Zhu Chengzhou, Professor of central China Normal University: single atom iron enhanced Electrochemiluminescence

Lead electrochemiluminescence (ECL) technology is widely used in biological analysis, clinical diagnosis, drug analysis and environmental detection because of its simple and high efficiency, low background interference and high sensitivity Among them, there are many studies on Luminol-H 2O 2-based electrochemiluminescence system However, the stability of H 2O 2 is poor and it is easy to decompose at room temperature, which brings great interference to quantitative analysis Compared with H 2O 2, dissolved O 2 in the system, as an endogenous CO reactant, has the advantages of high stability and low toxicity, and has gradually become a new research hotspot How to improve the efficiency of conversion of CO reactant O 2 to reactive oxygen species, and ultimately achieve the enhancement of luminol's electrochemiluminescence intensity, is a challenging task Recently, Professor Zhu Chengzhou's research group of central China Normal University has innovatively adopted monoatomic catalyst as a high-efficiency cocatalyst, and made a new breakthrough in this research field (a gew Chem Int ed 2019, DOI: 10.1002/anie.201914643) Prof Zhu Chengzhou, professor and doctoral supervisor, School of chemistry, central China Normal University Selected youth project of "overseas high level talent introduction plan" of the Central Organization Department, Humboldt scholar of Germany, Editorial Committee of International Journal "analytica chimica Acta" and "current catalysis", and young Editorial Committee of Journal of physical chemistry In January 2013, he graduated from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, with a doctorate in science, and studied with Dong Shaojun, academician of the Third World Academy of Sciences In the same year, he won Humboldt scholarship and worked with Professor Alexander eychm ü ller at Dresden University of technology in Germany for postdoctoral research From June 2014 to April 2018, he worked as an assistant research professor at Washington State University in cooperation with Professor Yuehe Lin The main research direction is catalysis and bioanalysis of functional nanomaterials So far, he has published more than 170 academic papers in Chem Rev., chem SOC Rev., adv mater., angelw Chem Int ed., ACS Nano, adv energy mater., nano energy, ACS energy lett., chem Mater., small and anal Chem And other internationally renowned academic journals, with a total citation of nearly 11500 times (Google Scholar), and an H-index of 56 Front research results: compared with the traditional Luminol-H 2O 2 system, the luminol-o 2 system shows enhanced stability, but its luminous efficiency is much weaker Therefore, luminol-o2 needs more efficient cocatalyst to realize the conversion of oxygen to active oxygen Although there have been some reports of high efficiency cocatalysts based on Au Ag Pt and CeO 2 / SNS 2, their performance still needs to be further improved In addition, the structure of these reported catalytic materials is more complex, so it is difficult to further explore the mechanism of electrochemiluminescence Single atom catalysts have great potential in the field of electrocatalysis due to their maximum atomic utilization and high catalytic efficiency It is worth noting that the active site structure of monatomic catalyst is clear, which is convenient for the study of related mechanism Professor Zhu Chengzhou's research group has been engaged in the development and design of monatomic materials for a long time, and has been successfully applied in the field of electrocatalysis and nano enzyme (angel Chem Int ed 2017, 56, 13944-13960; angel Chem Int ed doi: 10.1002/anie.201905645; adv energy mater 2018, 8, 1801956; small 2019, 15, 1903108; s mall 2017, 13, 1603407; S mall
2018 , 14 , 1703118; Small
2019 , 15 , 1900307; Anal Chem   2019 ,  91 , 11994-11999 ） 。 Based on the research in the above fields, the research team boldly envisages whether the mono atom catalyst can be used as a cocatalyst to promote the electrochemiluminescence of oxygen and luminol It is found that the unique electronic structure and catalytic activity of fe-n-c sacs can effectively promote the reaction of luminol anion radicals with oxygen to produce a large number of active oxygen substances, thus significantly amplifying luminol luminescence signal Based on the above phenomena, the research group has successfully designed a luminol-o 2 electrochemiluminescence sensor for oxidation resistance test, which shows a good linear relationship in the concentration range of 0.8 μ m-1.0 mm Trolox Therefore, the development of the single atom catalyst will provide a new way to further study luminol electrochemiluminescence system First of all, the prepared monoatomic iron catalyst has been characterized in a series (Fig 1) The results show that the isolated iron atoms are evenly distributed on the carbon carrier The results of ICP test show that the loading amount of monatomic iron is 1.3% Fig 1 Fe-n-c sacs (a) and (b) low power tems, (c) ac-haadf-stem, (d) - (g) HAADF-STEM mapping (source: a gew Chem Int ed.) The results of XANES and EXAFS show that there is no Fe bond in fe-n-c catalyst, and iron protons are mainly coordinated with four nitrogen atoms Fig 2 Spectra of fe-n-c sacs (a) XANES and (b) EXAFS (source: a gew Chem Int ed.) Then, the author found that fe-n-c sacs catalyst can significantly enhance luminol luminescent intensity and has good stability by comparing nitrogen doped carbon materials with Fe3O4 nanomaterials Fig 3 (a) comparison of bare glassy carbon electrode, CN, Fe3O4 nanoparticles and fe-n-csas ECL, (b) fe-n-c sacs ECL stability test (source: a gew Chem Int ed.) finally, under the best conditions, a fe-n-c sacs-luminol e CL sensor for the determination of antioxidant capacity was designed and developed Detection of antioxidants in different beverages Fig 4 (a) mechanism diagram of fe-n-c sacs luminol e Cl, (b) and (c) linear relationship between luminol intensity and Trolox concentration, (d) fe-n-c sacs-luminol e CL detection of antioxidants in beverages (source: a gew Chem Int ed.) In conclusion, the author found that the use of monoatomic iron catalyst as a cocatalyst can promote the production of active oxygen substances, significantly amplify luminol luminescence signal, and build a new luminol -The dissolved oxygen sensing platform also provides a new way to study the enhancement mechanism of luminol electrochemiluminescence at the single atom scale This achievement was recently published in angel Chem Int ed (DOI: 10.1002 / anie 201914643) The authors of this paper are: Wenling g u, ා HENGJIA Wang, ා Lei Jian, Yu Wu, Yuxin Chen, Liuyong Hu, * Jingming Gong, Dan Du, Chengzhou Zhu * Nowadays, people and scientific research have been paid more and more attention in the economic life China has ushered in the "node of science and technology explosion" Behind the progress of science and technology is the work of countless scientists In the field of chemistry, in the context of the pursuit of innovation driven, international cooperation has been strengthened, the influence of Returned Scholars in the field of R & D has become increasingly prominent, and many excellent research groups have emerged in China For this reason, CBG information adopts the 1 + X reporting mechanism CBG information website, chembeangoapp, chembeango official micro blog, CBG information wechat subscription number and other platforms jointly launch the column of "people and scientific research", approach the representative research groups in China, pay attention to their research, listen to their stories, record their demeanor, and explore their scientific research spirit.