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Changes in the intrinsic behavior of neurons
Time of Update: 2023-02-03
Researchers from Harvard's John Paulson School of Engineering and Applied Science (SEAS) and MIT have developed a new method to target diseased neurons in the brain and use light to alter their long-term behavior, paving the way for potential new treatments for neurological disorders such as epilepsy and autism.
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Nature Subissue: The secret language of decoding photosynthesis
Time of Update: 2023-02-03
Previously, Chen's team demonstrated that certain proteins in the nucleus of plants are activated by light, initiating photosynthesis.
Previously, Chen's team demonstrated that certain proteins in the nucleus of plants are activated by light, initiating photosynthesis.
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Alzheimer's disease: a gene associated with immune cells in the brain
Time of Update: 2023-02-03
Researchers at Indiana University School of Medicine are studying how to reduce a genetic variant found in brain immune cells that reduces the risk of late-onset Alzheimer's disease.
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An enzyme that fights off viruses may also accelerate cancer evolution
Time of Update: 2023-02-03
In the new study, Dr. Faltas and his team, including first author Weisi Liu, PhD, postdoctoral research assistant, addressed the specific role of APOBEC3G in bladder cancer through direct causal experiments.
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Mechanism by which PASP promotes plant enrichment of heavy metal Cd
Time of Update: 2023-02-03
Article link Fig. 1 Effects of PASP treatment on growth and Cd enrichment of Ghost Needle Grass Fig. 2 Changes in abundance of plant rhizosphere bacterial taxa (genus level) under PASP treatment (red font indicates potential plant growth-promoting bacteria) .
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The research of Professor Qian Feng's team of Shanghai Jiaotong University revealed a new mechanism of pneumonia caused by methicillus-resistant Staphylococcus aureus
Time of Update: 2023-02-03
On January 2, 2023, Professor Qian Feng's research group of the School of Pharmacy of Shanghai Jiao Tong University published a report entitled Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to the top international academic journal Nature Microbiology (IF=30.
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Technology! Chinese scholars bring new expansion microscopy techniques
Time of Update: 2023-02-03
"We overcame some of the long-term challenges of expansion microscopy," says Yongxin Zhao, "and one of Magnify's main selling points is the general strategy of preserving tissue biomolecules, including proteins, nuclear fragments, and carbohydrates, within the expanded sample.
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New bacterial therapies for lung cancer
Time of Update: 2023-02-03
Researchers at Columbia University's School of Engineering report that they have developed a preclinical evaluation pipeline for the characterization of bacterial therapies in lung cancer models.
Researchers at Columbia University's School of Engineering report that they have developed a preclinical evaluation pipeline for the characterization of bacterial therapies in lung cancer models.
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Science: Chinese scientists led the way in revealing that the ketogenic diet is expected to become a potentially life-saving therapy for cancer patients to combat low platelets
Time of Update: 2023-02-03
In a new preliminary study, researchers from research institutions such as Fudan University in China and Longyan First Hospital affiliated to Fujian Medical University suggest that a high-fat diet ma
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New peptides with potential beyond existing anti-cancer drugs
Time of Update: 2023-02-03
The cyclic peptides recently discovered by the researchers have the ability to specifically bind to ubiquitin protein chains, which are often used as "death tags" for damaged proteins.
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Heavy! NEJM: The efficacy of domestic new crown oral drugs is not inferior to Paxlovid and the safety is better
Time of Update: 2023-02-03
The results showed that for adult patients with mild to moderate Covid-19 with high-risk factors, domestic VV116 was not inferior to Paxlovid in terms of duration of clinical recovery (4 versus 5 days; Risk ratio, 1.
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Trends in Plant Science: A high-throughput screening strategy for non-toxic genes of multi-pile rust fungus and resistance genes of maize to southern rust was proposed
Time of Update: 2023-02-03
High-throughput screening strategies for non-toxic genes and maize disease resistance genes in multi-pile rust bacteria The southern rust of maize caused by the infestation of Puccinia polysora underw is widely epidemic in the world, which seriously threatens the safe production of maize in China and the world, and sustainable control of maize southern rust urgently needs reasonable and effective cultivation and planting of resistant varieties.
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Japanese scientists expand stockpile of drugs to fight COVID-19
Time of Update: 2023-02-03
While testing a group of compounds known to have inhibitory activity against the 2002 SARS-CoV virus, the research team identified a compound called 5h, which showed activity to inhibit SARS-CoV-2 Mpro, but was inefficient and unstable.
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Cancer Res: Unravel the mystery of cancer's origins
Time of Update: 2023-02-03
essayGenetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms Is knowing where your ancestors came from the key to better cancer treatment?
essayGenetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms Is knowing where your ancestors came from the key to better cancer treatment?
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Zoological Research Institute collaborates to reveal that the human genome archaea resurrection drives aging
Time of Update: 2023-02-03
The study systematically defined and revealed aging-i nduced r esurrection of endogenousretrov irus, AIR-ERV) can be used as the driving force and measurement marker of aging in cells, organs and even the body, providing a new theoretical basis for the programmatic, cascading amplification and interventionability of aging, and providing important clues and ideas for the scientific assessment and early warning of human aging, and the prevention and treatment of aging and aging-related diseases.
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Xanthan gum liquid thickener helps lower blood sugar levels
Time of Update: 2023-02-03
Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome Long-term consumption of xanthan gum liquid thickener.
Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome
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Use the sword of biological network big data to solve the mystery of corn genetics
Time of Update: 2023-02-03
Inheritance and innovation kicked off the era of maize multi-dimensional network map On December 30, 2022, the journal Nature and Genetics published the collaborative research paper "A multi-omics in
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NEJM: The world's first successful treatment of a rare genetic disease in an unborn baby in utero
Time of Update: 2023-02-03
Doctors and researchers at the University of California, San Francisco, Duke University and the University of Ottawa have successfully used enzyme replacement therapy (ERT) for the first time to treat a fetus with Pompe disease still in the womb, and the little girl is now one and a half years old, has reached developmental milestones, has a normal heart and muscle function, can walk, and has normal biomarkers of muscle damage and glycogen accumulation.
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The reason why Nature Neuroscience feels like "the brain is about to explode."
Time of Update: 2023-02-03
”Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience Over time, new experiences are absorbed into neural representations, here represented by hyperboloid hourglasses.
”Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience Over time, new experiences are absorbed into neural representations, here represented by hyperboloid hourglasses.
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The He Hang-Deng Xingwang team successfully constructed the T2T genome maps of two kiwifruit species
Time of Update: 2023-02-03
Under the condition that China's arable land area is limited, greatly improving crop yield and quality is an inevitable way to meet agricultural security and develop agricultural economy. With the ap
