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Counterintuitive?
Time of Update: 2021-11-12
Co-lead author Professor Stephen Moss (University College London Institute of Ophthalmology) said: "Although it is counterintuitive that finding a way to normalize cancer tumor blood vessels has become a clinical goal, identifying an effective treatment tool has been proven It is difficult to achieve .
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Cambridge University "antivirus" air filtration system-innovative nanomaterials can eliminate viruses, including coronaviruses
Time of Update: 2021-11-12
The ultra-thin carbon nanotube conductive film, a new type of conductive filter film, is heated to a temperature above 100°C through resistance, so that viruses (including β-coronavirus) lose their activity within a few seconds, thereby achieving virus filtration and disinfection through hot flash .
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One drug has the potential to curb multiple cancers
Time of Update: 2021-11-12
Westover’s laboratory has collaborated with the Dana-Farber Cancer Institute to develop a drug that binds to specific RAS mutants, the glycine at position 12 in the RAS mutant The amino acid is converted to cysteine, the so-called KRAS G12C .
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Cell Rep: Strategies for Remyelination
Time of Update: 2021-11-12
"To study the relevance of this observation, the researchers genetically inactivated the synthesis of cholesterol in mouse neurons and myelin-forming cells (oligodendrocytes) .
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eLife: Researchers have successfully identified a protein in the coronavirus that can destroy blood vessels
Time of Update: 2021-11-12
Now, for the first time, a team of experts led by Tel Aviv University has been able to identify five of the 29 proteins that make up this blood vessel-damaging virus .
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Professor Li Yulong was invited to be interviewed by "Neuron" magazine and talked about the development of optical imaging tools and whole brain research
Time of Update: 2021-11-12
In the "Neuron" special issue published on November 3, 2021, Professor Li Yulong personally shared a number of important issues related to the development of optical imaging tools and the study of the whole brain in the form of question-and-answer interviews .
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Treat brain tumors!
Time of Update: 2021-11-12
CompilenewbornRecently, GlaxoSmithKline (GSK) and Ivy Brain Tumor Center announced the initiation of a phase 0 clinical trial (NCT05076513) to evaluate Zejula (niraparib) for the treatment of newly diagnosed glioblastoma Efficacy and safety in patients with cell tumor (GBM) and recurrent glioma (Grade II-IV) .
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Science good news: RNA drugs for patients with rare genetic diseases are coming out soon
Time of Update: 2021-11-11
This drug : The story of milasen (named after the girl Mila) has inspired people to use short-stranded RNA (called antisense oligonucleotides (ASOs)) for more personalized treatments that can overcome genetic defects .
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"Science Advances" Live Skin DNA Transfection Platform: Similar to "Cupping" of Traditional Chinese Medicine
Time of Update: 2021-11-11
This method provides an easy-to-use, cost-effective and highly scalable platform for the laboratory transfection requirements and clinical applications of nucleic acid therapy and vaccines .
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PNAS: By blocking the Bach1 protein, the degeneration of brain cells in Parkinson's disease patients is slowed down
Time of Update: 2021-11-11
To confirm this, the researchers consumed Bach1 in a mouse model of PD and showed that dopamine-producing neurons are protected by some destructive stress pathways .
Another key question is the benefits of modulating this pathway in chronic models of Parkinson's disease, other cell types in the brain, and potentially other dementias .
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Microbial electrosynthesis!
Time of Update: 2021-11-11
A research team from the University of Washington modified a bacterium called Rhodopseudomonas palustris so that it can use only three renewable, naturally abundant raw materials: carbon dioxide, produced by solar panels Electricity and light are used to produce biofuels .
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The latest paper from Southern Medical University discovers new neural circuits and molecular mechanisms for anxiety and fear emotions
Time of Update: 2021-11-11
On October 26, 2021, Tianming Gao's team from our school published a research paper entitled "PV Network Plasticity Mediated by Neuregulin1-ErbB4 Signalling Controls Fear Extinction" in Molecular Psychiatry (impact factor 15.
This study revealed the local molecular loop mechanism of mPFC-mediated "top-down" regulation of fear memory fading .
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Xue Yongbiao's research team collaborated to reveal the highly dynamic evolutionary mechanism of the origin, loss and regain of self-incompatibility in angiosperms
Time of Update: 2021-11-11
Among them, the type 1 S site often contains one S- nuclease and multiple SLFs , which respectively encode female and male self-incompatibility determinants .
Figure: The origin, loss and regain mechanism of self-incompatibility in flowering plants
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How to correctly select active genes
Time of Update: 2021-11-11
The collaboration of scientists at the University of Barna-Champaign has now made a new discovery in the formation of a transcription factory: it is similar to the condensation of liquids .
The combination of observation and simulation makes the condensation process reproducible and explains how living cells can quickly and reliably build transcription factories .
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Researcher Zhang Lin from the School of Physics and collaborators have made important progress in the research on the PM2.5 health effects of global agricultural ammonia nitrogen
Time of Update: 2021-11-11
9" >Researcher Zhang Lin from the Department of Atmospheric and Oceanic Sciences, School of Physics, Peking University, researcher Gu Baojing from Zhejiang University, and Professor Mark Sutton from the British Eco-Hydrology Center have made important progress in the study of the atmospheric environment and health effects of global nitrogen emissions .
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Use stem cells to quickly mass produce any cell type in the human body
Time of Update: 2021-11-11
bio are glutamatergic neurons and skeletal muscle cells generated by reprogramming iPSCs using opti-ox technology .
The company pointed out that this technology can precisely control the expression of specific transcription factor combinations, thereby determining the cell types differentiated by human iPSCs.
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New breakthrough in the research of hydrogen peroxide nanoenzymes
Time of Update: 2021-11-11
Recently, the team of Academician Yan Xiyun, Gao Lizeng and Fan Kelong of the Institute of Biophysics of the Chinese Academy of Sciences/Nanoenzyme Engineering Laboratory of the Chinese Academy of Sciences discovered that ferrihydrite (Fe 5 HO 8 ·4H 2 O ) Is a relatively specific hydrogen peroxide-like nanoenzyme, which can be effectively catabolized by cells and has good biocompatibility .
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Nature: Sponge cells suggest the origin of the nervous system
Time of Update: 2021-11-11
Kathy Dunn, an evolutionary biologist at Yale University in New Haven, Connecticut, who studies marine invertebrates, said these findings help understand how animals’ nervous systems evolve .
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If cancer cells are injected into healthy people, will they get cancer?
Time of Update: 2021-11-11
So, if a researcher who is exposed to HeLa cells every day accidentally injects HeLa cells into the body, will there be a risk of cancer spreading?In view of this, the medical scientist Chester Southam decided to conduct human experiments .
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Ibrutinib can improve the survival of young patients with diffuse large b-cell lymphoma
Time of Update: 2021-11-11
Figure: The addition of ibrutinib to R-CHOP chemotherapy improves the overall survival of trial participants 60 years of age and younger with MCD or N1 subtype non-gcb diffuse large B-cell lymphomaSource: National Institutes of Health (NCI)New evidence shows that adding targeted therapy ibrutinib (Imbruvica) to standard chemotherapy regimens can improve the survival time of some young patients with diffuse large b-cell lymphoma (DLBCL) .