-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
*Only for medical professionals to read for reference.
"Don't drink, just look down on me!" As the post-95s and post-00s enter the workplace, the online crusade against the wine table culture suddenly intensified
.
Alcohol is too unpleasant, dizzy and uncomfortable after being drunk, and it hurts the liver.
.
.
In fact, the harm of alcohol does not stop there
.
On July 13, The Lancet Oncology released a report on the global burden of cancer
.
The results of the report show that in 2020, there will be about 740,000 new cases of cancer worldwide that are causally related to alcohol consumption
.
When cases of gastric cancer and pancreatic cancer were included, the number of new cancer cases related to drinking increased to 810,000
.
Research screenshots Among these alcohol-related cancers, esophageal cancer, liver cancer, and breast cancer accounted for the largest proportion, with 190,000, 150,000 and 100,000 cases respectively
.
It is worth noting that the East Asian population, including China, has a higher risk of alcohol-related cancers than other regions
.
Compared with other carcinogenic factors, such as radiation, chemical exposure, genetics, etc.
, drinking occurs almost every day in the lives of Chinese people.
In any case, alcohol and cancer are not linked
.
But in fact, the causal relationship between alcohol and cancer has been proven by many studies
.
There are so many cancers related to drinking, I was shocked at first sight! The researchers counted the literature reports for 2020 and synthesized data from the International Agency for Research on Cancer (IARC) of the World Health Organization
.
Let’s take a look at the number of cancer cases that can be determined to be affected by alcohol consumption in the world in 2020: it turns out that drinking is associated with tongue cancer, oral cancer, esophageal cancer, colon cancer, rectal cancer, liver cancer, breast cancer, and laryngeal cancer.
Closely related
.
Table 1 The number of global alcohol attributable cancer cases, the population attributable proportion, and the age-standardized incidence rate of alcohol attributable cases by cancer type and gender in 2020.
Among these cancers, esophageal cancer, pharyngeal cancer, and lip cancer Oral cancer is the cancer most closely associated with drinking
.
However, the number of cases attributable to alcohol varies considerably among different sexes
.
For example, 39.
2% (95% UI 22.
7-55.
6) of esophageal cancer among men can be attributed to alcohol, while this figure is 14.
3% (95% UI 9.
0-23.
5) among women
.
Chinese people have the highest risk of causing cancer when drinking alcohol, but drinking more and more globally, people in East Asia and Eastern Europe have the highest risk of causing cancer when drinking alcohol
.
The article in the sub-Journal of The Lancet specifically mentioned China, which, along with Mongolia, Moldova, and Romania, is considered to be the area with the highest risk of alcohol-causing cancer
.
The map below shows the percentage of alcohol-related cancers in new cases of men (top) and women (bottom) around the world
.
The darker the color, the greater the ratio .
The proportion of global alcohol-attributable cancer cases in 2020 (male) The proportion of global alcohol-attributable cancer cases in 2020 (female) As can be seen from the figure, among the new male cancer cases in China, the proportion of alcohol-related cases , Has reached the darkest level in the world (≥6.
8%); among the new cancer cases of women in China, this proportion is not low (1.
3%~1.
8%)
.
However, in East Asia, alcohol consumption will increase in 2020
.
Simply put, there are more people who drink alcohol, and more people drink more.
.
What is the attributable percentage of the population of different alcohol intake, gender and region? You may be drinking too much! There is a common language: "Drinking for pleasure, a large drink hurts the body
.
" Family and friends gatherings, company annual meetings, wine tables, and a few drinks are inevitable
.
So, how many drinks are considered drinks? Is there a safe dose? This report divides the alcohol exposure of these 740,000 cases into 3 levels: moderate drinking: alcohol intake <20g (about 2 cups) per day; risk drinking: alcohol intake of 20~60g (about 2~ 6 cups per day; heavy drinking: alcohol intake> 60g (about 6 cups) per day
.
Everyone can check in to see if there is any excess of alcohol in your usual drinking.
Among the 740,000 cancer cases attributable to alcohol, 86.
1% of the cases of heavy drinking and risk drinking accounted for a total of 86.
1%, and only 13.
9% of the moderate drinking
.
Relatively speaking, the less alcohol you drink each day, the lower the risk of cancer
.
Although risky drinking and heavy drinking accounted for the majority of cancer cases, moderate drinking is also risky
.
Chinese people have a high risk of causing cancer when drinking alcohol.
Why? There is evidence that alcohol can cause cancer through a variety of biological pathways
.
Ethanol can be metabolized in the body to produce acetaldehyde, which may cause changes in DNA, protein, and lipids, leading to cancer
.
In the report released by The Lancet Oncology this time, we see obvious regional and gender differences
.
China even ranks among the areas with the highest risk of cancer from drinking, so why? Researchers believe that this is due to the higher frequency of acetaldehyde dehydrogenase mutant alleles (ALDH2*2) in East Asian populations
.
Aldehyde dehydrogenase (ALDH2) is one of the key enzymes in the ethanol metabolism pathway
.
People with ALDH2*2 mutant genes slow down the metabolism of acetaldehyde after drinking, and accumulate in the body, which can cause blushing, nausea, vomiting, sweating, heart palpitations and other adverse reactions, which is what we call "drinking on the face"
.
It is estimated that 28% to 45% of the East Asian population are carriers of ALDH2*2 gene mutations
.
People who "drink on the face" should generally drink less or no alcohol
.
However, the researchers found that in East Asia, these people still continue to drink
.
In addition, alcohol can also undergo oxidation in the body, change the homeostasis of hormone regulation (such as affecting the levels of estrogen and androgen in the body), alcohol itself can also become a solvent for other carcinogens.
.
.
all of these can increase the risk of cancer
.
The report also found that in areas with rapid economic development, as the proportion of female employment has increased, women’s drinking has also increased
.
And the more economically developed the region, the higher the burden of cancer caused by alcohol among women, and the more similar the ratio of men and women in the incidence of cancer caused by alcohol
.
Among them, breast cancer is a typical cancer related to alcohol intake
.
In 2020, the number of new female breast cancer cases in China will reach 410,000, accounting for 19.
9% of new female cancer cases
.
Wine table culture is the dregs of the workplace.
"The world is suffering for a long time
.
" It is not difficult to understand the rising consumption of alcohol in China
.
The "hidden rules" of drinking and talking about business and drinking and making friends are not uncommon in the workplace
.
When I searched for the wine table culture in the last one, I found 20 or 30 rules
.
Zhihu screenshots Previously, a new employee of a bank was insulted by the leader for refusing a toast to the president at the company's annual meeting, and was subsequently chased by colleagues to the elevator entrance
.
Although this phenomenon is a typical case, the wine table culture is everywhere
.
Social drinking, is considered an "alliance of interests and loyalty to authority"
.
Whether it is a person who "drinks on the face", or a woman in the workplace, or anyone who is unwilling to drink at the wine table, when others persuade you to drink, do you drink or not? "Alcohol is a fluid emotional lubricant.
If you don't drink it, you despise me.
If I drink it, you can take care of it.
.
.
" "Allergies? Allergies means that you can exercise by drinking less and drinking more
.
" "Are you fatty liver? I still have gallstones, clink a glass, and we are brothers who care about each other
.
"After three rounds of drinking, no matter how legitimate the reason is, it becomes a joke
.
Now, the global cancer data for 2020 has told us that drinking alcohol causes cancer, and the number of cancer cases in China due to drinking alcohol is increasing year by year
.
Drinking is useless, and the wine table culture is not traditional and should not be passed on
.
When will it end? We will wait and see
.
References: [1]Harriet Rumgay, Kevin Shield et al.
Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study.
Lancet Oncol.
2021 July.
https://doi.
org/10.
1016/S1470-2045 (21)00279-5[2]https://
"Don't drink, just look down on me!" As the post-95s and post-00s enter the workplace, the online crusade against the wine table culture suddenly intensified
.
Alcohol is too unpleasant, dizzy and uncomfortable after being drunk, and it hurts the liver.
.
.
In fact, the harm of alcohol does not stop there
.
On July 13, The Lancet Oncology released a report on the global burden of cancer
.
The results of the report show that in 2020, there will be about 740,000 new cases of cancer worldwide that are causally related to alcohol consumption
.
When cases of gastric cancer and pancreatic cancer were included, the number of new cancer cases related to drinking increased to 810,000
.
Research screenshots Among these alcohol-related cancers, esophageal cancer, liver cancer, and breast cancer accounted for the largest proportion, with 190,000, 150,000 and 100,000 cases respectively
.
It is worth noting that the East Asian population, including China, has a higher risk of alcohol-related cancers than other regions
.
Compared with other carcinogenic factors, such as radiation, chemical exposure, genetics, etc.
, drinking occurs almost every day in the lives of Chinese people.
In any case, alcohol and cancer are not linked
.
But in fact, the causal relationship between alcohol and cancer has been proven by many studies
.
There are so many cancers related to drinking, I was shocked at first sight! The researchers counted the literature reports for 2020 and synthesized data from the International Agency for Research on Cancer (IARC) of the World Health Organization
.
Let’s take a look at the number of cancer cases that can be determined to be affected by alcohol consumption in the world in 2020: it turns out that drinking is associated with tongue cancer, oral cancer, esophageal cancer, colon cancer, rectal cancer, liver cancer, breast cancer, and laryngeal cancer.
Closely related
.
Table 1 The number of global alcohol attributable cancer cases, the population attributable proportion, and the age-standardized incidence rate of alcohol attributable cases by cancer type and gender in 2020.
Among these cancers, esophageal cancer, pharyngeal cancer, and lip cancer Oral cancer is the cancer most closely associated with drinking
.
However, the number of cases attributable to alcohol varies considerably among different sexes
.
For example, 39.
2% (95% UI 22.
7-55.
6) of esophageal cancer among men can be attributed to alcohol, while this figure is 14.
3% (95% UI 9.
0-23.
5) among women
.
Chinese people have the highest risk of causing cancer when drinking alcohol, but drinking more and more globally, people in East Asia and Eastern Europe have the highest risk of causing cancer when drinking alcohol
.
The article in the sub-Journal of The Lancet specifically mentioned China, which, along with Mongolia, Moldova, and Romania, is considered to be the area with the highest risk of alcohol-causing cancer
.
The map below shows the percentage of alcohol-related cancers in new cases of men (top) and women (bottom) around the world
.
The darker the color, the greater the ratio .
The proportion of global alcohol-attributable cancer cases in 2020 (male) The proportion of global alcohol-attributable cancer cases in 2020 (female) As can be seen from the figure, among the new male cancer cases in China, the proportion of alcohol-related cases , Has reached the darkest level in the world (≥6.
8%); among the new cancer cases of women in China, this proportion is not low (1.
3%~1.
8%)
.
However, in East Asia, alcohol consumption will increase in 2020
.
Simply put, there are more people who drink alcohol, and more people drink more.
.
What is the attributable percentage of the population of different alcohol intake, gender and region? You may be drinking too much! There is a common language: "Drinking for pleasure, a large drink hurts the body
.
" Family and friends gatherings, company annual meetings, wine tables, and a few drinks are inevitable
.
So, how many drinks are considered drinks? Is there a safe dose? This report divides the alcohol exposure of these 740,000 cases into 3 levels: moderate drinking: alcohol intake <20g (about 2 cups) per day; risk drinking: alcohol intake of 20~60g (about 2~ 6 cups per day; heavy drinking: alcohol intake> 60g (about 6 cups) per day
.
Everyone can check in to see if there is any excess of alcohol in your usual drinking.
Among the 740,000 cancer cases attributable to alcohol, 86.
1% of the cases of heavy drinking and risk drinking accounted for a total of 86.
1%, and only 13.
9% of the moderate drinking
.
Relatively speaking, the less alcohol you drink each day, the lower the risk of cancer
.
Although risky drinking and heavy drinking accounted for the majority of cancer cases, moderate drinking is also risky
.
Chinese people have a high risk of causing cancer when drinking alcohol.
Why? There is evidence that alcohol can cause cancer through a variety of biological pathways
.
Ethanol can be metabolized in the body to produce acetaldehyde, which may cause changes in DNA, protein, and lipids, leading to cancer
.
In the report released by The Lancet Oncology this time, we see obvious regional and gender differences
.
China even ranks among the areas with the highest risk of cancer from drinking, so why? Researchers believe that this is due to the higher frequency of acetaldehyde dehydrogenase mutant alleles (ALDH2*2) in East Asian populations
.
Aldehyde dehydrogenase (ALDH2) is one of the key enzymes in the ethanol metabolism pathway
.
People with ALDH2*2 mutant genes slow down the metabolism of acetaldehyde after drinking, and accumulate in the body, which can cause blushing, nausea, vomiting, sweating, heart palpitations and other adverse reactions, which is what we call "drinking on the face"
.
It is estimated that 28% to 45% of the East Asian population are carriers of ALDH2*2 gene mutations
.
People who "drink on the face" should generally drink less or no alcohol
.
However, the researchers found that in East Asia, these people still continue to drink
.
In addition, alcohol can also undergo oxidation in the body, change the homeostasis of hormone regulation (such as affecting the levels of estrogen and androgen in the body), alcohol itself can also become a solvent for other carcinogens.
.
.
all of these can increase the risk of cancer
.
The report also found that in areas with rapid economic development, as the proportion of female employment has increased, women’s drinking has also increased
.
And the more economically developed the region, the higher the burden of cancer caused by alcohol among women, and the more similar the ratio of men and women in the incidence of cancer caused by alcohol
.
Among them, breast cancer is a typical cancer related to alcohol intake
.
In 2020, the number of new female breast cancer cases in China will reach 410,000, accounting for 19.
9% of new female cancer cases
.
Wine table culture is the dregs of the workplace.
"The world is suffering for a long time
.
" It is not difficult to understand the rising consumption of alcohol in China
.
The "hidden rules" of drinking and talking about business and drinking and making friends are not uncommon in the workplace
.
When I searched for the wine table culture in the last one, I found 20 or 30 rules
.
Zhihu screenshots Previously, a new employee of a bank was insulted by the leader for refusing a toast to the president at the company's annual meeting, and was subsequently chased by colleagues to the elevator entrance
.
Although this phenomenon is a typical case, the wine table culture is everywhere
.
Social drinking, is considered an "alliance of interests and loyalty to authority"
.
Whether it is a person who "drinks on the face", or a woman in the workplace, or anyone who is unwilling to drink at the wine table, when others persuade you to drink, do you drink or not? "Alcohol is a fluid emotional lubricant.
If you don't drink it, you despise me.
If I drink it, you can take care of it.
.
.
" "Allergies? Allergies means that you can exercise by drinking less and drinking more
.
" "Are you fatty liver? I still have gallstones, clink a glass, and we are brothers who care about each other
.
"After three rounds of drinking, no matter how legitimate the reason is, it becomes a joke
.
Now, the global cancer data for 2020 has told us that drinking alcohol causes cancer, and the number of cancer cases in China due to drinking alcohol is increasing year by year
.
Drinking is useless, and the wine table culture is not traditional and should not be passed on
.
When will it end? We will wait and see
.
References: [1]Harriet Rumgay, Kevin Shield et al.
Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study.
Lancet Oncol.
2021 July.
https://doi.
org/10.
1016/S1470-2045 (21)00279-5[2]https://
