Why is the health of the young population more vulnerable?

In !-- paper, the paper compiles several studies published by scientists to explain why young people are more likely to suffer from certain diseases. Share it with everyone! Pictured: CC0 Public Domain 1 Nat Commun: Why are cancer immunotherapy ineffective in young women? Doi:10.1038/s41467-020-17981-0 Cancer immunotherapy enhances the patient's own immune system's ability to remove tumors on its own, and has broad prospects for some patients.
therapy is not widely available to all patients.
a recent study, researchers at the University of California, San Diego School of Medicine found evidence that could help explain why young and/or female patients are particularly less likely to respond to certain types of cancer immunotherapy.
The findings suggest that because young and female patients often have stronger immunity to better remove tumor cells, the cells left behind are initially less undetectable to the immune system, making certain types of immunotherapy ineffective, " the findings, published in the international journal Nature Communications, suggest.
Cancer cells or infected cells express molecular markers that tell the immune system to remove them before the problem gets out of hand, and the main tissue compatible complex (MHC) is distributed on the surface of most cells in the body, with an antigen marker, and presented to T cells that constantly examine damaged or infected cells, so that tumor cells carry large numbers of mutations, so that the immune system can detect and eliminate them.
: Obesity may increase the risk of death in PATIENT-19 patients, especially young male patients doi:10.7326/M20-3742, a In a study published in the international journal Annals of Internal Medicine, scientists from Kaiser Medical Center in Southern California and others found a significant association between the risk of death or BMI in patients with COVID-19, and that the association did not depend on obesity-related diseases and other potential disruptive factors.
the results of this paper show that there is a significant association between the mortality rate of COVID-19 and the higher BMI in both young and male patients, but this association does not appear to exist in female patients and the elderly population.
the study, researchers analyzed the medical records of more than 6,900 COVID-19 patients recruited to The Kaiser Health System in Southern California between February and May 2020 to determine the association between obesity and COVID-19 deaths; Infarction and chronic lung disease or kidney disease, which are themselves risk factors for poor prognosis in patients with COVID-19, in addition, the study also took into account the time patients were tested for SARS-CoV-2, and found that within 21 days of being diagnosed with COVID-19, the mortality rate in the higher weight group was four times higher than in the normal weight group.
: Shock! Just one night's sleep increases young men's risk of Alzheimer's disease Doi:10.1212/WNL.000000000008866 In the study, scientists from Uppsala University found that when young men did not sleep for just one night, their blood levels of tau protein, a key biomarker of Alzheimer's disease, were higher than when they had enough sleep at night.
Tau protein is a special protein in neurons that forms entanglements and accumulates in the brains of Alzheimer's patients, and begins to form in the brain before symptoms of the disease appear; previous studies of older people have shown that lack of sleep increases levels of tau protein in the body's cerebrospinal fluid, and head trauma increases the concentration of circulating tau protein in the blood.
M.D. Jonathan Cedernaes points out that many of us will get less sleep at some stage in our lives due to jet lag, staying up late to complete projects, shift work, overtime or job instability, and in this study we found that it is young, healthy people who get one night's sleep that also increases levels of tha protein in their body's blood, suggesting that over time, lack of sleep may have a detrimental effect on the health of the body.
is the incidence of colorectal cancer getting younger and younger? News read: Colorectal cancer increase in younger adults: What can be the cause? Today, colorectal cancer remains the leading source of cancer incidence and death in the United States, with 145,600 new cases of colorectal cancer and 510.2 million deaths in the United States in 2019, making colorectal cancer the fourth leading cancer type diagnosed in the United States and the second leading cause of cancer death.
The overall incidence and mortality of colorectal cancer has been declining since the mid-1980s, mainly due to increased preventive screening of the population and more effective diagnostic and treatment strategies, as well as awareness of risk factors and disease symptoms.
unfortunately, however, the incidence of colorectal cancer may not be the case among young people, and the incidence and mortality rates of colorectal cancer patients under the age of 50 have been increasing over the past 30 years.
A 2017 study by researcher Rebecca Siegel and colleagues found that while colorectal cancer patients make up only a small fraction of the total number of cancer patients in the younger population, the incidence of colorectal cancer in this group is increasing at an alarming rate;
!-- / ewebeditor: page -- !-- webeditor: page, title-- watch out! COVID-19 seriously affects the sexual and reproductive health of young people! Doi:10.1363/psrh.12151 A new study published in the international journal Perspectives on Sexual and Reproductive Health, conducted by researchers from Columbia University's Melman School of Public Health and Rutgers University, shows that limited social distance and access to contraception and abortion care during the COVID-19 pandemic are affecting sexual and reproductive health in adolescents and young people.
researchers explored these challenges and how to properly handle peer relationships and relationships.
For teenagers and young people, dramatic changes include school closures, the possibility of more time with their families, the interruption of the normal track of increasing independence, and, for many, very limited or no physical contact with sexual and romantic partners.
The authors note that while the pandemic may lead to reduced sexual opportunities for some young people, the disruption of contraception and abortion can be extremely serious for adolescents and young adults, who are still able to maintain physical close contact with their partners during the pandemic.
"The good news is that some services, including access to multiple forms of contraception and testing and treatment for sexually transmitted diseases, can be done through telemedicme," said Leslie Kantor, a professor and director of the Department of Urban Global Public Health at Rutgers University.
if telemedicin remains as widespread as it was during the coronavirus pandemic, young people's access to sexual and reproductive health care may actually improve.
" However, Kantor and his colleagues say the lack of privacy and confidentiality -- which many adolescents and young people are experiencing while living with their families -- hinders their access to the necessary sexual and reproductive health care.
picture source: JAMA Network Open: Watch out! The obesity epidemic will slowly shift cancer to the younger population! doi:10.1001/jamanetworkopen.2019.9261 In a recent study published in the international journal JAMA Network Open, scientists from Case Western Reserve University analyzed data on disease rates across the country from 2000 to 2016 and found that Obesity-related cancers (OACs, obesity-associated cancers) are being transferred to the younger population, generally with higher rates of diagnosis among people over 65 years of age, most notably in non-Hispanic black and Hispanic women and men, and in some cases by 200-400 percent.
The data in this paper comes from more than 6 million cancer cases in the Monitoring Epidemiology and End Results Program (SEER) database, and researcher Siran Koroukian says we're surprised that obesity-related cancers have now spread to people aged 20-49. But the most significant was the 50-64 age group; the number of people aged 50-64 increased by nearly 52 percent over the study period, so the absolute number of people affected was significant, with a significant increase in the proportion of black and Hispanic women and men who did not hispanic.
7 Be vigilant! Smoking e-cigarettes can damage the fertility of young women! NEWS READ: The use of e-cigarettes may affect fertility and pregnancy outcomes, according to a study published in the journal Journal of the Endocrine Society.
many young people and pregnant women are using e-cigarettes as a safer alternative to smoking, we know little about their impact on fertility and pregnancy outcomes.
e-cigarettes are increasing the use of tobacco products by adolescents.
according to the Centers for Disease Control and Prevention, the number of high school students using e-cigarettes rose from 2.1 million in 2017 to 3.6 million in 2018, a difference of about 1.5 million from the number of young people.
researchers said: 'We found that the use of e-cigarettes before pregnancy significantly delayed the implantation of fertilized eggs into the womb, thereby delaying and reducing fertility.
also found that the use of e-cigarettes during pregnancy alters the long-term health and metabolism of female offspring, resulting in lifelong secondary effects on developing fetuses.
J Pathol: Why do certain cancers only affect young women? Doi:10.1002/path.5161 Of the many types of pancreatic cancer, only one affects the health of young women, so how is that possible? Although the pancreas is an organ that is rarely exposed to sex hormones, pancreatic cancer (called pancreatic mucus cysts) often has strange similarities to other mucus-like cancers, which affect the function of a woman's ovaries.
In a recent study published in the international journal The Journal of Pathology, scientists from the University of Geneva and other institutions analyzed large-scale genomic data and found that the tumor cells may have originated from embryonic stem cells, which migrate to the reproductive organs when they are undifferentiated, and that during the migration process, some cells are mistakenly present in other organs, creating a risk of tumours that may occur 30 years later.
by classifying mucus-like tumors, researchers may be able to develop individualized cancer therapies for the origin of tumors.
Mucus-like tumors of the ovaries and pancreas affect the health of young women between the ages of 30 and 40, forming larger cysts in patients, rarely accounting for only 3% of ovarian and pancreatic cancers, and can usually be surgically removed, if timely, cancerous In 15% of cases, however, the cyst breaks before surgery, allowing cancer cells to spread to the body's peritometrium, triggering metastasis cancer that is resistant to chemotherapy, in which case the patient's prognosis is often less than a year old.
/!-- ewebeditor:page--!--ewebeditor:page"--9-Plos Med: Childhood obesity increases teen death risk doi:1 Two studies published recently in the international journal PLoS Medicine and BMC Medicine show that childhood obesity is associated with an increased risk of premature death in adolescents and an increased risk of anxiety and depression.
paper, scientists from institutions such as Caroline College conducted a forward-looking study that compared the risk of mortality in youth among children with and without obesity, using data from 41,359 people.
researchers found 104 deaths (median 3.6 years) in 190,752 years of follow-up.
, 0.55 per cent of childhood obesity and 0.19 per cent of those in the comparison group died during follow-up.
more than a quarter of all deaths in the childhood obesity queue are recorded as the leading or leading cause of death.
10 eNeuro: Excessive drinking inhibits adolescent brain development doi:10.