Zhang Haiyuan research group of Changchun Institute of chemical engineering, Chinese Academy of Sciences has made a series of progress in the study of biological response under the control of photoelectric properties of nano materials

The signal response of biomaterials based on optoelectronic properties is becoming a hot topic in the field of nanobiology To clarify the energy level structure, interface electronic transmission and the formation rule of light controlled species of nano materials is helpful to control the biological behavior and behavior under the nano biological interface, so as to design and prepare intelligent, safe and efficient nano system for the diagnosis and treatment of cancer and other major diseases Zhang Haiyuan research group of Changchun Institute of Applied Chemistry, Chinese Academy of Sciences recently reported a new type of bismuth gold sulfide nano heterogeneous material, which is used in the minimally invasive treatment of tumor Based on the deep level defect theory, the team first revealed the photothermal nature of narrow band Bismuth Sulfide Nanomaterials different from the traditional materials The new bismuth gold nanoheterostructure constructed by the energy level embedding principle can significantly improve the density of deep level defects, thus increasing the near-infrared photothermal conversion efficiency of Bismuth Sulfide Nanomaterials from 33.6% to 51.1% Furthermore, the in vitro and in vivo biological signal detection of spatiotemporal diversity verifies its safety and efficiency in tumor photothermal ablation The research results were published as VIP articles in recent angew Chem Int ed 2018, 57, 246, and obtained the key push and comment from the special contributors on Wiley's official website (http://newsroom.wiley.com/press-release/angewandte-chemie-international-edition/tumors-heat-new-method-more-effective-photo the) Figure: deep level defects (BIS and vs) in narrow band Bi 2S 3-au nanomaterials can promote non radiation recombination of photogenerated electrons and holes, produce high-density phonons, trigger photothermal properties, stimulate the expression of heat shock proteins, induce apoptosis, and lead to thermal stress injury of tumors Based on the optoelectronic properties of nanomaterials, the research group has widely expanded its application in biological systems and achieved a series of research results, including the use of dislocation energy levels to construct nanomaterials for photodynamic therapy of skin cancer (small 2017, 13, 1603935), the use of crystal heterogeneity to construct new antibacterial nanomaterials (ACS appl Mater Interfaces 2017, 9 , 5907), to clarify the potential impact of the atomic arrangement specificity on the biosafety of nanomaterials (ACS Nano 2016, 10, 6062) and to measure the toxic initiation intensity of nanomaterials by band bending level (J am Chem SOC 2014, 136, 6406) The research was supported by the "Hundred Talents Program" of the Chinese Academy of Sciences and the National Natural Science Foundation of China Paper link: http://onlinelibrary.wiley.com/doi/10.1002/anie.201710399/abstract introduction to researcher Zhang Haiyuan: http://yjsb.cic.jl.cn/daoshi_read PHP? Brown = 430 researcher Zhang Haiyuan