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3 methyl 2 nitrophenol

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2022CSCO Prof. Yin Yongmei: 3 major update points of HER-2 positive breast cancer diagnosis and treatment guidelines

 Time of Update: 2022-05-21

to start the authoritative update, release, interpretation and discussion of the CSCO series of guidelines that closely follow the cutting-edge tumor research and the status of clinical diagnosis
NEJM: The infection rate has dropped by 2 times, and the severe disease rate has dropped by 3 times!

 Time of Update: 2022-05-17

In an adjusted ratio-difference analysis, the four-dose group reduced confirmed infections by 170 cases per 100,000 person-days (95% CI, 162-176) compared with the three-dose group at week 4, which was 137 fewer than the internal control group.
The world's first bivalent new crown vaccine Phase 2/3 clinical results announced

 Time of Update: 2022-05-17

It is worth mentioning that Livzon Group, a Chinese pharmaceutical company, is also developing the Beta/Delta bivalent new crown vaccine . https:// Johnny and Weibo2.
The price of Vietnamese chili has increased by 2-3 times

 Time of Update: 2022-05-10

In the past two days, the price of chili peppers in Vietnam's provinces such as Binh Dinh, Gia Lai, and Nghe An has suddenly tripled .
Denali macromolecule delivery technology that breaks through the blood-brain barrier is expected to advance to phase 2/3 clinical trials

 Time of Update: 2022-05-01

Long-term data from 20 patients showed that after up to 1 year of administration, the drug could continue to reduce the level of disease-related biomarkers in the patient's brain, and initially improve clinical symptoms, with a good safety profile .
Positive Phase 2 Clinical Results of Muscular Dystrophy Therapy Start Phase 3 Clinical Trial This Year

 Time of Update: 2022-04-28

and usefulness of selected clinical efficacy and pharmacodynamic assessment assays, in 3 cohorts of LGMD2i patients . Data observed after 90 and 180 days of treatment indicated:>
2 Figure 3 Table to teach you the diagnostic chart summary of autoimmune encephalitis

 Time of Update: 2022-04-28

vascular enhancement, responsive to steroids; CPM, central pontine myelinolysis; CSF, cerebrospinal fluid; DaT scan, dopamine transporter scan; ENA, possible Extracted nuclear antigen; GFAP, glial fibrillary acidic protein; GPA, glioma with polyangiitis
The pivotal Phase 3 clinical results of Express IL-2 receptor-targeted therapy are positive

 Time of Update: 2022-04-25

▎WuXi AppTec content team editors Today, Citius Pharmaceuticals announced that its investigational therapy I/ONTAK (E7777) has achieved positive top line in a pivotal Phase 3 clinical trial in patients with persistent or relapsed cutaneous T-cell lymphoma (CTCL).
JAMA: 2-dose versus 3-dose hepatitis B vaccine causes no difference in acute myocardial infarction

 Time of Update: 2022-04-24

myocardial infarctionTo compare acute MI rates between recipients of HepB-CpG vaccine and HepB-alum vaccine, scholars from the United States conducted a prospective cohort non-inferiority study, and the results were published in the journal JAMA .
Positive Phase 2 Clinical Results of LAG-3 Therapy for Non-Small Cell Lung Cancer

 Time of Update: 2022-04-22

"References:[1] Immutep's efti in combination with MSD's pembrolizumab shows encouraging antitumor activity in difficult to treat 2nd line metastatic lung cancer patients.
Phase 2/3 clinical trials of Moderna's COVID-19 vaccine for children under 6 years old meet primary endpoint

 Time of Update: 2022-04-22

are accumulated . Overall, Moderna has enrolled approximately 11,700 pediatric participants in the U. S. and Canada, including approximately 4,200 children 2 to under 6 years of age
Cardiovasc Diabetol: Effects of Liraglutide and Lifestyle Modification on Sst2 and Galectin-3

 Time of Update: 2022-04-20

>Figure 3 Effects of intervention on plasma ST2 and Gal-3 levels during OGTT . Levels of Sst2 and Gal-3 in OGTT of life>>Figure 3 Effects of intervention
The pivotal Phase 3 clinical results of IL-2 receptor targeted therapy are positive

 Time of Update: 2022-04-17

Today, Citius Pharmaceuticals announced positive top-line results from a pivotal Phase 3 clinical trial of its investigational therapy I/ONTAK (E7777) in patients with persistent or relapsed cutaneous T-cell lymphoma (CTCL) .
3 pharmaceutical companies have reviewed 7 varieties, and 2 varieties have been subsidized by 1.5 million yuan each!

 Time of Update: 2022-04-15

million yuan . 　　Among them, the sarpogrelate hydrochloride tablets of Jiangsu Wangao Pharmaceutical passed the consistency evaluation .
Cancer: Short-term (2-3 years) adjuvant endocrine therapy is an optional treatment option

 Time of Update: 2022-04-15

Recently, the journal Cancer published the results of a retrospective propensity-matched analysis from Fudan University Cancer Hospital , mainly evaluating the use of short-course (2-3 years) adjuvant in patients with ER-positive low-expression (IHC 1%-10%) breast cancer.
AstraZeneca abandoned the new crown vaccine for beta variants and has entered clinical phase 2/3!

 Time of Update: 2022-03-08

Given the small genetic differences between the beta variant and the original SARS-CoV-2 virus, AstraZeneca responded by tweaking its first-generation Vaxzevria vaccine .
Express breaks through the blood-brain barrier, Denali macromolecule delivery technology is expected to advance to Phase 2/3 clinical trials

 Time of Update: 2022-03-08

Long-term data from 20 patients showed that after up to 1 year of administration, the drug could continue to reduce the level of disease-related biomarkers in the patient's brain, and initially improve clinical symptoms, with a good safety profile .
LCAH: Physical and mental health of UK adolescents 3 months after SARS-CoV-2 infection (CLOCK)

 Time of Update: 2022-03-02

was administered to a group of adolescents to collect demographic and physical and mental health data at the time of PCR testing (retrospective) and at the time of questionnaire completion (prospective) . We
Gritstone bio's innovative cancer vaccine enters phase 2/3 clinical trial

 Time of Update: 2022-02-23

References:[1] Gritstone Announces First Patient Enrolled for Phase 2/3 Trial Evaluating Individualized Neoantigen Vaccine GRANITE for First Line (1L) Maintenance Treatment of Metastatic, Microsatellite-Stable Colorectal Cancer (MSS-CRC).
【Literature Interpretation】: A recent meta-analysis: changes in motor function in patients with type 2 and type 3 SMA after treatment with nosinasan

 Time of Update: 2022-02-22

Introduction Spinal muscular atrophy (SMA

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