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Lin Aifu's research group of the Chinese Academy of Biological Sciences published a paper in Nature Metabolism to reveal RNA-mediated organelles...
Time of Update: 2022-09-27
Figure 1 Cholesterol regulates SNHG6-FAF2-mTOR signaling complex assembly in the organelle interaction regionFurther, the authors used a cholesterol-induced naflD-HCC mouse model to confirm the regulatory role of SNHG6 in the dynamic evolution of tumors, and found that overexpression of SNHG6 in mouse livers will promote the activation of the cholesterol-induced mTORC1 signaling pathway and accelerate the malignant lesion process from non-alcoholic fatty liver to liver cancer in mouse livers.
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Professor Xia Ningshao's team has revealed a new mechanism of antibody cocktail therapy
Time of Update: 2022-09-27
Antibody therapy is an important means of prevention and treatment of infectious diseases, antibody cocktail therapy is considered to be a more effective treatment than monotherapy, usually has the ad
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The team of Aiwu Dong, Jianhua Gan, and Jianxun Huang collaborated to reveal the molecular mechanism by which different MYB and bHLH transcription factors in plants select partners to form complexes
Time of Update: 2022-09-27
Aiwu Dong, Jianhua Gan, and Jianxun Huang teamed up to reveal different MYB and bHLH transcription factors in plantsMolecular mechanisms by which select partners form complexesOn August 22, 2022, aiwu Dong, Jianhua Gan and Jianxun Huang of the School of Life Sciences of Fudan University collaborated to publish a research paper entitled "Structural insights into partner selection for MYB and bHLH transcription factor complexes" online in nature plants journal.
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The role of DNA methylation in regulating the development and maturation of fruits
Time of Update: 2022-09-27
Transcriptional levels of ripening-related genes in tomato fruit were studied by transcriptome sequencing, and the expression of multiple mature-related genes such as PE1, PG2, and LOXB in the CR-08 mutant line was upregulated.
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UBA6 Crystal Structure Publication reveals which mutations in UBA6 selectively shut down ubiquitination and FAT10 function
Time of Update: 2022-09-21
A key to the study is to identify UBA6 mutations that can cause UBA6 selective FAT10 deficiency or ubiquitin deficiency.
A key to the study is to identify UBA6 mutations that can cause UBA6 selective FAT10 deficiency or ubiquitin deficiency.
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Hailin Peng's research group and collaborators in the School of Chemistry and Molecular Engineering reported on the infrared detection of a new two-dimensional semiconductor Bi2O2Se heterojunction
Time of Update: 2022-09-21
2D semiconductor Bi2O2Se/BP van Der Waals heterojunction infrared photodetector with quantum efficiency and polarization characteristics As the "clairvoyance" for people to observe nature, infrared light detectors play an important role in infrared night vision, security reconnaissance and military remote sensing.
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A new data analysis method identifies splicing variants associated with disease
Time of Update: 2022-09-21
Source: Department of Genomic Function and Diversity, TMDUResearchers from Tokyo Medical and Dental University (TMDU) have found that integrating and selectively analyzing spliced variant data can help identify genetic variants associated with complex human diseases In the era of big data, access to a lot of information is the easiest part; Knowing how to take advantage of it is another matter entirely.
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Nature's mechanism for extending lifespan through the self-help "recycling system" of cells
Time of Update: 2022-09-21
"Lysosomal damage is a marker of aging and many diseases, particularly neurodegenerative diseases such as Alzheimer's," said lead author Jay Xiaojun Tan, Ph. D.
Nature, 2022 "Lysosomal damage is a marker of aging and many diseases, particularly neurodegenerative diseases such as Alzheimer's," said lead author Jay Xiaojun Tan, Ph. D.
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He Yan's team from the Department of Laboratory Medicine of Zhujiang Hospital found that there is an age-dependent correlation between intestinal microbiota aging and metabolic diseases
Time of Update: 2022-09-21
A number of population studies have found that the intestinal flora is closely related to age, there is a trajectory of change from youth to aging, and a number of animal experiments have also found that transplanting the intestinal flora of elderly animals will have an adverse impact on host metabolism, immunity, nerves, etc.
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【Research Dynamics】Professor Guo Anyuan's team at the School of Life Sciences of Huazhong University of Science and Technology identified RNA features in a single extracellular vesicle for the first time
Time of Update: 2022-09-21
Figure 1 Article informationThis study proposes a high-throughput sequencing method for EVs based on the 10x Genomics platform, which explores the characteristics of the EVs transcriptome at the single EV level.
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MIT conducted an in-depth study of duplicate protein sequences
Time of Update: 2022-09-21
They found that while LCRs will vary in different proteins and species, they often have a similar role — helping proteins join larger combinations, such as nucleoli, a type of organelle found in almost all human cells.
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Textbooks have been updated again, with different effects of elevated carbon dioxide concentrations on plant growth
Time of Update: 2022-09-21
"We found that the increase in phytic acid levels in plants needs to be tightly controlled in order for plants to grow in a high carbon dioxide environment.
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Stone Age surgery: the earliest evidence of amputation found
Time of Update: 2022-09-21
" The findings, published in the journal Nature, describe the skeletal remains of a young adult found in a cave in Borneo, East Kalimantan, where at least 31,000 years ago — whose left calf and part of his left foot were amputated, possibly in childhood, and the patient survived the operation, surviving at least 6 to 9 years.
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Luo Donggen's team in the School of Life Sciences has discovered a new type of electrical signal that maintains a circadian rhythm
Time of Update: 2022-09-21
On September 2, 2022, a team of researchers from the School of Life Sciences of Peking University, the McGovern Brain Institute, the Center for Quantitative Biology, and the Joint Center for Life Scie
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Guangxi key R&D plan project "Research and Demonstration of Multi-interface Runoff Storage and Intelligent Irrigation Technology in Fruit Forest Slopes in DashiShan District" was held at the project launch and implementation plan demonstration meeting
Time of Update: 2022-09-21
On September 9, the Institute of Subtropical Agroecology of the Chinese Academy of Sciences organized and held the project kick-off meeting and implementation plan demonstration meeting of the Guangx
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Studies have shown that previous vaccinia virus (VACV)-based vaccines can effectively prevent the novel monkeypox virus MPXV-2022
Time of Update: 2022-09-21
A few weeks after the new strain appeared, Professor Matthew MCKAY, a researcher at the University of Melbourne's Future Research Centre, and Professor Ahmed Abdul QUADEER, an assistant researcher at the Hong Kong University of Science and Technology (HKUST), co-led a genomic study of MXV-2022 to determine whether genetic mutations observed in MXXV-2022 might affect the VACV vaccine-induced immune response to monkeypox.
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Wu Xiaosong's research group and collaborators in the School of Physics discovered heterodimensional superlattice structures and intra-plane anomalous Hall effects
Time of Update: 2022-09-21
Fig. 1 VS2-VS heterodimensional superlattice structureThe novel intra-surface Hall effect discovered by the experiment stems from a special form of spin orbit coupling in this material.
Fig. 1 VS2-VS heterodimensional superlattice structureThe novel intra-surface Hall effect discovered by the experiment stems from a special form of spin orbit coupling in this material.
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Nature Medicine genetics have a significant impact on healthy longevity
Time of Update: 2022-09-21
63 DALYs. The effect of some common variants on population levels is comparable to modifiable risk factors such as high sodium intake and low physical activity.
63 DALYs. The effect of some common variants on population levels is comparable to modifiable risk factors such as high sodium intake and low physical activity.
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Li Dan's research group and collaborators at Shanghai Jiaotong University explained the molecular mechanism of Hsp27 inhibiting pathological aggregation and toxicity of pTau in Alzheimer's disease
Time of Update: 2022-09-21
Alzheimer's disease (AD) as the most common neurodegenerative disease, the current global confirmed patients have exceeded 50 million, there is no specific drug, which seriously affects human life and
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The He Yawen team of Shanghai Jiaotong University and relevant researchers from all over the world published a review article on "Intraspecific, Interspecific and Cross-border Signal Exchange Mediated by Group Induction Signal DSF"
Time of Update: 2022-09-21
Recently, The International Authoritative Review Journal of Microbiology, Trends in Microbiology, published a review article by Professor He Yawen's team at the School of Life Science and Technology o
