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Zhong Qing/Wang Weiwei, School of Basic Medical Sciences, et al. reported a new spray-type contrast agent that rapidly identifies tumor boundaries
Time of Update: 2023-02-03
During surgery, S-4-NP can be directly sprayed with the isolated tumor tissue section, and the tumor tissue can be clearly identified within 3 minutes through near-infrared imaging, thereby helping clinical surgeons quickly distinguish the boundary between tumor tissue and normal tissue, and judge the surgical margin (see Figure 3 for the complete imaging video).
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Why does aging make a person's immune organs filled with fat?
Time of Update: 2023-02-03
A new study by researchers at Uppsala University presents new findings explaining why human lymph nodes lose function with age, and the impact on the effectiveness of our immune system.
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New bacterial therapies for lung cancer are released
Time of Update: 2023-02-03
To test the hypothesis, the researchers blocked these pathways with current anti-cancer drugs and showed that combining the drugs with bacterial toxins was more effective at eliminating lung cancer cells.
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Technology! Chinese scholars bring new expansion microscopy techniques
Time of Update: 2023-02-03
"We overcame some of the long-term challenges of expansion microscopy," says Yongxin Zhao, "and one of Magnify's main selling points is the general strategy of preserving tissue biomolecules, including proteins, nuclear fragments, and carbohydrates, within the expanded sample.
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Wang Zhao's team at Tsinghua University revealed that a high-fat diet rescued the premature aging-related phenotype of SIRT6 knockout mice by improving the intestinal flora
Time of Update: 2023-02-03
Recently, Professor Wang Zhao's research group of Tsinghua University School of Pharmacy published a research paper in the journal Aging Cell entitled: Decreased Enterobacteriaceae translocation due
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iScience: Genome sequencing of endangered sharks
Time of Update: 2023-02-03
Image: Scientists have sequenced the genomes of hammerhead sharks and shortfin mako sharks at the chromosomal level, showing that their populations declined more than 250,000 years ago.
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The study revealed the important role of circadian clock genes in the flight and reproductive behavior of Oriental armyworms
Time of Update: 2023-02-03
Recently, the innovation team of food crop pest monitoring and control of the Institute of Plant Protection of the Chinese Academy of Agricultural Sciences published a paper entitled "The clock gene, period, influences migratory flight and reproduction of the oriental armyworm, Mythimna separata (Walker)" in Insect Science.
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Mechanism by which PASP promotes plant enrichment of heavy metal Cd
Time of Update: 2023-02-03
Article link Fig. 1 Effects of PASP treatment on growth and Cd enrichment of Ghost Needle Grass Fig. 2 Changes in abundance of plant rhizosphere bacterial taxa (genus level) under PASP treatment (red font indicates potential plant growth-promoting bacteria) .
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Nature Biotechnology: Prevents rejection of transplanted cells by tricking antibodies
Time of Update: 2023-02-03
A new approach could overcome the persistent barriers of cell transplantation and immunotherapyResearchers at the University of California, San Francisco, have developed a novel, potentially life-saving way to prevent antibodies from triggering immune rejection in engineered therapy cells and transplanted cells.
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"Nature": Fudan Yuan Peng and others discovered a new mechanism of cognitive decline in Alzheimer's disease patients!
Time of Update: 2023-02-03
The researchers analyzed human brain autopsy samples and found that in the brains of patients with moderate to severe AD, the average number of PAAS near each amyloid plaque was higher and larger, suggesting that the number and size of PAAS may be important factors affecting neural circuit connections and cognitive function in AD patients.
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Immunity: The complexity of TRM cell biology in the gut
Time of Update: 2023-02-03
The researchers observed that TRM cells of each tissue type exhibited different cytokine and granzyme expression patterns, as well as substantial transcriptional, epigenetic, and functional heterogeneity.
The researchers observed that TRM cells of each tissue type exhibited different cytokine and granzyme expression patterns, as well as substantial transcriptional, epigenetic, and functional heterogeneity.
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New progress has been made in analyzing the spatial and temporal differences of estuarine fish communities based on environmental DNA technology
Time of Update: 2023-02-03
Recently, the investigation and assessment team of the South China Sea Fishery Resources Investigation and Assessment Team of the South China Sea Fisheries Research Institute of the Chinese Academy o
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The research of Professor Qian Feng's team of Shanghai Jiaotong University revealed a new mechanism of pneumonia caused by methicillus-resistant Staphylococcus aureus
Time of Update: 2023-02-03
On January 2, 2023, Professor Qian Feng's research group of the School of Pharmacy of Shanghai Jiao Tong University published a report entitled Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to the top international academic journal Nature Microbiology (IF=30.
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Cancer Res: Unravel the mystery of cancer's origins
Time of Update: 2023-02-03
essayGenetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms Is knowing where your ancestors came from the key to better cancer treatment?
essayGenetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms Is knowing where your ancestors came from the key to better cancer treatment?
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Nature Subissue: The secret language of decoding photosynthesis
Time of Update: 2023-02-03
Previously, Chen's team demonstrated that certain proteins in the nucleus of plants are activated by light, initiating photosynthesis.
Previously, Chen's team demonstrated that certain proteins in the nucleus of plants are activated by light, initiating photosynthesis.
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Alzheimer's disease: a gene associated with immune cells in the brain
Time of Update: 2023-02-03
Researchers at Indiana University School of Medicine are studying how to reduce a genetic variant found in brain immune cells that reduces the risk of late-onset Alzheimer's disease.
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Current Biology: Why children learn more efficiently than adults
Time of Update: 2023-02-03
Takeo Watanabe of Brown University said: "Our findings suggest that primary school-age children can learn more than adults in a given amount of time, which makes them learn more efficiently.
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The main pathogen taxa of fungal meningitis are endemic to the regulatory basis and evolutionary pathways of the main pathogen taxa
Time of Update: 2023-02-03
On December 24, 2022, the research team of Wang Linqi, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, published an article entitled "Regulatory basis for reproductive flexibility in a meningitis-causing fungal pathogen" in Nature Communications.
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Brain metastases in melanoma patients, deciphering important molecular mechanisms
Time of Update: 2023-02-03
Different cell states determine the progression of the diseaseThe study's last author, Torben Redmer from the Institute of Medical Biochemistry and Pathology in Vetmeduni, summed up the main findings: "Our study provides evidence that MBMs can be divided into at least two subgroups.
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AD: Middle-aged fat, thin in old age, dementia risk soared 288%!
Time of Update: 2023-02-03
From the results of the Cox regression model (Figure 2), it is not difficult to find that there is no significant statistical association between people with early BMI decline and late BMI decline and the occurrence of dementia.
