, whether cannabinoids and psilocybin have a certain auxiliary effect in the treatment process needs more research data to confirm
    .


    In addition, we should pay attention to screening some health products under the banner of anti-cancer and anti-cancer, and do not try them ourselves, so as not to cause damage to the body, and even affect the normal treatment in the later stage, and the gains outweigh the losses
    .


    Cancer, accompany you through every step of the fight against cancer!


    Reference: Rayyan Zafar et al, Raising awareness: The implementation of medical cannabis and psychedelics used as an adjunct to standard therapy in the treatment of advanced metastatic breast cancer, Drug Science, Policy and Law (2022).

    Click below to learn more about our clinical trial programs

    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.