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    Home > Biochemistry News > Biotechnology News > Why does Ceres NMN regulate sleep?

    Why does Ceres NMN regulate sleep?

    • Last Update: 2020-09-16
    • Source: Internet
    • Author: User
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    The entry of Ceres NMN into the body into NAD-plus, NAD-and-wake SIRT1 regulates the physiological clock, which can greatly help sleep disorders caused by day and night life reversal or age.
    01 Sleep issues that the world is concerned about Sleep is a physiological need, a spontaneous, reversible periodic state.
    people spend about one-third of their lives in sleep, during which the body's consciousness is temporarily interrupted and the response to external stimuli is reduced, which is also an important part of the body's recovery, information integration and memory consolidation, and plays an important role in human health.
    A survey released by the China Sleep Research Association shows that the rate of insomnia among adults in China is as high as 38.2%, and the proportion is still rising as people's pace of life accelerates and social pressure increases.
    it's worth noting that about 90 percent of people use electronics before they fall asleep at night, and that short-wave light from electronics can affect normal biological rhythms in the body, causing sleep problems.
    02 What exactly is a biological clock? The biological clock is an invisible "clock" in the organism, which in fact refers to the physiological and biochemical activities of various organisms that change periodically over time.
    , for example, the rhythms of physiological indicators such as blood pressure and body temperature in a 24-hour cycle are circadian changes that are generated by the Earth's self-change.
    the rhythmic phenomenon that life on Earth exhibits with the rhythmic movement of the earth is what we usually call the biological clock.
    Image point, the human biological clock as a large-scale factory, then located in the lower chimchos cross the core of the main biological clock is the factory's general command, distributed in the five dirty six-week outer biological clock, like each type of work, each kind of work seems to work different content but consistently listen to the command has a unified pace, steady and down-to-earth development of the rhythm of life.
    03 Consequences of Biological Clock Disorder Numerous studies have found that we share a very similar set of circadian rhythm control mechanisms within our bodies.
    In a day and night, our body temperature, pulse, blood pressure, hormones, oxygen consumption, etc. are changing over time, and some will show a strong periodicity.
    now scientific research has also shown that the biological clock regulates human health.
    if people don't follow the biological clock, they will be less productive and can lead to other complex diseases such as obesity, diabetes, high blood pressure, depression and cancer.
    long-term insomnia or lack of sleep can bring serious harm to the human body.
    Sleep studies show that long-term insomnia can lead to inattention, memory loss, abnormal decision-making, can induce premature aging, high blood pressure, myocardial infarction, hyperlipidemia, obesity and even cancer and other physical diseases, but also cause anxiety, depression, and even hallucinations and other mental symptoms.
    04 the principle of sleep-beneficial NMN is related to the effects of NAD plus, which improves sleep and longevity protein SIRT1.
    acetylase (Sirtuin) has been scientifically proven to fight aging, longevity, and play an important role in a variety of cellular processes, so it is also known as the Longevity Protein.
    sirtuins are found in mammals and consist of 275 amino acids with seven different subsypes (SIRT1-SIRT7).
    SIRT1 is not only good for health and longevity, it also helps set the biological clock in the body.
    , the researchers first monitored the mice's natural activity patterns.
    Usually, mice had a slightly shorter biological clock than 24 hours, about 23.5 hours; mice without SIRT1 in the brain had a slightly longer biological clock, approaching 24 hours; mice with 2 times the normal amount of SIRT1 had a slightly shorter biological clock than normal mice; and mice had a shorter biological clock if SIRT1 levels reached five times their normal level.
    levels of SIRT1 in the brain helped the main biological clock adapt to changes in seasonal sun length, and the biological clock in mice grew closer to 24 hours as they grew older.
    is the length of the biological clock associated with a decrease in SIRT1 levels in the brain? The researchers made a four-hour time difference in mice by suddenly changing the lab's light.
    young mice reset their biological clocks in just two days and adapted to the 'new time zone', while older mice took eight days to regroup.
    further experiments found that young mice with low levels of SIRT1 in the brain needed four days to re-adapt, while older mice with high levels of SIRT1 recovered faster than the average older group.
    suggests that SIRT1 and the ability to reverse jet lag are at least correlated.
    also found that SIRT1 levels in the brain's biological clock were also closely related to other important clock protein levels.
    And our body's NAD plus is an important source of energy to activate the longevity protein, but everyone who knows NAD plus knows that NAD plus molecules are too big to be taken directly from outside the body to absorb, so we can only take NAD plus premedid substance NMN, so that in the body into NAD plus, let NAD plus activate SIRT1, improve our sleep mechanism.
    05 Older people need Cerrito NMN and young people sleep disorders are not the same, the elderly sleep is actually regular, but many older people sleep shorter, wake up in the middle of the night and other characteristics, this is actually a problem of the day and night law, and the lack of NAD plus related: with the age of the person, the oscillator and the main clock NAD plus level drop, SIRT1 level drop, clock gene expression decreased, resulting in a longer cycle, adaptability.
    In this way, supplementing Ceres NMN can adjust the inherent cycle of the physiological clock, so that its adaptability is enhanced, the most direct embodiment is that many elderly people take Ceres NMN after sleep quality improvement, more likely to sleep until dawn.
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