-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
<>.
Bacteria have developed many sophisticated defense systems in their long-term game with bacteriophages, including the CRISPR system
The Yang Hui research group of the Center of Excellence for Brain Intelligence of the Chinese Academy of Sciences has demonstrated that the bacterial retron system can be reversed transcribed in mammalian cells by expressing four retron systems (Ec48 , Ec73 , Ec86 and Ec107) that have been reported to have functions in mammalian cells.
FIG 2 Retron Editing work and its schematic DNA base editor, Prime Editing Comparison
Compared with the more commonly used DNA single-base editing and Prime editing , Retron editing that relies on HDR mechanism is relatively less restricted by the position of PAM ; moreover, Retron editing system does not need to provide additional foreign donor template DNA .
The research was completed by Dr.
