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Osaikang has accumulated a lot to release the first class 1 new drug benchmarking 4 billion varieties!
Time of Update: 2022-05-01
with PD-1/L1 antibody showed a significant synergistic anti-tumor effect, and also effectively inhibited the metastasis of cancer cells . In the field of anti-tumor drugs, Osaikang's first class 1
Osaikang has accumulated a lot, and the first class 1 new drug is benchmarked against 4 billion varieties!
Time of Update: 2022-05-01
with PD-1/L1 antibody showed a significant synergistic anti-tumor effect, and also effectively inhibited the metastasis of cancer cells . In the field of anti-tumor drugs, Osaikang's first class 1
The latest research finds: more than 1/4 of the elderly in rural areas are at high risk of dementia?
Time of Update: 2022-04-28
At the same time, this study suggests that advanced age, low education level and non-mental work may increase the risk of MCI, while the history of hypertension and stroke may increase the possibility of naMCI .
Asia's largest offshore conjoined platform transports nearly 4 billion cubic meters of natural gas to the Bohai Rim region
Time of Update: 2022-04-27
On April 1, the reporter learned from the Liaodong Operation Company of CNOOC Tianjin Branch that the Jinzhou 25-1 South oil and gas field, which has the largest offshore "Four-star Lianzhu
ExxonMobil's Brazil exploration may reach 1 billion barrels of oil and gas resources
Time of Update: 2022-04-26
S. oil producer Exxon Mobil Corp's partner Murphy Petroleum said on Tuesday it was exploring a new area offshore Brazil that could hold as much as 1 billion barrels.
Clinical Study of Its CD40 mAb YH003 Combined with CTLA-4 mAb YH001 and PD-1 mAb
Time of Update: 2022-04-25
Yimaike's recent hot reports ★Two "blockbusters", marketed ADC drugs are leading the way ★Biosetu/Youhe international clinical research has entered a new journey: 4-1BB monoclonal antibody completed the first
Age & Ageing: In 1 in 4 hospitalizations, recurrent delirium can increase dementia risk by 7.8 times!
Time of Update: 2022-04-24
Taken together, delirium increases the risk of future cognitive decline and dementia independent of disease severity and baseline cognitive performance, with more episodes associated with worse cognitive performance .
Lancet Sub-Journal: In 1 in 4 hospitalizations, what is the impact of delirium on long-term cognitive impairment and mortality?
Time of Update: 2022-04-24
The clinical importance of delirium has been demonstrated as acute changes in arousal, inattention, and overall cognitive impairment, affecting 1 in 4 elderly (≥70 years of age) hospitalized patients .
4 pharmaceutical companies reported good annual results, and 1 traditional Chinese medicine company's net profit increased by over 900%
Time of Update: 2022-04-20
/> Among them, CHC health consumer goods business achieved revenue of 9. 276 billion yuan, a year-on-year increase of 17. 72%; prescription drug business achieved revenue of 5. 350 billion yuan, a year-on-year
Cardiovasc Diabetol: Effects of GLP-1 agonists vs SGLT-2 inhibitors vs DPP-4 inhibitors on cardiorenal outcomes in patients with T2DM
Time of Update: 2022-04-20
This study was a network meta-analysis to compare the effects of GLP-1 RA, SGLT-2 inhibitors, and dipeptidyl peptidase 4 (DPP-4) inhibitors on cardiorenal outcomes in patients with type 2 diabetes .
JAMA Netw Open: Association of glucagon-like peptide-1 receptor agonist versus dipeptidyl peptidase
Time of Update: 2022-04-20
Analysis of primary and secondary outcomesConclusions: In patients with type 2 diabetes, advanced CKD, and ESKD, treatment with GLP-1 receptor agonists was associated with lower all-cause mortality than patients with DPP-4 inhibitors .
Association of GLP-1 receptor agonist and DPP-4 inhibitor use with mortality in patients with type 2 diabetes and advanced chronic kidney disease
Time of Update: 2022-04-20
In conclusion, the results of this study show that GLP-1 receptor agonist treatment is associated with reduced all-cause mortality in patients with type 2 diabetes, advanced CKD and ESKD compared with DPP-4 inhibitors .
Arthritis: Interleukin 1 receptor-related kinase 4 inhibitor PF-06650833 blocks a preclinical model of rheumatism
Time of Update: 2022-04-17
In the current study, we demonstrate that PF-06650833, a small-molecule inhibitor of IRAK4, reduces responses to disease-related stimuli in human cells as well as in animal models of rheumatoid arthritis and systemic lupus erythematosus .
(1)-Eugenol-4-O-β-D-Furanosyl-(1→-2)-β-D-glucopyranoside
Time of Update: 2022-04-07
Thin layer plate silica gel GDeveloping solvent of chloroform - methanol - water (13: 5: 2) was lowerCheck the 5% phosphomolybdic acid ethanol solution, heat it at 90℃ until the spots are clearly colored, and then check under sunlight2.
Determination of Alkyl Mercury in Solid Waste Leachate Purge and Trap/Gas Chromatography-Cold Atomic Fluorescence Method (1)
Time of Update: 2022-03-12
Five, pre-treatment(1) Preparation of leaching solution"Semi-Volatile Organic Compound Analysis Technology-Preparation of Sulfuric Acid and Nitric Acid from Leachate"(2) Steaming letterAccurately measure 45mL pure water (or sample, need to add 0.
Solid waste leachate-determination of organochlorine pesticides-gas chromatography (1)
Time of Update: 2022-03-12
Acid and Nitric Acid from Leachate">(2) Extraction>Take 100 mL of the extract in a separatory funnel, add 5 g of sodium chloride, shake, shake, and then add 20 mL of dichloromethane