When skeletal stem cells encounter puberty-Zhou Bo's group reveals the cellular basis for the transformation of bone growth patterns before and after puberty

On September 8, the international academic journal Cell Stem Cell published online the latest research progress of the Zhou Bo research group of the Center for Excellence in Molecular Cell Science (Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences "Tracing the skeletal progenitor transition during postnatal bone formation"

Zhou Bo’s research group has been committed to the study of stem cell developmental regulation.

Based on the principle of the dual homologous recombinase system developed by Zhou Bin, Zhou Bo's research group realized the simultaneous tracing of growth plate cartilage and Lepr+ bone marrow stromal cells

Exercise is beneficial to bone growth or thickening? In the animal running experiment, Zhou Bo's research team found that long-term running will significantly promote the osteogenic differentiation of growth plate cartilage, but it has no significant effect on Lepr+ bone marrow stromal cells

Researcher Zhou Bo from the Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences is the corresponding author of this article.

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Changes in the properties of skeletal stem cells before and after puberty