Working principle of refrigeration dryer

Working principle of freeze dryer working principle of freeze dryer is a kind of drying technology based on the principle of sublimation It is a process that the dried water containing substances are quickly frozen into solid state at low temperature in advance, and then the frozen water molecules are directly sublimed into water vapor to escape to remove the water and preserve the substances in proper vacuum environment The product obtained by freeze-drying is called lyophilizer The process is called lyophilization In order to ensure the biological activity and quality of the sample, it is necessary to pre freeze the sample first, and then put it on the shelf of the freeze-drying warehouse after pre freezing in the refrigerator or freeze-drying machine to carry out the main drying process of the sample At this time, the moisture in the sample sublimates directly to steam under the action of low temperature and high vacuum of the freeze dryer, which is supplemented by the low temperature cold trap and vacuum pump After several dozens of hours of drying, most of the water in the sample is sublimated, and the sample is completely preserved The sublimated gas condenses Huawei ice in the cold well Due to the pressure relationship, there is continuous gas sublimation and then condenses into ice in the cold well When the ice sublimates, it needs to absorb heat, which causes the temperature of the sample to drop and slows down the sublimation speed In order to increase the sublimation speed, To shorten the drying time, it is necessary to heat the product properly In order to ensure a higher purity of the sample, the sample can be heated and lyophilized at this time, which can also be called post drying process When the sample temperature reaches room temperature, the whole lyophilization process can be completed The material is always in low temperature (frozen state) before drying, and ice crystals are evenly distributed in the material The sublimation process will not be condensed due to dehydration, avoiding the side effects such as froth and oxidation caused by steam ② The volume of the dry material is the same as that of the sponge, which is easy to dissolve in water and return to the form before freeze-drying ③ The common drying principle is to use heating methods, but these drying methods are carried out at a temperature above 0 ℃ or higher The dried products have great changes in physical and chemical shape In the freeze-drying process, the growth of microorganisms and the role of enzymes can not be carried out Zui can largely prevent the original biological and chemical properties of dried substances from denaturing, with good stability and easy to long-term preservation ④ The products are dried, desorbed, dehydrated and pressed in aseptic condition in the freeze-drying chamber ⑤ It can remove 95% ~ 99% water in the substance ⑥ It is especially suitable for the dry storage of heat sensitive substances, such as vaccines, strains, viruses, blood products, etc ⑦ The main components of the lyophilizer have Zui optimal structure layout, which is conducive to the operation of transportation, installation and production; is conducive to cleaning and maintenance, and conforms to GMP requirements Features of Ningbo Shuangjia freeze dryer: ★ automatic control system of freeze dryer programmable freeze dryer, all freeze-drying processes, from freeze-drying to defrosting, are controlled by program ★ the partition heating system controls the temperature through the circulating heat generated by heating the partition, so the temperature uniformity is more accurate, and the freeze-drying speed is improved at the same time ★ the freeze-drying room of the sample pre freezing system has a freezing system, which can pre freeze the sample before freeze-drying ★ the pure nitrogen back filling system (mostly used for biological products) is * to save the sample The back filling system can be used to fill the vacuum bin with sterile air or nitrogen to protect the sample from pollution ★ in order to preserve the sample after freeze-drying, the safety gland system is used in vacuum state to achieve the safety and sealing effect ★ anti back injection device of anti vacuum pump oil back injection system, to protect the sample, prevent the vacuum pump oil from flowing back to the system and polluting the sample ★ secondary delay start system of compressor: protect the compressor and extend its service life ★ remote computer control is optional ★ optional with USB online function, export curve data to USB disk ★ bottle hanging function: optional with 4 freeze-drying bottles or 24 split bottles, observe sample drying at any time, without shutting down Because of its characteristics, freeze-drying technology is widely used in chemical industry, biological products and other fields SJIA company has ten years of experience in the refrigeration industry, and the developed freeze dryer is in the leading position in the refrigeration industry in China.