echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > Young people got Parkinson's disease after contracting the new crown!

    Young people got Parkinson's disease after contracting the new crown!

    • Last Update: 2021-12-28
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    The scary thing about the new coronavirus is that it not only causes respiratory symptoms, but also affects other tissues and organs


    In the journal ACS Chemical Neuroscience under the American Chemical Society, researchers found that the N protein of the new coronavirus can interact with α-synuclein to accelerate the formation of amyloid deposits


    Cases of neurodegenerative disease caused by viral infection are not uncommon


    For neurodegenerative diseases such as Parkinson's disease, abnormal accumulation of certain proteins is a typical pathological feature


    Based on the symptoms of Parkinson's disease in some young people after contracting the new crown, the researchers decided to explore the relationship between the two diseases


    In the absence of the new coronavirus, the researchers found that it takes more than 240 hours for α-synuclein to accumulate to form fibrils


    What's interesting is that when they added the N protein from the new coronavirus, the speed of deposition formation was greatly accelerated-it only takes less than 24 hours for α-synuclein to accumulate!

    ▲The effect of new crown S protein (left picture) and N protein (right picture) on the deposition rate of α-synuclein


    Further research found that the N protein and α-synuclein of the new coronavirus can be directly combined with each other through different charges! In the model, each N protein can bind at least 3-4 different α-synuclein


    In order to confirm the results observed in the test tube, the researchers used a Parkinson's disease cell model for analysis


    What is even more exaggerated is that after the simultaneous injection of N protein, the distribution of many α-synuclein proteins has changed, and the structure has also been lengthened, which makes people doubt whether this is amyloid deposition (not yet confirmed)


    ▲This study found that the new crown N protein can bind to the typical pathological protein of Parkinson’s disease α-synuclein (picture source: reference [2]; Adapted from ACS Chemical Neuroscience 2021, DOI: 10.


    The authors pointed out that a major symptom of the new crown we know is that people lose their sense of smell and taste, and the loss of smell and taste is precisely the early symptom of Parkinson's disease


    Reference materials:

    [1] Slav A.


    [2] SARS-CoV-2 protein interacts with Parkinson's protein, promotes amyloid formation, Retrieved December 14, 2021, from https://

    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.