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    Home > Active Ingredient News > Drugs Articles > With the rise of "AI" pharmaceuticals, can pharmaceutical companies achieve "overtaking in curves"?

    With the rise of "AI" pharmaceuticals, can pharmaceutical companies achieve "overtaking in curves"?

    • Last Update: 2022-10-12
    • Source: Internet
    • Author: User
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    In September 2022, Pfizer announced the extension of its partnership with CytoReason to use CytoReason's AI technology for Pfizer's drug development program


    New drug research and development has the outstanding characteristics of "three highs and one long", that is, high technology, high investment, high risk and long cycle


    Comparison of the advantages of AI and traditional drug development

    Comparison of the advantages of AI and traditional drug development

    AI pharmacy mainly refers to the application of artificial intelligence technologies such as natural language processing, machine learning and big data to all aspects of the pharmaceutical field to improve and optimize the efficiency and quality of new drug research and development, and reduce the probability of clinical failure and research and development costs


    The disease direction that pharmaceutical companies focus on AI cooperation

    The disease direction that pharmaceutical companies focus on AI cooperation

    (As of November 2020)

    (As of November 2020)

    Latest research advances

    Latest research advances

    1.


    Source: Gloria Ing

    2.


    Financing in the AI pharmaceutical sector in 2021

    Financing in the AI pharmaceutical sector in 2021

    3.


    4.


    Source: BCC and Grand View Research

    Introduction of key enterprises and technologies

    Introduction of key enterprises and technologies

    1、Exscientia

    1、Exscientia

    Founded in the United States in 2012, Exscientia applied AI and big data processing to accelerate drug discovery and development, and was the first company


    2.


    2.


    3、CytoReason

    3、CytoReason

    CytoReason is an innovative Israeli medical technology company focused on using its AI technology platform to develop therapies for a wide range of diseases, covering areas such as


    4.


    4.


    5.


    5.


    6.


    6.
    Deep Zhiyao

    Deepin Zhiyao (DIP) is a national high-tech enterprise
    that uses artificial intelligence technology to empower the whole process of new drug research and development.
    The company is committed to building an end-to-end AI-driven new drug research and development platform to empower and accelerate the comprehensive and intelligent digitalization
    of the pharmaceutical R&D department.
    Through the construction of a knowledge graph (Di-GraPhMed), the drug reuse platform and the artificial intelligence small molecule drug discovery platform (Di-DrugGOES) are built to realize the whole process
    of intelligent drug reuse based on multi-dimensional efficient collaboration such as data mining, structure-activity relationship, signal pathway and expert verification 。 The company deeply combines Di-GraPhMed and Di-DrugGOES, predicts new drug targets and indications based on massive literature, database data sets and compound structures, and quickly circumvents existing patents in Di-DrugGOES to achieve drug relocation; Using LINCS and using the relevant genome datasets in cell lines, the Di-PASS algorithm platform was used to analyze gene differential expression, signaling pathway (KEGG) and human co-expression gene module (COXPERSdb), the pathway activity was evaluated, and the pathway and similarity scores were obtained based on the drugs that have been marketed, and the potential new indications of the positioning compound were analyzed
    .
    At present, the company has served more than 20 pharmaceutical listed companies and research institutions around the
    world.

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