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Innovent's Class 1 new drug IBI112 starts Phase I clinical trial

 Last Update: 2020-09-04
 Source: Internet
 Author: User

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The main purpose of the study was to evaluate the safety and tolerance of Chinese health subjects after a single dose of off-the-cortective injection or intravenous injection of IBI112.
secondary purpose was to evaluate the characteristics and immunogenicity of post-drug pharmacological dynamics (PK) of IBI112 in a single dose of subderfic injection or intravenous giving to healthy subjects in China.
purpose of the study was to evaluate the post-IBI112 pharmacodynamic (PD) characteristics of single-dose subderfect injections or intravenous giving to healthy subjects in China.
IBI112 is an IL-23 monoantigen, IL-23 is a new type of isogenic cytokine consisting of IL-12/IL-23p40 and specific IL-23p19 sub-base.
-23 play an important role in autoimmune diseases, rheumatoid arthritis and inflammatory bowel diseases and infections.
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