Why is tobacco and alcohol addictive? Reveal the different neural loop mechanisms associated with smoking and drinking.

Why is tobacco and alcohol addictive? Recently, the international cooperation team led by Professor Feng Jianfeng, director of Fudan University's Institute of Brain-Like Brain Science and Technology, revealed the different neural loop mechanisms of smoking and drinking, and even a small amount of alcohol and alcohol has the opposite effect on the human brain: smokers are less sensitive to negative stimuli, while drinkers are more sensitive to positive stimuli, which may be an important cause of addiction to alcohol and alcohol.
recently, the study, entitled "The weakening of smoking brain connections and increased connectivity between the drinking brain", was published online in eLife, an authoritative journal in the field of biomedical sciences.
, the paper was selected as a special report on "eLife digest". The latest research results from feng Jianfeng's team at
show that the brain function connectivity of smokers shows a general weakening trend, while the brain function connectivity of drinkers shows an overall increase in the overall trend. Cheng Wei, a young researcher at Fudan University's Institute of Brain Intelligence, explained that brain function connection, that is, the synchronization of functional signals in different brain intervals, can be understood simply as synergy of brain intervals.

the various functions of the human brain require synergy between different brain regions.
" study found that the smoking group was less sensitive to brain punishment function, while the drinking group was more sensitive to brain reward function.
, " says Feng Jianfeng, which also explains the dependence of long-term smokers on nicotine and alcohol.
study also found that these brain connections to smoking and drinking were significantly associated with smoking, alcohol consumption, and impulsive behavior.
"It's worth noting that, through a data-driven approach, we can conclude in our study that a small amount of smoking and drinking can also exhibit abnormalities in brain connectivity that affect cognitive functions in the human brain."
" Feng Jianfeng said, this is another reminder to the public that the traditional understanding of the "small cigarettes and small wine does not hurt the body" view may lead to the wrong health habits.
it is understood that the study took two years.
the team combined the American Brain Connection Group Program and the European Adolescent Data Two Brain Imaging Database to model the brain network of nearly 2,000 subjects based on the static function magnetic resonance brain imaging data, and found neural loops closely related to smoking and drinking.
findings provide a theoretical basis for revealing the mechanisms of nicotine and alcohol's effect on the brain, and are important for the development of specific treatments for alcohol and tobacco addiction, a global public health problem.
Source: Xinhua.com.