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Express 75% of patients maintained complete remission after one year, with positive Phase 2

 Time of Update: 2022-06-17

▎WuXi AppTec Content Team Editor Today, CG Oncology announced that the company's oncolytic virus therapy CG0070, in combination with Merck's anti-PD-1 antibody Keytruda, has been approved in a Phase 2 clinical trial for the treatment of non-muscle invasive bladder cancer.
analyzed the mechanism of infection enhancement and immune escape of Omicron BA.1 and BA.2, and explored the potential evolutionary path of Omicron

 Time of Update: 2022-06-14

-peer-reviewed article titled "Structural and biochemical mechanism for increased infectivity and immunity on the preprint platform bioRxiv. evasion of Omicron BA. 1 and BA. 2 variants and their mouse origins” research paper
More protection against variants such as Omicron, Moderna releases clinical data of the first bivalent mRNA new crown vaccine (Phase 2/3)

 Time of Update: 2022-06-12

211 compared to mRNA-1273, the currently used mRNA new crown vaccine against the original virus strain SARS-CoV-2 .
Photovoltaic will become the most economical power source in the next 2-3 years

 Time of Update: 2022-06-10

In the past two years, in areas with good sunlight resources and relatively low non-technical costs, photovoltaic feed-in tariffs have continued to break records.
The "1, 3, 5, 7, 9" principles of the Diabetes Movement and the "Grassroots Diabetes DSMES Consensus" have been released!

 Time of Update: 2022-06-02

/> Follow the doctor's orders to take medication and comprehensive treatment to prevent complications . When adverse drug reactions occur
Express first-line treatment of esophageal cancer, BeiGene/Novartis PD-1 antibody combination

 Time of Update: 2022-05-31

treatment of advanced stage or met the primary endpoint in a phase 3 clinical trial in patients with metastatic esophageal squamous cell carcinoma (ESCC) . An interim analysis
2022CSCO Prof. Yin Yongmei: 3 major update points of HER-2 positive breast cancer diagnosis and treatment guidelines

 Time of Update: 2022-05-21

to start the authoritative update, release, interpretation and discussion of the CSCO series of guidelines that closely follow the cutting-edge tumor research and the status of clinical diagnosis
The world's first bivalent new crown vaccine Phase 2/3 clinical results announced

 Time of Update: 2022-05-17

It is worth mentioning that Livzon Group, a Chinese pharmaceutical company, is also developing the Beta/Delta bivalent new crown vaccine . https:// Johnny and Weibo2.
NEJM: The infection rate has dropped by 2 times, and the severe disease rate has dropped by 3 times!

 Time of Update: 2022-05-17

In an adjusted ratio-difference analysis, the four-dose group reduced confirmed infections by 170 cases per 100,000 person-days (95% CI, 162-176) compared with the three-dose group at week 4, which was 137 fewer than the internal control group.
Cardiovasc Diabetol: Effects of DPP-4 Inhibitors, GLP-1 Receptor Agonists, and SGLT-2 Inhibitors on Cardiorenal Outcomes

 Time of Update: 2022-05-12

DPP-4i: dipeptidyl peptidase-4 inhibitor; PL: placebo; GLP-1RA: glucagon-like peptide-1 receptor agonist; SGLT-2i: sodium-glucose co-transporter-2 inhibitorFigure 2 Forest plot of the meta-analysis network for cardiovascular death, total death, heart failure hospitalization, and renal outcomes .
The price of Vietnamese chili has increased by 2-3 times

 Time of Update: 2022-05-10

In the past two days, the price of chili peppers in Vietnam's provinces such as Binh Dinh, Gia Lai, and Nghe An has suddenly tripled .
Sunshine Pharmaceuticals will attack 1 new drug and 3 hot varieties are just around the corner

 Time of Update: 2022-05-02

　　On February 23, Guangdong Sunshine Pharmaceutical submitted a new drug clinical application for class 1 new
22 ophthalmology category 1 new drugs are coming to Hengrui, 3 new drugs are expected to be launched

 Time of Update: 2022-05-01

new drug RA1115-B1 eye drops has been submitted for clinical application. Domestic new ophthalmic drugs (22 category 1 new drugs) are in the stage of clinical application and above, and 3 new drugs of Hengrui are expected to be launched
Denali macromolecule delivery technology that breaks through the blood-brain barrier is expected to advance to phase 2/3 clinical trials

 Time of Update: 2022-05-01

Long-term data from 20 patients showed that after up to 1 year of administration, the drug could continue to reduce the level of disease-related biomarkers in the patient's brain, and initially improve clinical symptoms, with a good safety profile .
A new strain of Omicron appeared, XE, which is a combination of BA.1 and BA.2, spreading 10% faster than BA.2!

 Time of Update: 2022-04-28

The UK Health and Safety Agency (UKHSA) has confirmed that a recombinant variant of the Omicron sub-strain has been found in the UK, currently named XE!
Positive Phase 2 Clinical Results of Muscular Dystrophy Therapy Start Phase 3 Clinical Trial This Year

 Time of Update: 2022-04-28

and usefulness of selected clinical efficacy and pharmacodynamic assessment assays, in 3 cohorts of LGMD2i patients . Data observed after 90 and 180 days of treatment indicated:>
2 Figure 3 Table to teach you the diagnostic chart summary of autoimmune encephalitis

 Time of Update: 2022-04-28

vascular enhancement, responsive to steroids; CPM, central pontine myelinolysis; CSF, cerebrospinal fluid; DaT scan, dopamine transporter scan; ENA, possible Extracted nuclear antigen; GFAP, glial fibrillary acidic protein; GPA, glioma with polyangiitis
Medrxiv: The strongest new crown Omicron mutant strain XE, how did BA.1 and BA.2 recombine, and what mutations were there?

 Time of Update: 2022-04-27

The vacuole-making protein NSP4 NSP4 binds to other proteins to help form the fluid-filled bubble structure within infected cells, where some of the new viruses are built .
The pivotal Phase 3 clinical results of Express IL-2 receptor-targeted therapy are positive

 Time of Update: 2022-04-25

▎WuXi AppTec content team editors Today, Citius Pharmaceuticals announced that its investigational therapy I/ONTAK (E7777) has achieved positive top line in a pivotal Phase 3 clinical trial in patients with persistent or relapsed cutaneous T-cell lymphoma (CTCL).
JAMA: 2-dose versus 3-dose hepatitis B vaccine causes no difference in acute myocardial infarction

 Time of Update: 2022-04-24

myocardial infarctionTo compare acute MI rates between recipients of HepB-CpG vaccine and HepB-alum vaccine, scholars from the United States conducted a prospective cohort non-inferiority study, and the results were published in the journal JAMA .

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