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    Home > Active Ingredient News > Endocrine System > When I was young, I was afraid of the cold and I had broken bones again and again. What is the situation?

    When I was young, I was afraid of the cold and I had broken bones again and again. What is the situation?

    • Last Update: 2021-04-14
    • Source: Internet
    • Author: User
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    *Only for medical professionals to read and refer to the 30th article related to the prevention and treatment of osteoporosis published by Professor Bian Pingda of Zhejiang Provincial People's Hospital in the medical field.

    Sister Yuan, 70, who has suffered five fractures in 20 years, said she was more afraid of cold when she was young, and always wears one more dress than women of the same age.

    After menopause, he became more afraid of cold.
    In the past two years, the degree of cold fear has further increased and lower back pain has occurred.

    During night sleep in winter and spring, even if she wears cotton sweaters and cashmere sweaters, cotton trousers, warm pants, shoulder pads, knee pads and thick socks, Sister Yuan will still feel cold all over her body and pain in her back.
    You must put four hot water bottles on your shoulders, waist, knees and soles of your feet to fall asleep.

    In addition to being afraid of the cold, Sister Yuan also suffered 5 fractures.

    The 47-year-old slipped and fell in the bath, causing a fracture of the left rib; the 50-year-old slipped in the kitchen and caused a fracture of the right rib; the 55-year-old slipped while taking a bath, and the right hip was fractured.
    After lying flat at home for 3 months I barely got up and walked.
    Ten years ago, when I was drying clothes at the window, my left rib hit the edge of the window, and my rib broke again.
    I tripped on the road "speed bar" two years ago, and suffered a fracture of the pelvis and the 11th thoracic vertebra.
    I got out of bed after lying down for more than 4 months.
    .
    .
    In addition to repeated fractures, Sister Yuan also suffered from severe arthritis of the knees.

    Ten years ago, he was unable to walk due to pain in his left knee, and had undergone a total knee replacement on his left in the outer hospital.

    Why did the patient have repeated fractures? Sister Yuan said that she was a premature baby and her mother gave birth to her in July.

    He was born and soon after liberation.
    The family's economic conditions were average, and the nutrition of infants and young children had not kept up, and the physique was weak.

    After entering the perimenopausal period, the failure to actively prevent osteoporosis is one of the main reasons for the repeated fractures of Sister Yuan.

    As we all know, after women enter the perimenopausal period, with the rapid decline of estrogen levels in the body, the activity of osteoclasts increases significantly, and the rapid loss of bone mass occurs [1].

    But more than 20 years ago, middle-aged and elderly women were generally weak in preventing osteoporosis, and Sister Yuan was no exception.

    Failure to receive anti-osteoporosis treatment in time after the fracture is also the main reason for Sister Yuan’s repeated fractures.

    Osteoporosis is a systemic bone disease with decreased bone strength and increased fracture risk [2].

    Once a middle-aged and elderly woman has a fracture, she should be alert to the possibility of osteoporosis and go to the hospital for appropriate examination and treatment in time.

    Although Big Sister Yuan started to fracture repeatedly more than 20 years ago, she chose to lie down at home to recuperate after each fracture, and she never went to a doctor, thus losing the best opportunity to treat osteoporosis.

    How to reduce the risk of recurring fractures in patients.
    Sister Yuan's dual-energy X-ray absorption method after admission to the hospital showed that the bone density of the lumbar spine (L1-L4) was T-value -4.
    0 (see Figure 1), and the total bone density of the left hip was T -The value is -2.
    6.

    Since the patient had suffered multiple fractures, he was diagnosed with severe osteoporosis.

     Figure 1 Sister Yuan’s dual-energy X-ray absorptiometry bone mineral density report.
    Sister Yuan’s serum bone turnover markers showed that the level of the β-specific sequence of the carboxy-terminal peptide of type I collagen was low (146.
    2pg/ml) (see screenshot 2).

    If such patients choose to use anti-bone resorption drugs such as bisphosphonates, the therapeutic effect is poor, so osteogenic therapy should be selected [3].

     Figure 2 Sister Yuan's serum bone turnover marker report After receiving subcutaneous injection of the bone formation drug "teriparatide" for 4 weeks, Sister Yuan clearly felt that her low back pain was relieved, and she was not as afraid of cold as before.

    With the prolonged use of bone formation drugs, Sister Yuan will definitely get better and better! References: [1] Bijelic R, Milicevic S, Balaban J.
    Risk factors for osteoporosis in postmenopausal women[J].
    Med Arch,2017,71(1):25-28.
    [2] Chinese Medical Association Osteoporosis and Branch of Bone Mineral Diseases.
    Guidelines for the diagnosis and treatment of primary osteoporosis (2017)[J].
    Chinese Journal of Osteoporosis and Bone Mineral Diseases, 2017, 10(5): 413-436.
    [3] Bian Ping Da, Shou Zhangxuan.
    The selective application of teriparatide in postmenopausal osteoporosis patients[J].
    Chinese Journal of New Drugs and Clinics, 2016, 35(3): 77-78.
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